Making sirolimus cream---Tried to grind a 2mg rapamune pill with a grinder and then dissolve in DMSO to put in cream.

My pill was not ground to a powder.  DMSO did not seem to dissolve it but instead made it stick to container so I had little left to put in cream.  I f you get a capsule of sirolimus to open will it be powder to put in cream???

  I have gotten cream from Tailor Made but they only have weak .001 strength which after using 3 refills only on face I can see no improvement.  Maybe women will not see the same improvement as men because they have always used creams.  Would like to make a strenght of .002 before I give up on cream. 

I have been taking rapamune weekly 4mg first 4 weeks and 6 mg for 22 weeks.  One round of dasatnib abd not sure I am getting results. Maybe I need to increase weekly?

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  • I purchased 10 grams of 99% pure Rapamycin powder for $200 from , who is a rep for Zhejiang Multinpharma Ltd. That's easier than trying to grind up pills. However, I have no idea if the powder will dissolve in DMSO.

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    • JGC rapa powder dissolves well ! 

    • JGC I am not sure if you actually need the DMSO or not. I have tried it both ways and didnt notice a difference. I used the Dr Mark Thimineur strength of 3mg in 4oz. lotion

      By the way, thats a great price on rapamycin. At 5mg a week, that is almost a 40 year supply, right?

      • Laur
      • Laur
      • 3 mths ago
      • Reported - view

      JGC I do not recommend this seller from China:



      Zhejiang Multinpharma Co., Ltd
      Tel: 0086-571-85081802
      Skype: rainbow673614
      Mobile: 0086-159-5817-3572 (WhatsApp) / +86 159 5817 3572


      I purchased 10g for $200. I did the sirolimus dosage test 1 hour after taking 6mg with grapefruit seed oil, and it came back negative. When I mentioned the result to the seller, he recommended I buy higher quality rapamycin for $650.

    • Laur JGC You could try Transuctol as a solubilizer since DMSO will cause irritation in along run even in very small concentration

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