The Conboy Plasma-Dilution Treatment is Available Now

Allen It is crazy prices - but that's the $ range what the companies are charging in this space:

Ambrosia was $8,000 for 1 liter, $12000 for 2 liters.

https://www.businessinsider.com/young-blood-transfusions-ambrosia-shut-down-2019-6

Brin Chikovski Ah - I see they've lowered their prices... such a deal!

https://www.ambrosiaplasma.com

Brin Chikovski Considering they pay the donor only a few hundred dollars, they have a pretty big profit margin. My antiaging doc offered me ambrosia plasma and I told him I was taking gdf11 instead and it totally blew his mind.

Brin Chikovski Ambrosia is shut down by FDA already. That info is obsolete.

Winslow James Foster link fixed https://daniellelin.com/2021-06-23-changing-the-landscape-about-alzheimers-dr-dobri-kiprov-private/

Peter I am thinking about doing the same thing. Impressive that you took action and did this, not many people have stepped up and done it. You said you are flying blind, does that mean you arent tracking bloodwork for changes?

Fred Cloud  I'm not sure how to check for blood changes which are atributable solely to plasma loss.  I get the standard CBC panel plus hsCRP and plug into Morgan Levines DNAPhenoage.   I show 14 years younger than my age of 67, but am skeptical.  I do other things as well (exercise, TRE, eat well).  I can't say I have a marker that will tell me anything conclusive although several were a bit better (AST and ALT for examle).  I am trying to discipline myself to cycle through a number of things in a systematic way.  I had to dog off donations last 2 months so will start up again soon, and will get blood panel right before and another about 2 weeks after I offload another 3,000 mls.   BTW, for my weight, under 175, my plasma loss is about 440 mls every two weeks.  Irina C did say that tissue changes with routine plasma removal may take a while as it requires turnove of old cells whch occurs at different rates in different tissues.  I'll be looking for change in grey hair and skin over time, hopefully. She also said she doesn't know how long one treatement will last, but as noted in my last post it seems like at least one month.   I intend to go through another intense donation period then settle down with maintenance plasma removal, maybe ~ 600 mls monthly, and I intend to drive to Orlando and try donating at one of the plasma only centers where I can offload half of my plasma in 3 days and see how that works out.  Finally, and this is even more speculative, there is literature which says that plasma proteins are excreted with the water in sweat, along with environmental toxins. The amount of sweat loss is all over the place, but depending on physical exercise and ambient heat coud be as high a couple of liters a day. I intend to take up the plasma protein sweat transfer question with the right kind scientist as well as sweat volume.  Could be that two or three days of intense sauna and exercise might be another good way way to off load old plasma and might be something good to do in the days following a donation, or between donations   I think this would be a great experiment for a lab equipped to assess changes in DNA expression and proteomics.

Peter Here are the markers that dropped for the Russian biohackers that donated plasma for dilution. There are duplicates of each marker because there were two subjects, so N=2. Big drops in ALT liver, insulin, inflammation like crp and IL-6, very interesting.

Fred Cloud Thanks.   I do need o be systematic.    I track most of these except for IL-6, oxLDL, and IGF-1.  My hsCRP tends to be low already, always <0.5 as does oxLDL and insulin (about 5).  And AST and ALT were fairly good, upper 20s, etc. so reductions weren't so large.   However, liver improvement is expected as Irina said fibrosis was improved.   

Peter By the way, any issues or side effects with the procedure itself? How would you compare it versus donating blood? Just wondering how safe you feel it is.