Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate.
I just wanted to see if anyone has experimented with urolithin A and what effects they noticed.
I've speculated combining it with PQQ and exercise to enhance mitochondrial biogenesis.
No, but I have it coming in. I will be experimenting with 500-1000mg for an extended period of time assuming absence of side/adverse events. Though, based on what we know of the safety profile, I’m confident that I shouldn’t experience many.
I’ll keep you posted. It should arrive in the next week and I will follow up in a months time.
I've been on 1 gram of urolithin A for the past 4 weeks and subjectively I notice a decrease in inflammation and improvement in sustained energy.
I have autoimmune disease so the improvements in inflammation is quite impressive. The energy improvements don't feel stimulating rather than a youthful energy that is sustained- at least with my experience.
Beyond the literature and subjectively urolithin A has the efficiency of drugs. It's quite profound.
I currently take J-147 as well which has shown to improve mitochondria function. Taken together they have a synergetic effect on energy and inflammation. J-147 taken on it's own greatly improves cognitive function, but I do not notice the body energy as much.
Please contact me if you have any questions!
Also - has anyone found any tests (eg. microbiome tests) that can tell you whether you have the right microbiome that allows you to process ellagic acid into Urolithin-A? Only about 40% of people seem to have this ability (from the studies I've read) - so it would be really nice to know if you are one of those people....