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Re: Fisetin to Clear Senescent Cells
@Van What's his definition of young? I'm 50 and certainly my doctors describe that as young. :)
- Jack_Black
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Kelly K To explain my comments above the reason I suggest not using Q at all regularly is the reasoning that it is chronic non-fatal toxicities that promote cancer.…
- Jack_Black
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Van So it's now F+D ? Wow hadn't heard that. Interesting.
- Jack_Black
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Kelly K Just be careful how regularly you take Q. When it was given to mice every day it reduced their lifespan by a lot. It has a toxicity and the benefit seems to derive from occasional…
- Jack_Black
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
Decided to do a tolerance test before going ahead with fisetin. According to the info in this thread I might go for a dose north of 2000mg based on my weight for a hit and run treatment (92kg and…
- Jack_Black
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: The problem with this forum and others as I see it
What works for me might not for others, not medical advice etc; I started taking the exercise supplement (A)AKG about a month ago. I seemed to get more energy when exercising after about 3 days.…
- Jack_Black
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: CD38, NAD+ Deficiency, and Senescent Cells
@Fred Cloud I did a bunch of searching and found a reference to fisetin targeting adipocytes too. Now it seems adipocytes and the liver are the two places where M1 macrophage interactions with…
- Jack_Black
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
@Staffan Olsson I agree I also *think* I have darker hair, and I have some very slight hair regrowth. But by the time I noticed this AKG and NAD boosters are also in the mix with spermidine so I…
- Jack_Black
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Apigenin Increases Muscle Mass And Improves Muscle Function In Both Young And Old Mice
@JGC I agree a bioavailable form would be most welcome. The current tablets are likely a waste. I eat fresh parsley regularly these days with the idea getting *some* of the molecule from natural…
- Jack_Black
- 4 yrs ago
- General Discussion
- Reported - view
Re: I don't know why this great supplement is not talked about: alpha-ketoglutarate
Sometimes hard to tease these apart but I felt improved exercise performance after taking AKG for 3 days. Effects wore off after 5 days without the supplement and back after 3 days again the second…
- Jack_Black
- 4 yrs ago
- General Discussion
- Reported - view

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