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Re: Fisetin experimentation one year (reposted as topic for info purposes) @Dean W. That quote is from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067934/
- Dean W.
- Dean_W
- 7 mths ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Brian Valerie I see that Amazon sells one pound jars of Long Pepper seeds for about $25. I found that an extract of the seeds with methanol yields 99.3% piperlongumine:…
- Dean W.
- Dean_W
- 7 mths ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Brian Valerie Thanks, Brian. Good to know someone has looked into this. I always wondered why Life Extension thought black tea theaflavins would be a substitute for dasatinib.…
- Dean W.
- Dean_W
- 7 mths ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @garland Thanks for the suggestions. I will try it once every 2 months for awhile. I am a bit leary because a recent study found a slight increase in epigenetic age after taking fisetin with or…
- Dean W.
- Dean_W
- 7 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @JGC All good info. Personally, I have not read about anyone getting flu-like symptoms and I have experienced zero change after completing 3 days of fisetin at 30 mg/kg a day.…
- Dean W.
- Dean_W
- 8 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Allen DeLaney @Brian Valerie We may be assuming the wrong action of Fisetin. People have written since 2011 about Fisetin "killing" senescent cells by making them targets of the cell cleanup…
- Dean W.
- Dean_W
- 8 mths ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) Allen, I am not criticising your attempt, I am just stating that it could be Google that is at fault. I find, in my state, they are wrong about 10% of the time.
- Dean W.
- Dean_W
- 8 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) Thanks. BTW, I have found that Google Map street addresses are often incorrect. They really need to improve that aspect of their Maps pages.
- Dean W.
- Dean_W
- 8 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Allen DeLaney said: Walmart house brand supplements contained little or none of the compound listed Allen, can you please provide a link for this study?…
- Dean W.
- Dean_W
- 8 mths ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Allen DeLaney Back in 2020 I was already aware that fisetin had poor solubility in water. I looked it up and found that the value was 0.151 mg per ml. This means that 1 gallon of water (3785 ml)…
- Dean W.
- Dean_W
- 9 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Allen DeLaney Thanks for the reply. I suspect they are all made in China by contract chemists in relatively small batches since we represent a small market.
- Dean W.
- Dean_W
- 9 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Allen DeLaney Please tell us what brand(s) of liposomal fisetin your are using. Did you get it on Amazon or where? Also confirm when you take the 2500 mg;…
- Dean W.
- Dean_W
- 9 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Staffan Olsson Thank you for sharing your info with us! Just a few more questions. Because fisetin is not very soluble I am wondering how much olive oil you use to dissolve or mix your 1 day dose.…
- Dean W.
- Dean_W
- 11 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Staffan Olsson Thanks for the info. What time of day to you take the fisetin/olive oil mixture? With or without food? I am just curious to see what might make a difference.…
- Dean W.
- Dean_W
- 11 mths ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Staffan Olsson Do you open up every capsule and mix it with olive oil? I have tried that at 20 mg/kg using Swansons and felt no difference.
- Dean W.
- Dean_W
- 11 mths ago
- Senolytics Discussion
- Reported - view
Re: Taurine in general health as well as in mitochondrial health Since these replies are 8 months ago I wanted to point out this article from June 2023 which reports that Taurine supplementation in mice resulted in an 18% to 25% increase in life span!…
- Dean W.
- Dean_W
- 1 yr ago
- 1
- Ideas
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Jay Orman All good to know. Sharing our experiments will benefit all. I always thought of the D+Q protocol as being stronger than fisetin. Yet still no changes noted? Hmmm.…
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) After taking the Mayo protocol for my weight (1.5 grams fisetin for 2 days, every 6 months) I felt no changes. I am 73 and must have some senescent cells.…
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) Yes, 20 mg/kg for 2 days is what I have been going by too. But I see no results! No difference in the way I feel. (I am 72.) Do you? (Everyone in this conversation should share their age, please,…
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @John Ramos David C. is referring to his [3 grams for 3 days every 4 weeks] routine for taking fisetin. This is from his many detailed posts above starting 2 years ago.
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @David C Thank you for that very interesting update. I will increase my fisetin dose next time I do my semi-annual course. If I see results I will most likely take it every 2 months.
- Dean W.
- Dean_W
- 2 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @David C Thanks for confirming your post from 2 years ago. Are you still seeing the great effects that you mentioned back then or has that tapered off?
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @John Ramos From what I have read no senolytic will "clear out" all senecent cells. It is far from 100% efficent, more like 25 to 50%. Also different cells in the body are not affected by the same…
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @John Ramos Care to divulge where you get Metformin cheaply? Can you get it without a prescription?
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @John Ramos Yes, that is the milligram number I use too. But John C. said he is taking 3 grams a day for 3 days (see his post from 2 years ago). 3 grams is twice as much as I take so I was wondering…
- Dean W.
- Dean_W
- 2 yrs ago
- Senolytics Discussion
- Reported - view

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Dean W.

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Joined: Thu Dec 03 17:36:59 UTC 2020

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