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Re: Fisetin to Clear Senescent Cells
My first reaction to Novusetin (Drs Best or Swanson) was wonderful. I felt absolutely fantastic for a few days, almost like a drug, and I suddenly had the ability to stay up all night without…
Rob8311
Rob8311
2 yrs ago
3
Self-Experimentation
Reported - view
Re: Dasatinib
@Jack Silberman Rapa is very important to me, worth the $212 I pay at Ralph's pharmacy using GoodRx for 2 months @7 tablets/week. I have not found it to be a substitute for exercise at all, though.…
Rob8311
Rob8311
2 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin ( + quercitin)
@Arizona Kid Send me a message - click on pic circle.
Rob8311
Rob8311
3 yrs ago
Senolytics Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Rob8311 Just ordered a test from The DNA Company (damn webinars!). Maybe I'll be able to see if I am somehow triggering the wrong gene. Not an endorsement because I haven't tried it yet,…
Rob8311
Rob8311
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@ripeideas That sucks. I have my own insomnia problem, not the same as yours I know. THC/CBN gummies worked great, for a while. Sounds like you are using an overall health approach instead of…
Rob8311
Rob8311
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@ripeideas Swanson has quercitin anhydrous (out of stock right now) and there's also quercitin EMIQ.
Rob8311
Rob8311
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@ripeideas I don't think anyone really knows yet what frequency is best. One idea is to base it on how long it takes for senescent cells to accumulate after a treatment.…
Rob8311
Rob8311
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@ripeideas I read a study on Quercitin showing that it does not directly induce apoptosis but opens several pathways for apoptosis, presumably ripe for a senolytic like fisetin.…
Rob8311
Rob8311
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin ( + quercitin)
@Arizona Kid Sure
Rob8311
Rob8311
3 yrs ago
Senolytics Discussion
Reported - view
Re: Rapamycin Cost
@Billy Smith Some ideas... Cold Laser Therapy can really help with this. It helped my dogs so much I bought my own laser for $5K, and I use it on my dogs and myself. Best purchase I ever made.…
Rob8311
Rob8311
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin ( + quercitin)
@Andriy Urenov Hi Andry. You have a lucky dog! My laser uses 637nm for red but the range is 600-660nm. Near IR (800-860nm) is better for most applications,…
Rob8311
Rob8311
4 yrs ago
Senolytics Discussion
Reported - view
Re: Fisetin ( + quercitin)
@Andriy Urenov Doing OK, thanks. Still grieving. They did fine on fisetin. You can also give fish/krill oil (with breakfast and dinner) and anti-inflammatories like curcumin (prefer Theracurmin).…
Rob8311
Rob8311
4 yrs ago
1
Senolytics Discussion
Reported - view
Re: Dasatinib
@Rob8311 Plus, get them off kibble and on a balanced diet.
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@Rob8311 And krill oil gelcaps at least once a day (Costco has good ones).
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@Joe smith Sirolimus (Zydus). To be honest, I would start giving your dog 50 mg Quinogel (SwansonVitamins) with every meal, milk thistle for liver (Life Extension has great caps),…
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@Paul Beauchemin Well, they lived to 16-1/2 and 17, when few Boston Terriers make it past 14. Since dogs age 6 or so times faster than us, I don't think you need a week to protect mTORC2.…
Rob8311
Rob8311
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Dasatinib
@ssny. sotero Check out the Dr. Green website I mentioned for fisetin dosing. Also, why not contact him bout the dasatinib? It's worth a shot. Or see if BonHoa is offering it still.…
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@Pablo Reinaldos López When cells go through apoptosis they disintegrate, no comeback. Senescent cells are older cells that are put in that state by the body.…
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@ssny. sotero Sirolimus 6mg per week, per Dr. Green, if based on weight that is his calculation, not mine. No, I think the two treatments work in entirely different ways and do not conflict.…
Rob8311
Rob8311
4 yrs ago
2
Self-Experimentation
Reported - view
Re: Dasatinib
@ssny. sotero Yes, I use both. At age 68 the use of both is clearly appropriate. Dr Green says one should begin senolytics at age 40-45. Offhand, I don't know what age is recommended for starting…
Rob8311
Rob8311
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Dasatinib
@ssny. sotero They are not mutually exclusive. Rapamycin keeps your body from over-regulating itself and in the process inhibits senescent cell formation,…
Rob8311
Rob8311
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Dasatinib
@ssny. sotero If you are doing 100 mg daily for three days for two weeks every 3 months that's over a year's worth. I am a patient of Dr. Green. I went to see him in NY for my exam years ago.…
Rob8311
Rob8311
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Dasatinib
@Mel It might be worth another try. I ordered shortly after someone else who was told a prescription was required, but no prescription was ever discussed with me.…
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@JGC That's good, because the drug sheet says it's fine with or without food. One less substance to agonize about when to take, and good for those with sensitive stomachs.
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
Re: Dasatinib
@JGC Any particular reason to take dasatinib on an empty stomach?
Rob8311
Rob8311
4 yrs ago
Self-Experimentation
Reported - view
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Rob8311
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