Sources of dasatinib

Hello everyone, 

We’ve received reports from Age Reversal Network members about lower-cost sources of dasatinib. This post is intended to aggregate this information into a single forum post for easy reference and sharing.

The two sources we’re excited about are:

1. MedLab: A pharmacy that will compound dasatinib specifically for your body weight. They offer a customized dasatinib two capsule dose for $225.  This represents a one-year supply for most people.

The physician may advise that you take the first dasatinib capsule week one along with the dose-adjusted amount of quercetin and the second dose-adjusted dasatinib capsule week two along with the dose-adjusted amount of quercetin. (Doses are based on your body weight.)

The chart below describes current dosing for senolytic purposes. This requires a prescription and the pharmacy can only ship to Florida addresses. You can contact the pharmacy at 954-400-0560 or email the pharmacist at rxemailbox@gmail.com.

2. International Antiaging Systems (IAS): By July 31st of this year, IAS plans to offer 12 x 40 mg tablets of dasatinib for $99. This represents an average one-year dose that can be individually dosed based on numbers of 40 mg dasatinib tablets you need for your body weight.

For instance, if you weigh 175 pounds, you might want to take 5 of these 40 mg dasatinib tablets to match current dosing suggestions of 2.5 mg of dasatinib per kilogram of body weight. When your weight does not match exactly with the 40 mg dose, members of our private association report taking the additional tablet (making the dose slightly high for your body weight) to achieve desired senolytic effects.

We’ve been told that these dasatinib tablets will be available after July 31, 2019 by logging on to antiaging.clinic (Use password = research, then click the green button saying that you accept the terms and conditions, "T&C", after you've reviewed them).

IAS has pledged to donate 15% of the purchase price from all orders placed on this site (antiaging.clinic) to support human age reversal research. IAS posted this information just a few days ago on the forum here.

While our private association does not have the resources to vouch for these various options, we are grateful that some of our members have independently evaluated (assayed them by an independent analytical lab) them for their personal use, and have then worked with their physician to ensure proper prescribing.

The PowerPoint slide below summarizes dasatinib and quercetin dosing most people are currently self-experimenting with.

 

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      • I ordered this week and, like Mel, used the address of their bank. My bank (BofA) was fine with that. They wanted to charge me $45 to send in US funds, but they were willing to send in EU funds for free. Weird. Anyway, order is in the mail and it wasn’t difficult once I figured out what to do. Good luck!

        Like 1
        • Paul Beauchemin
        • Paul_Beauchemin
        • 4 yrs agoFri. March 13, 2020 - 7:50 pm
        • Reported - view

        I ordered 3 days ago paid by check order from theantiaging.store 

        Like
          • David H
          • David_Hanson
          • 4 yrs agoSat. March 14, 2020 - 12:55 am
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          Paul Beauchemin That worked!  Thank you!  I have metformin and dasatinib on order from theantiaging.store.   Waiting for rapamycin to get back in stock so I can put in an order that also.

          Like
          • angie4life
          • angie4life
          • 4 yrs agoSat. March 14, 2020 - 11:36 am
          • Reported - view

          David H I’ve always ordered my Metformin from the anti-aging store  and ordered Dasatinib from them when it first came out .  These products are made by ProFound Products , as was the rapamycin I used to get from them . Always a nice company to order from ; just that the rapamycin they carried was found to be a lower dosage than what the bottle claimed . I do hope  the metformin and dasatinib dosages are correct as described , but I get my rapamycin elsewhere now .  Good luck !

          Like
          • David H
          • David_Hanson
          • 4 yrs agoSat. March 14, 2020 - 11:44 am
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          angie4life Thank you for the comments.  Where are you buying rapamycin now?  I am open to an alternative - especially when I don't have to visit an MD.

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          • angie4life
          • angie4life
          • 4 yrs agoSat. March 14, 2020 - 12:22 pm
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          David H I get mine from All Day Chemist, a company I’ve ordered many different things from over the years . Their product is Siromus , and it is a bit expensive, I’ll say . The tablets are 1 mg each , so does make it easy to take the dose you prefer .  

          Like 2
          • Fred Cloud
          • Fred_Cloud
          • 4 yrs agoSat. July 4, 2020 - 5:49 pm
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          angie4life adc has been out of stock for a while now. Why is this stuff so scarce lately?

          Like 1
        • Jerry
        • Steady_Rider
        • 4 yrs agoFri. April 17, 2020 - 3:55 pm
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        For those having trouble wiring funds to overseas sources, set up an account at TransferWise.com; they're easy to work with and cheap to use; should make those overseas transfers easy to accomplish (my last transfer to the AntiAging Store cost me $8.75---if Western Union had been able to do it at all, the cost would have been around $50)

        Like 1
          • ssny. sotero
          • Marketing and Visual Impact Display Specialist
          • sandra_sotero
          • 4 yrs agoTue. May 19, 2020 - 3:49 am
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          Jerry Thank you that is good information to have. I will try TransferWise next time I order.  If I can find a place to buy Dasatinib

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        • Barto Bartino
        • Barto_Bartino
        • 4 yrs agoTue. May 5, 2020 - 3:52 pm
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        Does anyone have a good place to test these compounds?  Alternatively, does anyone have any evidence IAS is sending real products?  

        Like
          • Barto Bartino
          • Barto_Bartino
          • 4 yrs agoTue. May 5, 2020 - 4:38 pm
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          I just received email from IAS stating backlog on products, beginning to see potential scam here?

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          • Brook Norton
          • Brook_Norton
          • 4 yrs agoTue. May 5, 2020 - 8:22 pm
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          Barto Bartino I received Certificates of Analysis for the DasaPro (dasatinib) and RapaPro (rapamycin) products.

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          • Barto Bartino
          • Barto_Bartino
          • 4 yrs agoTue. May 5, 2020 - 11:57 pm
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          Brook Norton I see.  And you believe they’re reputable, according to your past post.  If you happen to know other sources, please let me know.  

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          • Brook Norton
          • Brook_Norton
          • 4 yrs agoWed. May 6, 2020 - 1:27 am
          • Reported - view

          Barto Bartino Yeah, the Certs of Analysis showed accurate ingredients. I cannot find any place that has dasatinib or rapamycin in stock.

          Like
      • Good !! I am a little confused, I was going to start a senolytic therapy with D + Q + F. I was going to do it once a year or at most every 6 months, but in this article this has been said:

         

        * SENOLYTIC WARNING: caution is recommended. Excessive senolytics. Note: excessive can be different between people. Vince Giuliano reports that senolytic signaling is critical for cell renewal: it needs enough inflammation and senescence to indicate regeneration factors, so if it is exceeded in senolytic therapy, it is bad, cell renewal is lost.

         

        www.anti-agingfirewalls.com/2018/09/02/aging-cell-and-tissue-repair-renewal-andregeneration-inflammation-and-the-sasp

         

        More often it is not better. Quote for reason: All Senolytics, so far, look like things that would take once every few years at most. More will not be more effective than that dose: killing senescent cells that you can kill the first time, and will not be useful again until senescent cells increase in volume.

         

        www.fightaging.org/archives/2018/03/how-to-plan-and-carry-out-a-simple-selfexperiment-a-single-person-trial-of-senolytic-peptide-foxo4-dri#caveats- more details

         

        Senescent cell researcher Dorota Skowronska-Krawczyk PhD personally discourages us from having long treatments with senolytic medications. In fact, specifically that they should only be taken for short periods between gaps with longer recovery times.

        Stan Goldfarb has decades of experience in nutritional interventions and applied nutritional supplements. He advises: I think that even 2.5 mg per KG is higher than I want to take, especially when combined with EMIQ (which itself does not have negative side effects up to very high doses). I weigh 137 and I'm going to take 100 mg just once. You should also take at least 10,000iu of D3 to complete apoptosis and not take blood thinners, such as aspirin or omega supplements, as it has been shown to target fat cells for several days before and after. Without doing all of this, a person is simply taking unnecessary risk. When I did my first test of this in 2015, there were some very smart people saying exactly what to do and when. I don't see that now with the current crop of people and it worries me. People have died from overdose of this drug!

         

        Dr. James Kirkland MD recommends not evaluating senolytics on our own at this early stage.

        Senolytics resource:

         

        https://www.aginginterventionfoundation.org/Senolytics.pdf

         

        Similar precautions apply to other therapies. There are many things that we do not know about this new frontier.

        I have found some overlap as well as variations in nutritional supplement programs.

        After reading this, I feel very confused ...

         

        I was going to do Dr. Alan Green's protocol of:

        Dasatinib 100 mg dose for 3 days.

        Quercetin 1000 mg for 3 days

        Fisetin 1500 mg for 3 days.

        But dr. Alan Green says that dasatinib stays in the body for up to 3 hours and here it is said that it can stay for a long time.

         

        And what else if it does more harm than good?

        what do you recommend??

        Like
          • Andrew P K Yap
          • Andrew_P_K_Yap
          • 4 yrs agoThu. May 14, 2020 - 2:05 pm
          • Reported - view

          Pablo Reinaldos López 
          I clicked on the link you provided, 

          http://www.anti-agingfirewalls.com/2018/09/02/aging-cell-and-tissue-repair-renewal-andregeneration-inflammation-and-the-sasp

          it says Page Not Found

          Like
          • Andrew P K Yap
          • Andrew_P_K_Yap
          • 4 yrs agoThu. May 14, 2020 - 2:08 pm
          • Reported - view

          Pablo Reinaldos López 

          If I were you, I won't trust "This person's opinion" and "That person's opinion" no matter what they say their credentials are.

          It's better that you do your own research.

          Like 1
          • Andrew P K Yap
          • Andrew_P_K_Yap
          • 4 yrs agoThu. May 14, 2020 - 2:09 pm
          • Reported - view

          Pablo Reinaldos López 

           

          There is a lot of good information, just Google and read them, the good ones.

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          • djmichel
          • CDR Phx
          • djmichel
          • 4 yrs agoFri. May 15, 2020 - 3:45 pm
          • Reported - view

          @Pablo Reinaldos López  Hi Pablo,  reference Dr. Greens protocol is each of the three, Dasatinib, Quercetin, and Fisetin all taken at the same time on three consecutive days. Do you repeat a week later? I had been following the Life Extension formula of Dasatinib and Quercetin according to weight, on the day one of the first week and day one of the second week.  Thanks for the information.

          Like
          • Joe smith
          • Joe_smith
          • 4 yrs agoSat. May 16, 2020 - 5:23 pm
          • Reported - view

          Pablo Reinaldos López  you have done your homework. You can also check out what Judith Campisi got to say about senolitic treatment and life extension. I recommend not grasping for straws and staying away from senolitic self treatment at least for now.  Also it is pretty clear that keeping systemic inflammation low through calorie restriction, exercise and mostly vegetarian diet are prudent and scientifically proven. Rapamycin is promising but if you go that route work with a doctor and only buy from trusted pharmacy. 

          Like
          • Karl
          • Karl.1
          • 4 yrs agoWed. May 20, 2020 - 9:24 pm
          • Reported - view

          Pablo Reinaldos López Dasatinib has a half life of 3-5 hrs.

          Like
          • ssny. sotero
          • Marketing and Visual Impact Display Specialist
          • sandra_sotero
          • 4 yrs agoMon. May 25, 2020 - 7:10 pm
          • Reported - view

          djmichel I do the Life Extension formula as well.  I have been a member for over 20 years and found them to be the most reliable informaiton. 

          Like
          • Jimmy2
          • Jimmy2
          • 3 yrs agoMon. June 21, 2021 - 4:04 pm
          • Reported - view

          Pablo Reinaldos López Dr. Alan Green's protocol is not recommended for people under 50.

          Like
        • Flavio Ferlitz
        • Retired
        • Florjan
        • 4 yrs agoThu. May 14, 2020 - 8:07 pm
        • Reported - view

        IAS is good and I know they are improving their paying methods; however my country, perhaps the whole EU except for the UK, does not let in medicines with foreign prescriptions- the risk is big trouble. I can't even view the site of the clinic..

        https://tailormadecompounding.com/ is a compounding Pharmacy in Kentucky, but it would not be any good again if you live in the EU. They compound Dasatinib with Quercetin at the desired dose.

        I had started to follow Dr. Green prescription to make a good start, then I would have tried the other interventions later on. All I'm left with here is the avoidance of A.G.E.s via cooking and food choices and trying to exercise.

        So I'm back with the Life Extension supplements, many of which point in maybe even more directions, but I'm left without Rapamycin and Dasatinib. They would have been handy, given that I'm thin and not very good with C.R. by now.

        Also: the updated Life Management Panel has become much more complex. In the EU one can do many tests, but now I'm not sure if ALL of them could be found so easily -as detailed in the Age Reversal Update on the L.E. Mag. of March 2020- to be in the position to be in a study. I can fly over for the tests and participate as taking certain supplements, seasonally carrying out a fast for a few days, but no help from medicines. Well, travel is theory for now, with the virus's unforeseeable end.

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