garland I just visited doctor Chipman at the Atlantis clinic in Oldsmar (adjacent to Tampa), Fl. I just walked in on Mondays only) and got more than hoped for. After a general exam and interview, he prescribed Metformin + Rapamycin for 20 weeks. I recommend Dr. Chipman. He is friendly, informed, believes in what he's doing, and is committed to his patients. You can also get young blood transfusions there, NAD intravenous shots, blood analysis and all you need to slow down ageing. $150.

Brin Chikovski  Brin, Thanks for posting this. I think that you have suggested an important way forward. I look forward to reading about your results. Collectively, a ton of $ is spent by users of this site, Testing seems the only way forward. I couldn't find costs for analysis on the site.... perhaps because one needs to sign up first... can you share an approximate cost?

Steve Roedde The cost for the three tests I'm most interested in - purity, contaminants, dose, etc. - is $190.  So - it only makes sense if you're buying a lot at once, like a year's worth or more (e.g. multiple people buy at once).  The other issue is that these things (purity, etc.) can change on a batch by batch basis - so you want to try to get the all the medicines in a single batch.  Screen capture below:

Brin Chikovski Reasonable cost.  Thanks again. Very constructive approach.

Steve Roedde 

Patient 139 Well done. 

Steve Roedde could you edit your gram and maybe milligram numbers. I want to be sure I understand it all. 

Patient 139 Sure. I received 2.26g of rapamycin. That is 2260 mg (2226 1 mg doses). I compounded it with 2  lbs  ( I think it was 905g) (it would have been easier to compound with a kilo, but it came in lbs) of lactose powder. The compounding is important to make the final weight/volume large enough to weigh/measure accurately. Once compounded I had 2260 mg of drug in 907000 mg of powder. Dividing 2260 into 907000 gives ~401 mg of powder (nearly all is lactose) to give me one mg of rapamycin. Because its easier to measure than weigh, I repeatedly weighed a level 1/8 teaspoon (about a dozen times)  . The range was only 10 mg either way of 401  mg.  So, that's what I take.  I think this is right... but have not yet had my morning coffee.

@Steve Roedde  I also bought rapamycin from the AntiAging Store. Because of your posts I requested and received a total refund. 

Jane Pearson , I'm glad to hear it. Sadly, I have not yet received mine:-). I'm still working on it.

Steve Roedde Steve - I recommend you read this book before you get too confident in your supplier of what has been marketed as "medicinal grade rapamycin".  

https://www.npr.org/books/titles/722226878/bottle-of-lies-the-inside-story-of-the-generic-drug-boom

I've interacted with many Chinese suppliers for chemical products and you always need to verify the supply is what it claimed. There are huge variations in quality, purity and contaminants.

In a few weeks I've got lab tests coming back on three suppliers of rapamycin from India and I will post my results here.  

Brin Chikovski , I have read it. Excellent book. Without oversight, regulation and rigid enforcement/punishment, business owners in any country will attempt to profit at any expense. I have not been able to access a company to do testing here . Although a certificate of purity was provided, I consider it meaningless.

However, I have chosen to  be pragmatic. It's only 1 mg of actual material per day. About equal to a single gain of sand. My serum levels were identical to when I consumed 1 mg of "Rappamune" (which I assume is made in the West, but if ,not runs all of the identical risks as contamination/production deficits as outlined in the book with the generic drug-maker in India). So I know what was labeled is  real. rapamycin. I can't speak to contaminants... but there is not much actual weight left for any.

China in particular has an unpleasant history... one thinks of the melamine and milk contamination... with many ending up with renal failure and dozens of children dying. At least in China they have real deterrent punishments for CEO's that offend. In the melamine example...they were executed.

Still.... I trust no one. This includes the FDA and Health Canada and brand name as well as generic suppliers. 

Your point is well taken, well supported, and testing of any supply/batch is the ideal option. I look forward to your posted results...with list of contaminants tested for.

Steve Roedde do you have an extruder to compound thoroughly?

Paul Beauchemin , No, I compounded initially by hand, as directed in a compounding manual I found on-line. the 2.26 g with 10 g of lactose. I really spent time with that. Then added the 22G to 50 g... tons of time with that step too. Finally I put the lot in a table-top mixer , ran it very slowly for 20 minutes with a bag over the bowl to keep the dust down. Given my levels... it seems I got a pretty homogeneous mixture. Most is in the freezer, with enough for a month on the counter.

Steve Roedde Wow, I am partly impressed and partly discouraged. I live in NB and was going to send anything to Maine because I have been told there is a high chance anything sent direct will just get stopped. Your lucky that the US mainly is concerned with specific issues and as for the rest, the US gov't is perfectly happy to let civilians kill themselves. I just see your message now. mrrflwllng891@gmail.com Thank you in advance for any help. As i mentioned I have wanted to do this for a long time and the process is a little overwhelming. I will check my email when I get up in a few hours. Thanks for messaging me !

Patient 139 , Dan, Thank you. You are kind. Your comment is deeply appreciated.

Steve Roedde I appreciate everything you've done with this. I used the 50% off that you helped get to use two more bottles from them. I hope it's truly 3.25mg per tab now, but I still have doubts after you posted your test results.

Steve Roedde - Hi Steve . I live in Canada and I am searching for a reputable place that will ship to me. Any help would be really appreciated.

Steve Roedde _ I read the posts about AAS and I am happy I came back here to look the blog over again. Rapamycin is something I have intended to get for a year now and it is the unknown that has held me back !