Sources of dasatinib
Hello everyone,
We’ve received reports from Age Reversal Network members about lower-cost sources of dasatinib. This post is intended to aggregate this information into a single forum post for easy reference and sharing.
The two sources we’re excited about are:
1. MedLab: A pharmacy that will compound dasatinib specifically for your body weight. They offer a customized dasatinib two capsule dose for $225. This represents a one-year supply for most people.
The physician may advise that you take the first dasatinib capsule week one along with the dose-adjusted amount of quercetin and the second dose-adjusted dasatinib capsule week two along with the dose-adjusted amount of quercetin. (Doses are based on your body weight.)
The chart below describes current dosing for senolytic purposes. This requires a prescription and the pharmacy can only ship to Florida addresses. You can contact the pharmacy at 954-400-0560 or email the pharmacist at rxemailbox@gmail.com.
2. International Antiaging Systems (IAS): By July 31st of this year, IAS plans to offer 12 x 40 mg tablets of dasatinib for $99. This represents an average one-year dose that can be individually dosed based on numbers of 40 mg dasatinib tablets you need for your body weight.
For instance, if you weigh 175 pounds, you might want to take 5 of these 40 mg dasatinib tablets to match current dosing suggestions of 2.5 mg of dasatinib per kilogram of body weight. When your weight does not match exactly with the 40 mg dose, members of our private association report taking the additional tablet (making the dose slightly high for your body weight) to achieve desired senolytic effects.
We’ve been told that these dasatinib tablets will be available after July 31, 2019 by logging on to antiaging.clinic (Use password = research, then click the green button saying that you accept the terms and conditions, "T&C", after you've reviewed them).
IAS has pledged to donate 15% of the purchase price from all orders placed on this site (antiaging.clinic) to support human age reversal research. IAS posted this information just a few days ago on the forum here.
While our private association does not have the resources to vouch for these various options, we are grateful that some of our members have independently evaluated (assayed them by an independent analytical lab) them for their personal use, and have then worked with their physician to ensure proper prescribing.
The PowerPoint slide below summarizes dasatinib and quercetin dosing most people are currently self-experimenting with.
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There is a dasatinib related drug caller niotinib that also treats leukemia just like dasatinib. It is being used in a Parkinson’s study because of its strong effect on increasing the part of autophagy that cleans out cellular waste. Niotinib may be useful for anti aging but no direct studies so far beyond autophagy for age reversal.
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are we there yet so not FDA approved or for sale yet?
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WARNING
If you have purchased products such as Rapamycin from the
Anti-Aging store you need to be aware that their check or draft processor
has been hacked. I received an email which had all of my Check
Draft information attached. It was from a hacker who was trying to extort me
for payment through Bit Coin or my personal information would be placed online.
I received this scam email last week. The letter claimed that I had bought Cialis when
I actually bought Rapamycin. The letter had a pdf attachment, which I scanned for
Virus with two anti-virus programs. The letter goes into great detail as to how to pay
approximately 800 dollars in Bit Coin to these scammer. I have deleted the mail and
pdf and am contacting my Bank as to a change in my account. Also did a complete
scan of my computer.
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djmichel I received a similar email attempting to extort a similar amount. They have the correct check payment data, but they got the item purchased wrong. It's really annoying, but hasn't reached actual theft yet. Everyone you've ever sent a check to has the same account data. I'm going to watch my online bank checking report, but nothing else unless something pops up. That and keeping the amount in the checking account close to actual checks written.
Checking is an old technology designed long before many of today's exposures. Best we can do is watch the account and challenge anything out of order.
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I got this email, too. Since I’m female, they didn’t mention Cialis, but instead said “something embarrassing”—lol! I filed an alert on Equifax (which I know will go elsewhere automatically), and notified both Antiaging and Check2Pay, then just let it go. I’m not really worried about this.
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A source in India (New Delhi) is BonHoa Health. They sell a number of drugs including dasatinib at a dose of 50 mg x 60 tabs for $362. Upon searching if this is a reliable company I did not come up with any red flags. I am checking with some colleagues to see if they have heard anything negative about this company. They also sell different doses of dasatinib such as 20 mg and 70 mg tabs. I would imagine that if there were a number of people using dasatinib that shared in one purchase that this would be a very inexpensive source at $6 a tab. Bill Faloon cited Lucidas as a reliable product. BonHoa carries this brand.
See https://www.bonhoahealth.com/leukemia/167-lucidas-sprycel-dasatinib-50mg.html and let me know if any of you has used this company. I will follow-up with any new info I get on BonHoa Health.
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Stephen B. Strum, MD Bonhoa site is gone. Looks like it is changed to https://www.bonhoapharmacy.com/
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Fred Cloud yes Bonhoa Pharmacy has changed site locations. I just received my new supply of Dasatinib. you can also reach them at bonhoahealth@gmail.com. the transaction went smoothly. they sent shipping information when it shipped and I received my shipment pretty quickly. About 3 weeks.
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Good info , Dr; thanx; do you know anything regarding DasaPro--another competitive product?
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Thank you for informing me of another source. It all comes down to (a) reliability of company and (b) how quickly you get the product and (c) affirmation that the product is what it says it is. If you have information concerning this that would help. The cost of DasaPro per their website is $4 a mg. The cost of Lucidas dasatinib via BonHoa Health for 50 mg tab x 60 = $382 is $5 a mg. The latter is shipped out of New Delhi, India. I am not sure where the former is shipped from (UK, Japan?), nor do I know the shipping costs. But I think what is badly needed is a trustworthy independent company to assess drugs made and shipped from countries outside the USA to American consumers. This would lower drug prices and open up a free enterprise and competitive market. And this should be done not just for the relatively exotic drugs we are interested in but many drugs whose prices are just damn ridiculous.
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Hi All. New member to this forum, but not to the overall topic we're all here for...
Question. Where does the 2.5mg/kg dasatinib dosing schedule come from? The mouse studies at 5mg/kg translate into about 25mg to 35mg total dastinib for a human, using the standard Human Equivalent Dose conversion factor of 1/12.3. Some human studies have used 50mg total, and of some have used the full "average" 100mg dose used to treat leukemia.
Looking instead at the effective blood concentrations reached in the mouse studies, I understand the human dose to achieve concentrations in the same area brings us again to about 100mg total.
So far, other than here, the only place I've seen higher doses suggested is on the antiaging.clinic/store site, which suggests 2.5 to 5 mg/kg.
Is this dosage supported anywhere else? Don't want to underdose, but obviously don't want to take a wildly-outsized dose either.
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Robert Rossi I assume most people are using the dose used in the human study.
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(19)30591-2/fulltext
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Karl I note this study still utilizes "just" 100 mg per single dosing, less than the protocol proposed at the start of this discussion thread for someone who only weighs 100 lbs. No study I've seen comes close to supporting any dosage higher than 100mg.
True, we are all experimenters here, prepared to make decisions for ourselves outside the bounds of orthodox thinking, on the basis that the rate of human aging is unfortunately faster than the rate of change of conventional wisdom. But there's still a difference between making an educated guess to balance efficacy against safety, and simply casting caution to the wind and taking gonzo dosages.
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Excellent topic and observation. When I was doing human research on 3BP (bromopyruvate) I created an Excel program that automates this conversion from mouse to human. In the spirit of collaboration and collegiality I share that effort with you here. I am 70 kg and for the mouse dosing at 5 mg/kg my calculated dose would be at 28.7 mg, which is consistent with your post above. What we aspire to in all studies in health is Primum Non Nocere or First (above all) Do No Harm. Therefore, this post by you is of prime importance and should be addressed by those recommending a higher dose. What's the basis?
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Bonhoa informed me yesterday that they will not ship to US or EU. See attached screen shot of their email.
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I am trying to order Dasatinib and metformin from IAS (using antiaging.clinic). They only accept wire transfer from a bank. The problem is that my bank (USAA) requires a physical address for Antiaging (which antiaging.clinic gave me as the name of the account owner) and antiaging.clinic is not providing a physical address. They did provide the physical address for their bank in Hong Kong but not their own physical address. I have written to them twice, once by email and once using their website communication tool, and they have not responded. Perhaps one of the forum members here has their physical address?
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David H I ordered 3 weeks ago and used the address of their bank. Worked fine for me.
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David H I tried to buy DasaPro from the antiaging.clinic but my BofA wire would not complete without a "correct" address for antiaging.clinic. I tried the Hong Kong bank address but the wire would not complete. Still looking for both rapamycin and dasatinib. Even have prescriptions; just no one is selling the product it seems.
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Brook Norton I had the same problem. Someone here suggested theantiaging.store. I tried that and it worked. They did have dasatinib but not rapamycin.
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David H theantiaging.store has been out of DasaPro (dasatinib) for the last few days at least, and I just rechecked - still out. Perhaps the COVID-19 is interrupting supply everywhere. I'm just starting senolytics and rapamycin so don't know how hard it is to get these usually. Flew to Las Vegas to get prescriptions for these. Now I'm all dressed up with no place to go. But will have patience.
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Brook Norton where do you get them in Vegas? I live right outside of Vegas and bought mine from antiaging. Thanks!
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Mel I went to Vegas to get the prescriptions from Dr Julio Garcia. I got the prescriptions, but he too cannot find a source for rapamycin or dasatinib these days. I found Dr Garcia's reference here on this forum. He was good to work with and his thinking is in line with longevity therapies on this forum. He does charge a $50/mth management fee to keep his services active. So that adds up but I will say he is quick to return inquiries and his opinions are appreciated.
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Brook Norton Thanks very much for the intel!
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David H and @Brook Norton: I had the same problem with my bank attempting to wire money to IAS re an order put through antiaging.store.
However, I found their customer service responded quickly, and provided a physical address for IAS that has allowed two successful orders to be processed.The address they customer service at antiaging.store provided for IAS is:
Unit 2, LG 1 Mirror Twr, 61 Mody Rd
The actual address was a longer version of the above, but this was all my bank could fit into the space provided for the recipient address by the Wire Payment Agreement on their computer. Hopefully this does the trick for you. -
Robert Rossi Theantiaging.store (antiaging.store is not a valid address) is showing out of DasaPro (for which I did get a Certificate of Analysis for DasaPro and RapaPro); their Sprycel dasatanib product is also showing out of stock and suspiciously priced at $1K/bottle. I was going through the process of wiring money to another site, antiaging.clinic (entry code "research") and their customer service emailed me instructions on wiring, including how to just send them checking account data. I tried that only to get the reply that they expected to get DasaPro in stock in 2-3 months and would notify me. I'm assuming COVID-19 has disrupted the supply chain for dasatinib and rapamycin, but have not actually read that anywhere.
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