The Conboy Plasma-Dilution Treatment is Available Now

    Recently, watching a video interview of Irina Conboy, I became aware that Conboy plasma-dilution for humans is available in San Francisco and Miami from the medical practice of Dobri Kiprov, MD, who works with and has published with Profs. Irina and Michael Conboy of UC Berkeley.  Here are links to videos and writeups about Dr. Kiprov's work on plasma dilution:
https://youtu.be/5gGFJtKIUN0
https://neo.life/2021/06/perspective-therapeutic-plasma-exchange-the-future-of-aging/
https://www.TPEplus.com

    I contacted Dr. Kiprov and had a Zoom call with him this morning.  Here's what I learned:

  • Kiprov's plasma-dilution protocol is slightly different from that described in the Conboy papers.  He adds some proprietary ingredients to the saline + albumin to suppress negative immune reactions.  I suspect that said reactions are caused by a stabilizer component that is in the albumin.
  • Treatment for one person involving two sessions of plasma dilution spaced 2 days apart costs $6,000.  There is a discount if a couple both have treatments at the same time.
  • Several patients have had Horvath-type DNAm bio-age tests before and after treatment.  The apparent epigenetic reset from the treatment is about 3-4 years.  Kiprov does not think the epigenetic reprogramming is "permanent".
  • The effects of the plasma dilution sessions are cumulative, and Kiprov recommends that they be done monthly for about 6 months, with semi-yearly or yearly treatments after that.
  • The observations of recipients are that there are immediate benefits from a plasma dilution session, but they are observed to diminish in a few weeks.  This motivates the repeated sessions.
  • There are plans to set up more centers to perform plasma-dilution treatments at other population centers around the USA.  No decisions yet about where.

    I am considering arranging one set of plasma-dilution sessions for my wife and me next December (for ~$10k), but I don't think we can afford a full 6-month series of them (~$60k).  Also, I am disappointed to learn that the apparent epigenetic reset of the Conboy treatment is only a few years.  According to the paper published with Steve Horvath, Harold Katcher's E-5 treatment on rats produced an epigenetic reset by about a factor of 2.

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  • Thanks so much for the info !

    and damn, this was such a disapointment. now i also know why irina never responded to my email. I asked about EU clinics in the future, where they plan to be set up.

    And then i asked about the pricing range and said that 600 euro would be a ok price for something like this, but that corperations are greedy so i bet its 1000 euro per session ... but what, 6000 dollars !?? and its suppose to be given multiple times per week and then every month and then every 6 months ... seriously

    No thanks, i settle with blood donations and a 80% reduced mortality, increase in stem cells, bone growth, neurogenesis, removal off senesent cells. all for free .......... is this why irina talk down on blood donation "it wont work", cause her treatment will be a robbery money wise so it will sound like her treatment is the only thing that works. hmm 

    Also its strange that they dident recive better effect from new  fresh albumin ? mice study shows 20% increase in lifespan, wich is like rapamycin. also shows better grip strength and darker hair

    In the future i will do my own verision of this information.

    And that is to buy bigger blood donation bags and do it myself. I think 1000ml is the most we can remove before it gets dangerous. Hit low light laser after, with nad boosters and stem cell activators and vitamin k2 for bone growth. you can trigger an massive respons i would assume.

    And if you remove 1000ml instead of 450 on a clinic every 3 months, in a few years that will equal double the health bennefit. And over a lifetime ... damn.

    The optimal would be to remove 1500ml blood, inject NAD+ iv in the other directly after, and shoot a few cc albumin in the shoulder. buut, seems like albumin is needed in higher doses, and that 1500 might be very dangerous.

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    • Fred Cloud you must have missed all the studies posted on longecity, the blood is toxic. When we remove it alone with the mercery/lead/aluminum and senessent cells, new FRESH blood can take its place. Reduced heart attack and mortality by 80%. Best anti aging thing we can due

       

      Also it seems like removing plasma isent strong enough to give a lasting effect, wich removal of blood is.

       

      Buy hey if you wanna spend a million dollars for a years treatment or however many cycles you need to do, go for it

       

      And if your afraid of to low iron, supplement with it

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    • Fred Cloud yeah 1500ml would be recless. Albumin would be needed. AS I WROTE

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    • Fred Cloud pretty strange how you can say that removal of ferritin will create dna damage, when it is ferritin that create dna damage and one of the leading heart disease n cancer.

       

      The iron we get from food arent even the correct one

       

      Your level must be like 20, as afraid as you sound 

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    • Burgundy Summer You have completely misunderstood what I said. I never said donating blood was not healthy, of course it is. I have been donating for years for my health. But you can only donate to a point, more is not better, you seem to think more is better, it isnt. You are saying it is the red blood cells that contains all the aging factors and I am saying it isnt, those are in the plasma. Donating plasma would give you twice the amount of aging factors that you would purge, donating blood only contains half of the plasma. You cant donate enough blood to match the conboy plasma therapy. Thats it.

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    • Fred Cloud if i donated blood, can i donate plasma one month later? can this be cycled? like do plasma in between? my arms would never be able to take that, but maby for a few months to try

      Forgott to quote you the first time, read one below

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    • Fred Cloud RBCs last 90-120 days, not 6 weeks. The rest I agree with. Mr Joules sounds too maverick and way misinformed for his own good.

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    • Burgundy Summer one can safely donate plasma ONLY every 7-10 days. Seriously, read more into this before doing something dangerous and cause more harm than good. And forget about that 1000-1500ml whole blood donation idea. You may end up in ER if not worse.

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    • Burgundy Summer Thanks for the compliment - do what you want. I guess you threw caution out of the window a long time ago. Fred and I tried to warn you but can't save you from yourself. 

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    • aribadabar its obviously not optimal, would need a nurse. 1000ml would not be a problem tho, would be very beneficial to remove 1000 instead of 500

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  • Do you plan on using EDTA intravenously or how do you plan to remove all the metals in your blood? 

    When i was comparing the 450ml vs 1000ml, it was cause i want to create a higher growth phase then 450ml do. its shown that growth factors are released after 450ml donation, stem cells, bone growth. lowering of tgf/tnf. so a double amount would be an even more effect. and i could amplify it with stem cells from low light laser. the removal of heavy metals are a plus. or well not a plus, if not removed we die.

    removal of heavy metals from vaccin with EDTA iv is 90% reduced cancer risk. having this in our blood and body speed up the aging, we age so much faster

    im not against donating plasma, i just dont see the value. do you have any studies showing the health bennefit? how much plasma do they take and what is that equal in blood?

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    • Burgundy Summer I have done 75 intravenous edta chelations from 7 different clinics around the country. I have been at this for a long time. I suspect the benefit from chelation is partially coming from removing iron rather than heavy metals. The higher the iron store the higher the chance of cancer and heart attack and that is also the benefits that chelation therapy gives. See the connection?

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    • Fred Cloud did you ever get problems with side effects btw from the edta?

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    • Fred Cloud i now understand why you think that you dont have much more to gain from blood donation, there will be no toxins left, after edta iv 75 times, haha ! 

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    • Burgundy Summer No side effects. I only did the newer rapid chelation which uses ca-edta that you can push in about 15 minutes versus the slow drip 3 hour old style. It pulls much more heavy metals and takes alot less time. No side effects, just felt great afterwards.

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  • very intresting. i see 20-30ml vials are being sold on indiamart. no matter how much i donate, i will def invest in readl edta cycle the following 20 years. it will be a must to survive. seem to bind to fibrin also. the disease morgellons have exploaded since they started modifing the weather. are you aware of the harvard/bill gates project? spraying nanoparticels in the sky to reflect sunlight. we are basically breathing in murcery and lead every breath we take. remeber what i just said, this will be the leading cause of death the following 50 years. i cant even imagine .... 

    Its also said it will increase drought and rain, it will cool down certen places, like sweden, but will create floods in india. and drought in other places. will not be a even effect. it is suppose to mimmic the vulcano erruption effect = cool down after. wich i notice myself after they spray the chemtrails, the entire city gets few degrees colder.

    So ... it seems like EDTA will be a must use. we dont get autism from iron, so i would assume that lead and mucery is alot alot alot more toxic, dont you think?

    It seems like HEPA filter air purifer can acully capture these metallic nanoparticels. but gotta be a dc motor, ac motor got emf as high as a phone tower, really bizzar

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  • John, If the treatment is spaced 2 days apart, why not just go donate plasma for free? They would allow you to donate at that same frequency. and I suspect they remove the same amount as Dr Kiprov. Also I dont think the albumin replacement gives any therapeutic effect and that seems like the only difference between Dr Kiprov and donation.

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    • Fred Cloud do you know if you can donate both blood and plasma? donate blood, wait a month and donate plasma, wait a month and do plasma, next do blood ? 

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    • Burgundy Summer I think so here in the US, but have no idea what the rules are in Sweden. Here in the US you can donate blood every 8 weeks and plasma even more often. I would donate plasma twice spaced 2 days apart to replicate the conboy therapy. Here in the US you can donate as often as twice in a seven-day period, with at least one day between donations. Which will replicate Dr Kiprov's protocol "Treatment for one person involving two sessions of plasma dilution spaced 2 days apart"

      Do you know what your ferritin level is? You should check that before you make a plan on how much blood you plan to donate.

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    • Fred Cloud thanks for reply. well i think i need to choose one of them, will never have veins to use otherwise if im doing donations for the rest of my life. already damaged veins from nad+ injections. but yeah, intresting ! 

      Yes and i seem to be close to heart disease, 325 in ferritin and the limit is 300-1000 for heart disease. so im just about the line. wich fit perfectly with what i tought about my health due to all the issues i got

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    • Fred Cloud are you dissapointed in the results btw? from plasma. i was betting that this would be the greatest bet we got to rejuvinate. tougheter with mega doses of rapamycin. and hopefully with kutchers "new" monequle. i really hope its not GDF or GHC U or how its spelled. 

      There is no way in hell im saving up money for 20 years to spend it all on this, with this short effect. what a disapointment

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    • Burgundy Summer Katchers topical is most likely GHK-cu but the injectable E5 is not, it is one of the demethylation enzymes like JMJD2/3

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    • Burgundy Summer Your ferritin is at 325? Have you not done any blood donations yet? My ferritin was 400. Now it is 75.

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    • Fred Cloud i really wounder how that one will be possible to get then, if clinic is a must, or if they can sell vials for home use ...

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    • Fred Cloud yes 325, and thats after loosing like 1.5 liter blood in accident, and using fisetin for a year, and still 325.

       

      I did edta orally after that info and 1 donation later im at 220 

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  • I and a friend are part of the Conboy/Kiprov - Alzheimer/Fraility study.  We have had six treatments each.  We each had a methylation age reduction.  Each of our treatments was 2.5l replacement with saline/albumin.  We both felt better for a while.

    My significant improvements are known "side effects", lower blood pressure, liver regeneration.  While I did achieve my lowest methylation age reduction of all experimental treatments tried, the Conboys and Kiprov discount this measurement.

    I am considering additional treatments, based on measurements and am adding GrimAge measurements to the mix.

    In my discussion with the Conboy's, they confirmed that blood donation would be a "cheap and dirty" effective approach.  I am supporting a nanotechnology approach to removing "bad stuff" that may come to clinical trial in 1-2 years.  I am investigating "affinity column" filtration approach to removing "unwanted materials".  I do not want to continue discarding half my plasma long term.

    Now that Ambrosia has been bought by Grifols, watch for products  derived from "young blood factors".

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