Preparations for self-treating COVID-19

JGC Thanks really appreciate the reply and info. It took me forever to get a shipment of Dasatinib from Beacon Medicare Limited, Dhaka, Bangladesh but it finally came thru. Well worth the wait though 30 x 100mg for $220 + shipping. 

Gary Gilley Hello, I would like you to help me.
How about beaconpharma with dasatinib? is trustworthy?
have you tried it already?
What symptoms have you had?

Pablo Reinaldos López Yes, I had no problems with them at all. Only email communications though, but very responsive. It took me about a month to receive the delivery. They take care of customs on their end and I didn't have any problems on my end. Have not used the product yet though. First started with D&Q August last year, then again mid December and I'll be doing my 3rd with this one fairly soon. So far, no side effects whatsoever. Also do weekly Rapa. They only take wire payments but use this link for payment which is much cheaper than a bank. Don't know where you're located but on my end (USA Maryland) it's $50 for an international wire. They don't give you any choice with shipping. For US customers they only use EMS - $65 additional

Gary Gilley. so you've already done two cycles, one in August and the other in December ... Have you noticed beneficial effects, on the skin, on your body with those two previous cycles? 

Do you know of someone who has tried beacon before and is happy?

Pablo Reinaldos López Yes I have, totally anecdotal of course. Some with skin, and areas I've been experiencing pain at for a very long time have completely vanished. I stress anecdotal because I'm 74 and I've been throwing the kitchen sink at it so to speak. Ozone insufflation, NAD+, GDF-11, Fiestin, Rapa & D+Q and lots of supplements.

August 2019 I used Morgan Levine's excel spreadsheet to determine biological age and it's telling me I'm biologically 52, and that was before I started using Rapamycin, Senolytics (D+Q), NAD+, Fiestin etc.

So I'd be disappointed and perhaps a little surprised if I don't get a much better score when I retest again in a couple of months. 

Pablo Reinaldos López No, I don't know anyone that's used Beacon before and is happy.

Gary Gilley 

I'm 76 to be 77 in August. I take 2500mg metformen daily. Take a lot of supplements as well. Still trying to lay out a plan. 

Staffan Olsson 

https://www.wired.com/story/how-un-miracle-drugs-could-help-tame-the-pandemic/

This is article about the history behind the idea that metformin might be beneficìal in managing Covid19.

Steven Jacobs I don’t think the final word on Zithromax is in. Zithromax has properties beyond being an antibiotic and it may be its anti inflammatory property that helps.

Just as hydroxychloroquine likely helps as an anti inflammatory.

Karl Steven Jacobs  Zithromax is a senolytic - there is a video I posted in the senolytic thread describing that effect

Paul Beauchemin 

Paul,

Thanks greatly.

Apologize for too many words. Trying to lay out concept. Trying not to be political in a politically charged field that involves government denials and lack of focused action. Trying to encourage a: "Do something now is possible belief." The recent Congressional Act is not a plan. It is an Emergency fiscal initiative that likely isn't going to deliver near term mid or long term results. It is immediate response in panic; not credible planning or full perspective.

It is interesting that the USA leadership left and right politic continues to ignore that we have no National Anti-aging Plan (NA2P). Our President and Congress just pushed out over $2 trillion to remedy the economic impact and COVID-19 threat; yet, no NA2P exist? In fact the average life span of US citizens has been decreasing for over a decade. Logically; an NA2P would have a sub-task of prevention and cure of new viruses (that includes COVID-19). The conclusion is there exist failed national planing for health care and sustaining humans' lives.The conclusion is also that absent a credible plan; prioritization of funding and budgeting leaves humans vulnerable because national resources cannot be credibly directed toward the goal of increasing human life spans. A clear example of failed national fiscal health allocation is the challenge of countering the COVID-19 threat. Our military receives $billions every year; so to does many other agencies; all of whom are charged with national health. Oddly, looking at the Federal State and local budgets; no where exist a $billion to solve the mystery of human aging. No NA2P; no budget; etc.

Our national intelligence budget is huge and there are many upon many dedicated individuals making it the global best; this COVID-19 thing isn't a surprise. It is a communication, listening, and appropriate action failure. That issue must be fixed.

As far as I'm concerned; human anti-aging science is proven by a few prime examples. That is enough to declare mission and assign it. The statistics that equate to 100's of years of proven human life extension success isn't available; but, extrapolations are tools of current science. Extrapolations are statistical useable. They are used all the time in defense weapon system designs. There are increasing commercial products on the market; especially, for the human brain; but, our nation still has no NA2P. From the policy and management perspective; a government NA2P should aid the competitive and capitalist initiative; but, there should also be in-government focus to catalyze attainment of the goal that human life spans increase in a fast manner. Human life span increase is very important to the fundamental existence of humans. Technology is more focused on shortening the time emergence of super intelligent machines (the Singularity); than, extending human life spans. COVID-19 is a global threat to human life.

Remedy to COVID-19 as well as human aging, is necessarily global. Governments have no national plans or budgets or policy for NA2P's. Planning, put together properly; COVID-19 prevention and cure is just another subtask in a, in our case,  NA2P. One really doesn't have to care what such a human life plan is officaly called; however, the fact that no plan exist indicates that political and buracratic leadership has failed. We collectively have to face that fact and fix the problem.

Conclusion: perhaps age reversal should have national (even also global) policy and planning initiatives. Logically; also we must work toward lobbying and initiate a letter writing champaign for causation of competent government NA2P establishment. A few $billions into all phases of research would be easy to achieve by a simple Executive Order or government leader Directive or Congressional Act. Actually, even the Security of Defense could establish one for our military IAW Directive or Executive Order. Orders are done all the time. The President can direct by Executive Order. Simply put; The President could just direct that all health Agencies and the Dept of Defense give 2% of existing budget toward establishment of the new national organization with mission to vastly extend US citizens life spans. The new organization would have mission for establishment and funding of a new agency with national responsibility for establishing and execution of the NA2P. This new organization could then give 1% back to revelant organizations where it makes sense for execution of assigned subtasks of the NA2P. Since Federal dollars flow down to States and properties and possessions; those organizations also establish missions and execute them IAW policy and directives. Point being; it is credibly possible to quickly establish and focus a new government organization to quickly establish and assign and part back missions to achieve establishment and execution of the NA2P. Is not credibly increasing human life span a high priority in the face of the emerging singularity and virus and bio attacks spawned by global warming, natural evolution and known (also unknown) military threats? The same "colors" of money that the US Department of Defense is structured to manage would conceptually work; e.g., all categories of research, development, production; logistics; etc. Humm? Model fiscal apparatus on the Defense Appropriations Act? Our nation spends $billions of defense $ on training and keeping alive soldiers and well; but, has no defense department sub-NA2P to a national plan. The money is there; it just isn't mission focused or planned or overseen or credibly directed and therefore cannot be managed or directed responsibly. The fix for that is reasonably self-evident. Create and assign mission. assure mission accountably. 

There are many on many government and commercial labs and organizations; but, no national focus to direct use toward tasks for extending human life spans.

The FDA & others need not apply. Take $ from them and give back in an assigned manner and measure performance against actual delivered and focused assigned tasks or remove it for malfeasance.

To establish credible human life span increases; therein government is already most of the human & fiscal resources and facilitation.  All new government organizations have growing pains. It starts with mission assignment. Think Space Force. All it takes is a Directive; Executive Order. The details will be worked out later. The money is already there and can be carved out as discussed herein.

Since we are talking $billions (likely $ trillions over time) credibly focused on serious increases in human life span; we are acknowledging a vital national need (extending human life span to 100 years, 200; 300; etc).; then, logically prevention and cure of COVID-19 is a small part of that mission assignment. COVID-19 is mutating and re-infecting. Congressionally politically flash flooding & throwing $trillions into the market is not fiscally responsible or accountable in good management principles or policy. Better than staying in denial; but, loose. 

The proposed mission, organization for creation and execution of the NA2P could bring needed organization and planning into place. That is desperately needed. 

In Department of Defense weapon systems acquisition policies, rules & regulations makes sure that the prototype isn't intentionally destroyed by fail-bad testing (with some minor exceptions for final prove out)  Pseudo approaches for human clinical trials are unethical and slow down product delivery by years. Logically; improving better human software simulations is mandatory to quickly increasing human life spans and proving out new drugs, herb mixes; etc. National policy must increase human trials; but, not damage those in the trials.

We cannot wait 100+ years before declaring small victories in increasing human life spans. We must make the case we have enough progress to commit to a NA2P and mission assignment; e. g., an all the boiler plate stuff to make success happen institutionally and deliver credible results fast.

Our nation needs a Manhattan Project like focus with serious resources and highest priority. As discussed; start up is just Executive decision. Start up is doable. The resources are there; the mission is doable; but, only, if credibly organized, and mission assigned, and resourced. Actions require organization, assignments and planning. Results must be scheduled, focused, and progress monitored, reported and measured. Best business practices are wise and necessary. Not political gamesmanship.

No NA2P = no sustainable remedy to increasingly decreasing human life span. In the mid term (not long term); it is super intelligent machine service life and upgrades versus human life span. There are plenty of predictions on when the singularity will be in full fruition; it is already in early phases. Yeah; scary.

COVID-19 is just a wake up call. Telling old citizens to die in interest of defeating COVID-19 and supporting the economy is foul minded.

Global warming will deliver new virus and bacteria threats to humans. The NA2P must have proactive subtasks to stand ready and act quickly in prevention and cure. Point being; humans are in a continued active emergency and must have sustainable active defenses and remain in preparedness. Again; COVID-19 is just a wake up call.

We have got to get Bill Faloon, Elon Musk, and many credible others speaking & proposing government policy and pushing sane government mission; functions and organization. Congressional Acts must be created and signed into law. Start up $billions (even $trillions) are there for many initiatives and amazing advances; but, only if we take initiative. The capitalist market must yield affordable results and sustainably continue the fight against human aging. From that perspective; COVID-19 is just one in a continuing line of new and old threats to human life span and those threats must be met to extend quality human life span increases. 

From my simple view; death is just wasted good human adventure on planet Earth. Heaven or whatever will take care of itself. I'll spend my life in care and concern for others. That said; I have freedom longest.

Lets commit to serious life span increases and seeking to never die. Set serious goals and attain them. The proposed NA2P must be based on goals and successes toward attainment measurable and forecast. Therein is a new economy with human life span increases payback. That is sound economic policy. That is not welfare; it is just applied common sense and good government and commercial management and business. management. It is personally wise.

Interestingly; we have to take up the policy, planning. budgeting, organization, resourcing, facilitating; etc. missions; including law changes challenge. That must logically be part and parcel to seriously increasing quality human life span mission success. Yeah; it appears to me that the Age-Reversal and Rescue Elders folks (and many others) can have a voice.

In perspective; the senolytic testing and products are part and parcel to the greater NA2P initiative. one of many on many task in the NA2P. Planned, budgeted, funded. facilitated, resourced, assigned, and progress reported and measured on a scheduled delivery. Capitalism and government working together for credible results soonest.

It isn't a chicken and egg issue; it is a:" Go get the chicken and eggs issue; here is the (NA2P) basket & use our own each hands & brains." Less government limits and more open doors and $. Credible policy, planning, mission and focus; etc.

Obviously, you and many others have the wonderful brains and guts for taking action.

Somehow, we must cause the NA2P concept initiative to yield credible results. 

Change it up; add to it; whatever needed to make it happen. 

Your thoughts?

Sincerely,

Steve

JGC I stand by my statement that a drug with dangerous side effects may or may not work.

Karl All drugs are dangerous to some degree - metformin, rapamycin and Dasatanib are just a few people on this site experiment with. One of the most toxic drugs we take on a daily basis is Tylenol. Plaquenil is much less toxic than that drug and has been proven for decades. My wife has taken relatively high doses for 15 years. The dosage given in these experiments over 5 days is within that range and has a negligible chance of side effects. Making statements that its dangerous is unhelpful.

Paul Beauchemin as a physician I understand every drug has side effects. And I’m glad your wife has done well on Plaquenil. But Plaqnenil is a far more dangerous drug than Tylenol. 

Karl  problem with most docs is they know very little out of their own specialty

The Rheumatologists know it the best - attached is a quote from Dr Daniel Wallace.

Karl My wife was diagnosed with an autoimmune disease in 2010 (after 20 years of health problems without a diagnoses.).  The first thing her Mayo Clinic - Jacksonville rheumatologist did was prescribe Plaquenil.   He emphasized the safety of taking Plaquenil.  The only issue he mentioned was a small possibility of eye problems from long term use.  Our two sons were also on a form of chloroquine  or hydroxychloroquine from 1984 to 1987 as a malaria preventative.  My company's doctor stressed how safe chloroquine was.  We lived in Gabon for 3 years because I was a petroleum engineer helping maintain an offshore oil field.

Paul Beauchemin thanks for letting me know what’s wrong with all doctors.

Karl With all due respect, the medical profession has brought on my skepticism by their own actions. In 50 years of dealing with doctors I have observed a strange combination of hubris coupled with ignorance of information outside what was taught in med school. Most doctors don't have time or inclination to read lots of scientific journals outside their expertise. Maybe you do, I don't know you. My self and family have suffered lots of unnecessary pain due to poor advice from doctors who refused to admit their ignorance. I'd like to sue the medical profession as a whole for this negligence.

Paul Beauchemin when you use the phrase “with all due respect “, it usually means you don’t respect. Thanks for the disrespect and stereotyping me. I hope nobody does the same to you.  Oh, and I am a white male if you want to make further judgements.

Karl Everybody's wrong everybody's right
Someone must be wrong when someone else is right
Everybody's wrong everybody's right
You tell me that I'm wrong
Then you tell me that I'm right

Can't stand it, right?

Paul Beauchemin I also have many complaints about doctors and the medical system.  But the doctors here deserve our support and admiration.  Let's not scare away the good ones.

Mark Thimineur 

you mentioned in the past you were changing your protocol going to a much higher dose of cycling rapamycin. What affects or conclusions have you noticed In regard to your health on this new protocol? If I recall you were taking points .08 kg per body weight up to .15 kg per bodyweight. Thanks 

John Mcgough I've completed a trial of 0.08mg/kg up to 0.17mg/kg. Since I am 70kg this was 6mg on the low and 12mg on the high. In my individual case, I percieved problems with the higher dose in terms of decreased stamina and energy. Labwork was not much changed. It did not feel right. Taking a one month hiatus right now and, after 15 days, feel very good again. I'm going to trial a radical change in rapa dosing which requires a lengthy post. Once I obtain preliminary results (about 6 months) I'll provide the info.

Mark Thimineur thanks for the update. I’ll be curious to hear how your new protocol works. I find your information useful and I use it in deciding my own experimenting with dosage. For  instance you mentioned at the higher dose in your first year you notice the greatest benefit so I’m experimenting with keeping my dose at 7mg  without cycling. I am 75 Kilos and interested to see if it increases my lymphocytes. Thanks again.

Mark Thimineur 

As a patient of Dr Green I was wondering.

You mentioned a aompounding pharmacy that provides rapamycin capsules for $1.00 per milligram and dastinib for $3.50 per 50mg capsule

Would you mind providing the name so I can have Dr Green write a script

JGC 

Thank you. Looks like a good idea: https://clinicaltrials.gov/ct2/show/NCT04326725, https://abc7.com/coronavirus-drug-covid-19-malaria-hydroxychloroquine/6079864/

Steven Jacobs 

nicely said 

Steven Jacobs 

Good Again!

Money in envelopes- ha - a good laugh😅

The national plan will likely come out of the military. It’s how they think. And it’s likely there already- to assure protection of the military and key government officials. Like taking control of N95 mask supplies and respirators...

But They won’t find the cure. That will come from outside the box of their thinking. And it will be ignored or poo-pood for a long time. 

Yes, interesting times.

My son lives in Taipei. Before that in Beijing. Very into what the government’s have done. Not much on the treatment side. But in Taiwan all cell phones are tracked for movement. They have used cell phones to track backwards the movements of covid patients and then scrub things. Taiwan was very early in blocking ALL Incoming Chinese from both Hong Kong and China. They got burnt by the SARS virus and others and where highly prepared to act quickly. They also have very advanced hospital treatment for respiratory viruses.

cheers

BobM

BobM 

Bob;

Perspective is always important. 1st step in any planning. Our elected leaders appear surprised at. COVID-19; but, reading all the news encourages one to recognize that some US Generals closed bases and instituted quarantine in Jan. Generals always brief up the chain of command. Our highest leaders knew.

Going beyond that; it is reasonably good sense to recognize that this virus is serious, contagious and deadly. Comparing death rates to the flu makes zip sense. They should find more credible vaccine to the flu as well. The left and right politic are just playing at pointing fingers. That is the art of political distraction in cover up of the collective leadership failure to protect the military and civilian populations. The CARES Act is more CYA than a plan. In fact of fact; it has no credible plan unless it has a National Anti-Aging Plan. Just my humble opine. I've seen military plans for bio, viral, chem and nuke attacks.  CARES isn't one.

Just my opine. No offense to anyone that sees situational awareness differently. More opines than one is always wise.

This disease won't go poof! Plan on a long journey.

Salutes to all the champions seeking preparedness and longest lives.

Go team!

Ha! Write leaders and demand more than they are doing.

Later,

Karl equivalent dosage for 60 kg person is 15 gm metformin and 3.6 gms of HCQ

That would surly kill me!

Karl 

Dr. Anthony Cardillo claims that:

Hydroxychloroquine + zinc = all of his severely-ill COVID-19 patients became symptom-free in 8 to 12 hours

Hydroxychloroquine + nothing = nothing

Are you or any of the other docs that you know thinking of prescribing this stuff to severely-ill COVID-19 patients?

https://abc7.com/coronavirus-drug-covid-19-malaria-hydroxychloroquine/6079864/

Florin Along these lines, it is being bandied about that Quercetin is also an iontophor like Hydroxychloroquine and might be able to be used in its place.

https://www.ncbi.nlm.nih.gov/pubmed/25050823

Florin don’t really care to argue with you if your source of medical information is local abc new.  I would ask you to look at that story to see if it really passes any scientific review.

Karl 

Of course, I realize that it has a ton of problems (and even in the best of times, most medical research is supposedly junk anyway), but if we're really at war here, we don't have the luxury of waiting for the outcome clinical trials; we just gotta try MacGyvering this thing.

Dan Nave 

An IC doc in the Netherlands claims that quercetin + zinc is giving good results with his CODIV-19 patients.

https://www.longecity.org/forum/topic/108038-protecting-from-coronavirus-supplements-therapies/page-31#entry889761

Florin 

The challenge is to live longest ever. Research China's longest living human. Beat his record. Set a positive example. That said; don't take poison to get on the tail of a comet. Serious leaps in life span length will come most quickly from a seriously funded National Anti-aging Plan (NA2P). Credible plans allow for immediate term as well as long term and everything in between tasks. Trump could direct some % of CARES funds go to a NA2P. Hummmm??? Even 3% of $2+ trillion is a serious start up. 

Steven Jacobs 

What anti-aging plan would the NA2P use? Why isn't that anti-aging plan being already used by the NIH or NIA? What's going to prevent the NA2P from turning into just another version of the NIH or NIA? How will politicians even hear about the NA2P proposal and why would they take it seriously?

Florin 

Thanks greatly for asking.

One must keep a sense of humor and hope for a favorable lottery win. I do write elected leaders. None appear to be able to read unless serious money is attached.

One would think that a measure of government success would be how long their citizens live? If isn't necessarily how long. Note: Some were encouraging the old to die of COVID-19 as a duty to the nation. How bloody stupid?

Changing focus and redirecting any government to increase human life spans is apparently complex. Organized religions have posed death as a ticket to heaven. Living in Alabama offers observation that many want to die as part and parcel to ritual. Looks like a Earth life ender to me. 

Logically; an NA2P has to be created and be knowledge based.

The Department of Defense gets all phases of research $ (e.g., known-known; known unknown; unknown known; and unknown-unknown); but, for some lack of left or right politic reason; human life span increases are not that important of a research area. Smallpox is pretty much eliminated; polio is reappearing. One would think that if the global objective was to eradicate COVID-19 was on the table; WHO would be assigned the job where other nations are inadequate. Fix any mis-management issues and inoculate our own IAW our. own plans. Our commerce is international (global); so, logically; a global initiative makes sense. Being an economic isolationist appear to not meet the challenge of increasing human life spans; or eradication of human diseases; including COVID-19.

Why doesn't human life span increases qualify for all phases of government research in a credible plan? Good question. Maybe political leaders are more interested in collecting money that visionary leadership. Sorry; no one can blame any political party--they make off with the $ all the time and still haven't figured out this: "Serve the people thing." 

To achieve anti-aging; we must demand it.

Ha! What happens? The politics of distraction: WHO gets fiscally cut; no pressure on a global COVID-19 eradication. Not playing politics; talking management science and mission success and assignments and funding--all the serious things that credibly solve serious problems.

We are  victims of political science and the art of distraction and have been for decades. Solution?: "Wise up; demand more." No NA2P; no vote or champaign $. Fire em all. Start over.

Funny. At 76; it appears that politicians simply want $ and to stay elected until death. We need to pick better and insist on more. Politicians will flip on a penny for a vote. Best we pick them better and hold them to full account. Obviously; increasing human life span isn't a mission assigned or funded; or whoever is assigned is hiding. Everything starts with mission assignment & $. Then; plans and accountability follow.

Never trust government is how to keep any plan on track. The NA2P has to be transparent and accountable to really smart and wise and very capable leaders who are held to account to the people; vice political yes people. It has to have metrics and measurable goals and milestones and tasks and subtasks and schedules that are strategic planned (active & updated with feedback loops). It must be funded. It ain't.

The US Department of Defense (DoD) sets up Program Executive Officers (PEOs) and over arching plans and organizations to manage complex military systems. Integrated Product Teams (IPTs); when well managed; help integrate and increase do-ability with bottom ups and top down data. I'm not advocating military; but, recognizing the Manhattan Project worked (in this case; it could end up with some, yet undefined, overarching organization with mission $, and plan and resources).  Yes, with human life spans decreasing and global warming a serious threat; it appears wise to assign a mission to seriously increase human life spans. A NA2P would follow IAW mission assignment.

Interestingly; COVID-19 is just a subtask. Hummm??? $2+ trillion in an unplanned subtask? Forget the politics; is that credible management?  What about all the other diseases in the human aging bundle?

Hard truth is that super intelligent machines will out live us and be more capable. Research existing war and future war machines for your own awareness-scary. Research the predicted time of the Singularity. Guess what; it is already emerging in bits and pieces; including IAW supporting policy.

So here we are; no NA2P at all to reverse human aging; or even for that matter stabilize it at its increasingly low life span level. Go figure?

Looks like to me that a bucket (COVID-19) isn't planned and loosely in a trailer in front of a truck and neither the truck or the trailer are funded. credibly and there is no clear driver or destination of driver or human life span increase mission assigned. In military terms: "The human life span is broke; it ain't getting better. Management is confused, disoriented, disconnected and lacks focus.

Solution:

Assign mission and make someone accountable and provide resources."

Take a $% of COVID-19 funding allocation and set up Manhattan like Project. Later pull more COVID-19 $ into NA2P mission where appropriate.

OK? Propose something more doable or work making this better. We have to start somewhere. That simple. 

Again; think Anti-aging and human life span increases management and mission assignment and credible planning and funding; etc. Not politics.

Leave politics out to do your own each and collective analyses. Mission attainment of longer human life spans is essential to sustained human existence on planet Earth and elsewhere.

Sure that is complex; but, so what? No NA2P? No good reason to not have mission assigned or planned and not credibly budgeted, resourced or funded. 

Situation critical! Broke.

Is something seriously messed up or what?

Other opines (pro or con) welcome.

Thanks for your response.

Steven Jacobs

Steven Jacobs 

How about this for a NA2P mission statement: the NA2P's mission is to enhance health, lengthen life, and reduce illness and disability.

Florin 

Posted some more thoughts on NA2P. Now encouraging more discussion on "adaptation" where adaptation includes handicapped as well as higher performance mission(s). Point is that the military is already invested in adaptations in pursuit of an advanced soldier as well as aiding the injured. As such; human life span increase mission needs to include adaptations.

Adaptations in that case deserves an NA2P section of it's own with cross links to specific diseases; e.g., mechanical legs, hearts, etc. Bio brain to electronic circuit and vice versa. Logically, that mission will see growth; especially, as the Singularity matures and humans compete with super intelligent machines.

Some would dismiss this AI type reality; but, a small amount of research may change minds to include this science and technology as part and parcel to increasing quality as well as length of human life spans.

Suggest taking a look at predicted time emergence of the Singularity and when global warming becomes human habitat destabilizing.

That type of timeline research brings reality to the need for a NA2P: now. Average human life span lengths are still decreasing. Not only are humans dying too soon; they are also becoming less fertile. Point is that an NA2P is urgent. It isn't just about COVID-19.

Much more to consider in pursuit of NA2P mission statement clarity.

Encourage more dialogue and voices.

Thanks for your comments.

Florin 

Given national all political party failure to pursue anti-aging or recognize that COVID-19 would be subtask therein; situation presently broke. A NA2P; logically, anti-aging awareness needs brought forth to top decision-makers. Given existing lack of existence of mission or NA2P; mission is conceptualized herein as Manhattan like Project leading to formal organization and/or reorganization. Starting out as an Over-Arching Directive and Anti-aging mission assignment that allows pulling resources from NIH, NIA, FDA; many others and aligning as necessary to put together a NA2P to manage mission assigned. Point is; got to start somewhere. Presently USA Anti-aging mission is profoundly zip. Broke.

Florin 

Maybe add the word: "progressively" before "enhance"? Got to somehow emphasize serious schedule and overarching mission.. Just about every health organization can say they seek to enhance health, lengthen life, and reduce illness.   As such; mission has to be dedicated and overarching. There is presently no NA2P.  The effort has to very straightforward and clear in a way to make the need direct and meaningful. I have some very religious friends that tell me I don't understand the teachings of the Bible or any religious order; e.g., humans are supposed to suffer on Earth and then die. Accordingly; there is much selling required. Health organizations are like all bureaucracies; mission protective. If the mission isn't clear in a way that makes it unique; they will all say they already do it. Fact is that there is no Federal, State, or local NA2P. Alabama political leadership appears to not only want to control all women's bodies; but, also for its citizens to die IAW their Governor's and Legistature's and preachers; etc., beliefs. Many other states fall in the same view of situational awareness; e,g., accept death.

I'm opposed to death and prefer a longest tour on planet earth as possible. Why end the adventure early?

Not seeking to be critical; just observing that selling life everlasting on Earth is counter; to the brain washed logic of the millennia.

It is an interesting thing to try to understand why people are so willing to accept short life spans as justified by an act of god; faith. For sure we presently die and for sure human life spans are decreasing in length; so one would think that would be very alarming to everyone? Not so.

As such; a mission to increase human life spans is interestingly a hard sell.

Facilitation is another area that needs mission clarification. That is testing labs, computerized human simulations, hyperbolic chambers, real estate; etc. University courses need established. 

Pseudo testing isn't done with expensive military systems. They cost to much to develop. The FDA instance on pseudo testing is immoral and unethical. Humans have unmeasurable worth. One can be sure that creatures of the Singularity won't be use salvaged via testing. The FDA allows humans to die as quality test control of drugs. No developer of military systems destruct test as a required condition of trials. true their are drop test for crash worthiness; but, that is a minimum and highly controlled situation. Obviously, that points need of clinical trial policy changes. There is a lot. of. work presently on quantum computing; however, that is mostly associated with energy (nuclear energy and bombs). Go figure? Logically, there is critical need to increase human life spans via modeling human conditions. When "Overarching" is fully understood: it clearly must direct some of those resources toward human modeling for express purpose of disease prevention and cure and eradication as well as facilitation and adaptations necessary to execute the human life span increasing challenges.

The proposed NA2P is complex. It must be executed with mission teeth. policies and laws must be created.

Having an over-arching mission to credibly extend human life spans is a complex mission. It; however, is a must do if humans continue to exist. A credible NA2P is mandatory for success.

The NA2P is a Human Life Span Extension mission management tool that must be strategic in nature (constantly updated & with feedback loops) and must be under clear charter and mission to over-arch existing health efforts. 

Logically, insurance markets will emerge.

The human life span increase mission is very complex. Very urgent.

20% of the Grey Beard (military term for old knowledge base really gifted smart people) that get COVID-19 die. That is a huge loss of Human Resources. It cannot be tolerated. It is a huge lost to families and family structure. It cannot be tolerated. Period. Eradicate COVID-19; period. Be prepared and eradicate all diseases of aging. Plan for adaptations. Execute human life span increases missions.

Situation: broke. Both the right and left politic clueless.

Queueing theory would predict that their will be times of mass leadership cluelessness. Time to speak up. The fact and the fake press are both quiet and so too are too many leaders should be alarming.

Anti-aging is not fringe; it is urgent and forward good sense thinking. 

Yet; the mission to increase human life spans is a credibly a "do it or die sooner" situation. That is all human situation. 

Note: True preparedness requires planning and funding and a state of readiness. COVID-19 demonstrates those basics were not and are not now in place. Serious look at the CARES Act demonstrates that such mission of increasing human life spans or eradication of COVID-19 are not included. It is reasonable to observe that global warming and environmental pollution for profits will increase the emergence of new virus; bio, pollutants, toxins, etc. Situational awareness and readiness are broke. ZIP planning. Not good.

As Pogo once said: "We have met the enemy and he are us."

Yes; more mission clarity is necessary. The masses (that includes us) cannot be prepared unless there exist credible: mission, planning, function, funding, budget, resources, etc. Since preparedness for COVID-19 (it will be back) still isn't in place and their are no plans to eradicate it; an NA2P is still needed (COVID-19 is sub-task). Think military sets, kits and outfits (SKOs). Not saying everyone needs a full bio or chem suit (MOP thing). Ha! Maybe a sugar cube of vaccine will do? Point being: a NA2P could make human life span increases actually happen with goals like 100 years, 200 years; etc. Deliver by an assigned and accountable mission higher quality and longer human lives; and, cause it to happen via known schedule vice hollow politics.

Your thoughts?

Steven Jacobs

P.S.: Sorry for so much verbiage; trying to be clear. There is a lot to the sought after NA2P and its directive, and empowered mission.

Steven Jacobs 

How about this: the NA2P's mission is to cure, prevent, or manage all diseases.

This discussion needs its own separate thread.

Florin 

It likely needs two or more.  Preparedness comes from planning.

Mission  for NA2P is another.

Organization; functions; etc., could also be added as threads.

I agree with your comment. Part is here; more is elsewhere. 

Karl 

No zinc, no effect.

Fortunately, a few H+Z and zinc-focused clinical trials for COVID-19 have already been started.

https://clinicaltrials.gov/ct2/results?cond=&term=hydroxychloroquine+zinc
https://medicalxpress.com/news/2020-04-world-first-trial-benefit-intravenous-zinc.html
https://clinicaltrials.gov/ct2/show/NCT04351490
https://clinicaltrials.gov/ct2/show/NCT04342728

Florin 

Yes; that is good. 

Wonder when and if some of the approaches to anti-aging will be investigated as preventive measures.  Logically, this virus isn't targeted for eradication and no clear leader is assigned with responsibility; e.g., it will likely be a sustained threat to human life. That observed; successful anti-aging is a key to survival from all diseases.

The proposed NA2P would hasten remedy. COVID-19 isn't going to go poof. COVID-19  is with us until globally eradicated and there is no plan or apparent intent to globally eradicate it.

The studies & clinical trials are good; but, I haven't seen the details to make a guess on how good. Some clinical trials are not worth the investment of time or money from the get go. Some are done with the intent of selling drugs vs wise use of zinc; etc.,; e.g., some trials may be being done with intent to disqualify use of zinc. Interestingly, many clinical trials were done to disqualify fish oil in order to sell drugs.