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Re: Fisetin ( + quercitin)
And they used human adipose tissue explants (voluntary liposuction!) to see if results translated. They did!
- Rob8311
- 6 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin ( + quercitin)
@David Michel Not sure that trying to notice how you feel is the best course. I just had blood taken and want to see liver values change (ALT, AMY, ALKP) because fisetin helps with liver oxidative…
- Rob8311
- 6 yrs ago
- Senolytics Discussion
- Reported - view
Re: Rapamycin Side Effect
@are we there yet Astaxanthin, Zeaxanthin, and Carnosine (eyedrops and capsules) really help. I've stopped the progression in my 16 year old dog with those supplements.…
- Rob8311
- 6 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Side Effect
@Don More vitamin C, and maybe also colloidal silver. I've resisted using it because it's supposed to be a fad, but I have met too many people who rave about it.…
- Rob8311
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Side Effect
@Don The half life of rapamycin is about 60 hours, so a weekly dose suppresses mTOR1 but gives mTOR2 (the one you don't want to suppress) time to recover.
- Rob8311
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Side Effect
@Don Not too scary, since rapamycin's original large dose effect was to suppress the immune system.
- Rob8311
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Rudi Hi Rudi, Thanks for info about IAAS. I absolutely agree with the need for measurement data. I am going to be doing some experimenting with senolytics both with myself and with my aging pups.…
- Rob8311
- 6 yrs ago
- Self-Experimentation
- Reported - view
Share, Please

I've seen a post or two of someone talking about taking dasatinib + quercitin. I've even seen a detailed dosage schedule and mention of a list of compounding pharmacies that I can't find.…
- Rob8311
- 6 yrs ago
- 5replies
- 275
- 3
- Self-Experimentation
Rapamycin Side Effect

Just read a recent addition to Dr. Green's site. I'll just post part of what he says. I don't get the impression he thinks it is a reason to stop treating, but important to be aware of.…
- Rob8311
- 6 yrs ago
- 67replies
- 1474
- 3
- Self-Experimentation
Re: Rapamycin Cost
@angie4life Not sure if I feel better. Under a ton of stress trying to help one of my dogs keep the use of her rear legs (disc problems), and maybe starting to deal with it better.…
- Rob8311
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@angie4life You are rolling the dice to get this without a prescription. Make sure they have an actual physical location. Probably get their stuff from China - not necessarily bad,…
- Rob8311
- 6 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ozone8 Wow. Those two could own your heart! These two have captured mine.
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Dennis $398 for 90 mg. It's made by a subsidiary of Pfizer, the maker of rapamune. You need a prescription but that's not impossible. Mermaid provided a list of doctors: http: //health.…
- Rob8311
- 7 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Dennis I got the impression from Dr. Green that he thought Walmart was a less chancier option, but don't quote me. I'm just saying I wouldn't go by that unless you ask Dr. Green.
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ozone8 Post revised by Maximus (thanks!) to reflect accurate dosages of 0.1 mg/kg, 0.05 mg/kg, and 0.025 mg/kg for the first U of WA study high dose, first U of WA low dose,…
- Rob8311
- 7 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Dennis Since I am nearing retirement I would be interested in where you bought sirolimus online, and how you have confidence in the seller.
- Rob8311
- 7 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ozone8 If Poco is 5 kg (say 10 pounds) that would be 0.5 mg at the higher dose of 0.1mg/kg. If you can get close to that you could try a protocol of MF instead of MWF which might allow for a bit of…
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Maximus Please correct my answer to Ozone8! The dosages I gave are exactly 10x too high!!!
- Rob8311
- 7 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ozone8 Did you get the age reversal update? They mention some reasons why some people might not benefit; e.g., you are very fit and into CR. Also, I think you have to be older. Dr.…
- Rob8311
- 7 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ozone8 You should doubt my figures! I'm off by a decimal place - sorry!! 0.025 mg/kg, 0.05 mg/kg, and 0.1 mg/kg (the one my dogs are on) . Glad you were watching.…
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Mermaid I'm glad. Much of this info isn't easy to come by. Rapamune is the Pfizer drug, which is very expensive. Sirolimus is the generic, and what I am using. Walmart or Costco are close to the $2.…
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
[Dosing edited/corrected by Maximus Peto at Rob8311's request] @Ozone8 Don't mess with rapamycin unless you study it first because large doses are harmful. Sirolimus comes in 0.5 mg and 1 mg tablets.…
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- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Ted Have been taking NR for a few months and not noticing much. My energy is pretty good, though. Apparently it's best to take it in the morning on an empty stomach.…
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
Addendum: My insurance, after charging me for the first month, gave me a 90-day supply at no copay! They reevaluated after a month as part of their internal process.…
- Rob8311
- 7 yrs ago
- Self-Experimentation
- Reported - view
Status of Studies

Would like to see more info on the status of studies, like if they are closed and underway, or when they expect to report their findings. The dasatinib/quercitin study should be done by now, right?…
- Rob8311
- 7 yrs ago
- 1reply
- 162
- 2
- General Discussion

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