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Re: Rejuvant? @Chuck Frasher my solution is to make a smoothie with the day's dosage of CaAKG and some protein powder and drink it at times through the day, like before and after exercising.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Rapamycin - progress so far @Arizona Kid. Will do. I should have lab results in late October.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells Here is an excerpt from the article on the grapefruit juice effect on sirolimus. I didnt realize that the effect begins within a few hours of ingesting the juice. I thought it was faster than that.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @David H Okay, that explains Dr Green’s reasons for moving to biweekly dosage. I just cant find any scientific basis for cycling the timing of D&F to coincide with a low blood level of rapa.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @David H Yes, I did see that. I respect his opinion but dont know the rationale.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @David H Is there a rationale you know of that suggests it is better not to take D&F the same week as rapamycin? I cant think of any benefit. I alternate D&F but I take rapa weekly.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far Besides reducing rapa dosage at the point you experience side effects, or adding days between doses there may be a third option to reach the maximum dosage without side effects.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @Van This is extremely interesting. Do you have a link to Blagasklonny's paper where he discussed this? I apparently missed it on Twitter. Does Dr Green discuss this somewhere?…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved @Jonette Brook you could send a message to Max Peto and ask for assistance with this.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: wrinkle reduction My impression of the effect of topical rapamycin on my skin is that it is effective but superficial. The elasticity of skin on the back of my hand is greatly improved from a snap back time of 4…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved @Jimmy2 I only asked about Richard Brook.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved The Administrator told me that Richard had not been blocked.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved A search for Jonette and Richard Brook brings up the following: https://www.egabiotech.net/, https://egabiotech.com/ https://www.foxonlaw.com/scam/law-military-supply/
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved @Jonette Brook Since my post was a sincere compliment for Richard Brook's achievement, it is puzzling that you would reply with such hostile insulting sarcasm.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave I haven't been able to find any study that shows the amount of increased absorption of fisetin that is provided by piperine or Bioperine. I spoke to a scientist at Sabinsa and he guessed…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC Here is the link to the paper you mentioned that was presented at the American Aging Association yesterday. (Titled: Senolytics reversibly improve metabolic health in nonhuman primates).…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics @Fred Cloud Corrected. Important Distinctions.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics @Katy Weston Here is the document I quoted from: https://pubmed.ncbi.nlm.nih.gov/32671763/ And here is another one of interest: https://www.ncbi.nlm.nih.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics @Katy Weston It seems that this particular senolytic protocol might not be beneficial for you. In a PubMed document it is suggested that increasing autophagy could in fact be harmful for some…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Longevity Achieved @aribadabar, it looks like the telomere length percentile ranking corresponds to that of the average 30 year old. Pretty impressive.
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: HGLA and GLA as Senolytics Thats a good question. My reasoning is that I dont want to go very far above what I believe has been shown to be safe when it comes to dosage and frequency of senolytic protocols.…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @JGC ,@Fred Cloud. Is there reason to believe that fisetin and/or quercitin are beneficial taken daily in addition to the D&Q&F protocol?
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland ,@Dan Nave @garland,@Dan Nave Another D&Q&F protocol with Bioperine. I am very afraid of dasatinib side effects. While the effect of piperine on dasatinib isnt clear,…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC and @Dan Nave This clarifies the mechanism: "The mechanism of action responsible for the bioavailability enhancing effect of Bioperine® is because a small amount of piperine stimulates the…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Senolytics with DGLA and GLA? @Dan Nave Thats good advice. We really don’t know if there might be other unknown side effects. I am somewhat comforted by an article published in 2012 in Lipids in Health and Disease which states:…
- chuck stanley
- chuck_stanley
- 3 yrs ago
- Self-Experimentation
- Reported - view

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chuck stanley

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