Key Methylation Site discovered?
Participated on a webinar yesterday put on by Vince Guiliano and Steve Buss who post at anit-agingfirewalls.com. They appear to be a couple of guys with a scientific background that read lots of papers and think they have found the key to reversal of aging.
His posting seems triggered by Harold Katchers work and Akshay Sanghavi (Harold Katchers benefactor) was on the call and spoke after the meeting had ended.
Thinks they have uncovered a key is demethylation of histone group (H3K27me2-3) by activation of JMJD3 proteins can reverse aging. I’ll post link to video if he sends it out. Spoke a lot about the role of the spleen and the blood network's role in this.
He made a point that before this can work have to eliminate/ reduce inflammation otherwise possibility of cancer.
Some of the things I recall that activate JMJD3 ARE
Metformin
Rapamycin
Exercise
Sauna
Red or infrared therapy
Vitamin D
Curcumin
And a few others but this was the most interesting-varying oxygen levels via the EWOT (exercise with oxygen therapy) . Cited bow whales, mole rats and turtles long lives due to this phenomenon. Hyperbaric o2 chambers are a step in this direction but EWOT is better for generating variable oxygen hormesis due to get rich O2 levels deep into capillaries.