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Re: Rapamycin and shingles, is there a connection @Marcus Asaro Thanks Marcus, yes I'm back on it now and will also try to get the shingles jab in about a years time. I'm not too worried about the shingles if I can get a vaccine but I am worried…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin and shingles, is there a connection @Krister Kauppi Thanks for this Krister, it is really helpful and I used the link. I realise I am now taking quite a large dose of 4-6mg weekly with grapefruit (the twitter data had this does…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin and shingles, is there a connection @Marcus Asaro Marcus thank you for replying and also for pointing out my mistake. It’s 6mg per week not per day. I would still value your opinion on whether this with anti TNF is immunosuppressing…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Are these issues related to rapamycin @Dan Nave Thank you this is most helpful. I wish I'd had the shot before the shingles but at 53 its probably still worth getting. Not sure how long after shingles would be the most useful time but…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Are these issues related to rapamycin Thank you all. I don't have any side effects but my worry is that overly suppressing the immune system, even if at a subtle level, may increase the risk of cancer. Any thoughts?
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Are these issues related to rapamycin Thank you. I think I’ll reduce my dose and get the vaccine
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Are these issues related to rapamycin No I hadn’t had the vaccine. Sounds like a good idea. I think I may have been over doing it and tipping into immunosuppression rather than modulation
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Are these issues related to rapamycin Thank you, that’s what I feel. However I’m still suspicious of the shingles. I am very well, none of the usual risk factors like stress or another infection and I’ve had a severe attack.…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Rapamycin and shingles, is there a connection
I have a question about the effects of rapamycin and whether it may play a part in my attack of shingles. I am 53 and have been self experimenting with 6mg a day augmented with grapefruit juice for…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- 6replies
- 172
- Self-Experimentation
Are these issues related to rapamycin
Hello there and thank you to all on the forum, I am finding it enormously helpful directing my self experimentation. I am 53 with a string family history of dementia I am trying to stave off.…
- Dr Sian Klerk
- Doctor and self experimenter
- Dr_Sian_McIver
- 2 yrs ago
- 30replies
- 502
- Self-Experimentation

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Dr Sian Klerk

Dr_Sian_McIver

Doctor and self experimenter

London

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Joined: Mon Feb 14 09:57:52 UTC 2022

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Using a pseudonym as still practicing here in the UK. Contact me via this site for any interest in self experimentation in the UK