Key Methylation Site discovered?

Participated on a webinar yesterday put on by Vince Guiliano and Steve Buss who post at anit-agingfirewalls.com. They appear to be a couple of guys with a scientific background that read lots of papers and think they have found the key to reversal of aging.

His posting seems triggered by Harold Katchers work and Akshay Sanghavi (Harold Katchers benefactor) was on the call and spoke after the meeting had ended.

Thinks they have uncovered a key is demethylation of histone group (H3K27me2-3) by activation of JMJD3 proteins can reverse aging. I’ll post link to video if he sends it out. Spoke a lot about the role of the spleen and the blood network's role in this.

He made a point that before this can work have to eliminate/ reduce inflammation otherwise possibility of cancer.

Some of the things I recall that activate JMJD3 ARE

Metformin

Rapamycin

Exercise

Sauna

Red or infrared therapy

Vitamin D

Curcumin

And a few others but this was the most interesting-varying oxygen levels via the EWOT (exercise with oxygen therapy) . Cited bow whales, mole rats and turtles long lives due to this phenomenon. Hyperbaric o2 chambers are a step in this direction but EWOT is better for generating variable oxygen hormesis due to get rich O2 levels deep into capillaries.

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    • Fred Cloud thanks

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  • I would love to know what Harold Katchers E5 ingredient is, did they speculate at all?

    I already figured out what the secret ingredient in his blue gel is but dont know what E5 is.

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  • amazing how little notice this has gotten - seem really relevant

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    • Paul Beauchemin It is odd, no one seems interested. I have been studying Vinces website and emailing him for a year so I am already caught up. Maybe its because the forum has been quiet lately in general?

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