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Re: Is it me or is Apigenin not so hot in this forum
Unless you do expensive tests, who knows what really works in your own body? My attitude is: It's cheap, it's harmless, why not, when studies show it's beneficial?
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Hair regrowth
I don't know if this was mentioned before: Propecia 1mg (or buy 5gm and use a pill cutter to cut into 4, it's much cheaper). Scientifically proven to work for male pattern balding.
- Andrew_P_K_Yap
- 5 yrs ago
- General Discussion
- Reported - view
Re: Long term damage of non hospitalized positive COVID-19.
Long term ill effects from covid19 comes from "damage to lung tissue" and "damage to the linings of blood vessels". You can do lung capacity tests. As for damage to linings of blood vessels,…
- Andrew_P_K_Yap
- 5 yrs ago
- 1
- Questions & Answers
- Reported - view
Re: Fisetin to Clear Senescent Cells
@BobM You might want to take these 2 supplements: 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/ In contrast, vitamin K2 is associated with the inhibition of arterial calcification and…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689181/ I have not read anything about it being toxic and instead read about how safe it is.…
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Senolytics and Female Fertility
All I can say is, after successful aging reversal, my libido reverted back to when I was at least 10 years younger. Not necessarily a good thing you understand. But that's what I noticed.
- Andrew_P_K_Yap
- 5 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield I was contrasting between Fisetin, which is found in "edible plants" and Rapamycin which is a drug prescribed for organ transplant patients.…
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield Another thing, take it intermittently, don't take it continuously. Just common sense.
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew P K Yap Rapamycin, I saw a David Sinclair interview where he said he wouldn't take it.
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield It should be safe. Just watch out for upset stomach. From what I know these stuff from edible plants, that is as bad as it gets, needing to go to the toilet more than usual.…
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield Fisetin is in fruits. However, it is most commonly found in these superfoods: Strawberries. Mangoes. Cucumber with skin. Apples. Persimmons. Kiwi. Peaches. Grapes.
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
QUESTION: While the ages estimated by epigenetic clocks often correlate very well with chronological age, it is not clear whether the DNA methylation profiles in the clocks directly contribute to…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Is it me or is Apigenin not so hot in this forum

Treatment of cells with apigenin or quercetin inhibits CD38 and promotes an increase in intracellular NAD+ levels. An increased NAD+ level decreases protein acetylation through sirtuin activation. ..…
- Andrew_P_K_Yap
- 5 yrs ago
- 21replies
- 706
- Self-Experimentation
"Insufficient" dosage leads to "no effect" or "small effect"?

My assumption is that scientific researchers need to "show immediate results" and that is why they use such, in some cases, massive dosages. We, on the other hand,…
- Andrew_P_K_Yap
- 5 yrs ago
- 184
- 1
- General Discussion
Re: Introduction to Young Plasma Infusions
@JGC Just guessing but it seems that there is a rejuvenating effect - repair of aged organs - and that is why there is a long lasting effect.
- Andrew_P_K_Yap
- 5 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Sources of dasatinib
@Pablo Reinaldos López There is a lot of good information, just Google and read them, the good ones.
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Sources of dasatinib
@Pablo Reinaldos López If I were you, I won't trust "This person's opinion" and "That person's opinion" no matter what they say their credentials are. It's better that you do your own research.
- Andrew_P_K_Yap
- 5 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Sources of dasatinib
@Pablo Reinaldos López I clicked on the link you provided, http://www.anti-agingfirewalls.com/2018/09/02/aging-cell-and-tissue-repair-renewal-andregeneration-inflammation-and-the-sasp it says Page…
- Andrew_P_K_Yap
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
@Staffan Olsson Thanks to you I am now acquainted with: TMG Trimethylglycine and Alpha-Ketoglutarate
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: 32 years old. Is self-experimentation right for me?
Wouldn't it be nice, if you can maintain your looks now, into your fifties, sixties and beyond... and at your present level of health and fitness. I am 60 and sure,…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Senolytic Self-experiments and COVID-19
https://www.fightaging.org/archives/2016/11/senescent-cells-may-enhance-viral-replication-making-infections-more-dangerous/ November 4th, 2016 Senescent Cells May Enhance Viral Replication,…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
https://www.activemotif.com/blog-reversing-epigenetic-age Epigenetic Aging Reversal Clinical Trial Design The treatment cocktail used in the clinical trial included recombinant human growth hormone…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392256/ At the FDA, scientists are investigating many drugs that function through epigenetic mechanisms (although as spokes-woman Christine Parker notes,…
- Andrew_P_K_Yap
- 5 yrs ago
- Self-Experimentation
- Reported - view
EPIGENETIC MUTATIONS, REVERSAL TO NORMAL

Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks
- Andrew_P_K_Yap
- 5 yrs ago
- 11replies
- 264
- Self-Experimentation
Re: Did anyone experience acute inflammation after senolytics?
From my experience, it can take many months to years to see results. In the meantime, there will be side effects.
- Andrew_P_K_Yap
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view

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