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Re: Sources of dasatinib @Pablo Reinaldos López you have done your homework. You can also check out what Judith Campisi got to say about senolitic treatment and life extension.…
- Joe smith
- Joe_smith
- 4 yrs ago
- Senolytics Discussion
- Reported - view
Re: EPIGENETIC MUTATIONS, REVERSAL TO NORMAL Do the the rats receiving the elixir treatment live longer?
- Joe smith
- Joe_smith
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin self-experimentation @Larry Shortening telomeres do affect gene expression as Steve Horvath pointed out as counterpoint in the article’s comments section. Hence telomeres are not just an odometer of our cellular aging.
- Joe smith
- Joe_smith
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: FDA to stop pharmaceutical companies from producing Nad+ and Dastinib Dasatinib is still on the list of approved drugs https://www.accessdata.fda.gov/drugsatfda_docs/nda/2006/021986_022072_SprycelTOC.cfm ? with respect of nad I believe fda doesn’t allow for pharmacy…
- Joe smith
- Joe_smith
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @David C do you guys have any blood tests before and then during the treatment?
- Joe smith
- Joe_smith
- 4 yrs ago
- Senolytics Discussion
- Reported - view
Re: Glucosamine instead of Metformin and Rapamycin? @Zisos Katsiapis with rapamycin you need to have comprehensive lab work done before you start and then ongoing every six months. This needs to be reviewed by doc.…
- Joe smith
- Joe_smith
- 4 yrs ago
- AMPK Activation
- Reported - view
Re: Should we be taking oral NR/NMN? @Van I watched videos. The last is is especially good as it also provides a guideline on trying one drug at a time and observing results before proceeding.…
- Joe smith
- Joe_smith
- 4 yrs ago
- NAD+ Restoration
- Reported - view
Re: Glucosamine instead of Metformin and Rapamycin? The issue with Berberine is that it is just not as widely studied as Metformin and not fda controlled. It is probably ok and little bit beneficial for ldl-c and high blood sugar.…
- Joe smith
- Joe_smith
- 4 yrs ago
- AMPK Activation
- Reported - view
Re: Glucosamine instead of Metformin and Rapamycin? I don’t think your #1 holds true. Efficacy of rapamycin for life extension is much higher and per dr Kaeberlein in reasonable doses rapamycin is no more dangerous than aspirin.…
- Joe smith
- Joe_smith
- 4 yrs ago
- 2
- AMPK Activation
- Reported - view
Re: Hair regrowth @Mark Thimineur microneedling is quite effective especially when combined with topical minoxidil. Should see new hair sprouting in a couple of months after commencing the regimen.
- Joe smith
- Joe_smith
- 4 yrs ago
- 2
- General Discussion
- Reported - view
Re: Oral NAD; wasting our time and money? To be fair to Dr Patrick, she said that pro-inflammatory senescent cells when exposed to nad+ precursor became cancerous, she said that further studies are needed to find out if overall cancer risk…
- Joe smith
- Joe_smith
- 4 yrs ago
- General Discussion
- Reported - view
Re: Restore NAD+ Level without NR or NMN @Staffan Olsson Couple of comments. First I’m not surprised that antioxidant study you are referring to shortened a lifespan. I think antioxidant theory of aging just doesn’t have support in the…
- Joe smith
- Joe_smith
- 4 yrs ago
- 1
- NAD+ Restoration
- Reported - view
Re: Cycling Rapamycin with NAD+ Precursors So what’s the conclusion here? Has anybody tried taking rapamycin with nad+ precursor in intermittent fashion? That is taking nad+ precursor not together with rapamycin but rather waiting e.g.…
- Joe smith
- Joe_smith
- 4 yrs ago
- 4
- Rapamycin Discussion
- Reported - view
Re: Restore NAD+ Level without NR or NMN Here is the link to her research https://cdn.shopify.com/s/files/1/0029/5449/4052/files/Undoing_ageing_poster_2019_-_Correct_size.pdf . The doc has the test results but is not specific with respect…
- Joe smith
- Joe_smith
- 4 yrs ago
- 2
- NAD+ Restoration
- Reported - view
Re: Berberine @Karl both berberine and Metformin can be considered diabetic medicines as they have similar good efficacy. Just because you can buy berberine otc in the us doesn’t make it any less effective for…
- Joe smith
- Joe_smith
- 4 yrs ago
- AMPK Activation
- Reported - view
Re: Berberine @Karl i take both Metformin and berberine. Check out this study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059038/ and there other as well. They are actually complimentary.…
- Joe smith
- Joe_smith
- 4 yrs ago
- AMPK Activation
- Reported - view
Re: Restore NAD+ Level without NR or NMN @Zisos Katsiapis Nicola Conlon agrees with your conclusions and started Nuchido. Check out her blog, supplement and presentation during 2019 undoing aging.…
- Joe smith
- Joe_smith
- 4 yrs ago
- 1
- NAD+ Restoration
- Reported - view

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Joe smith

Joe_smith

SF Bay Area

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Joined: Wed Apr 08 05:30:51 UTC 2020

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