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Re: Possible negative response to oral NAD+ @Richard Sapp Why snake oil? Both seem to work and have well-understood mechanisms of action as far as how the body converts them to NAD.
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Need more emphasis on diet @Dan Here's a podcast with Dr Perlmutter (author of "Grain Brain") on the Bulletproof podcast, titled "Why You Desperately Need Carbs": https://blog.bulletproof.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Need more emphasis on diet @Dan "The goal is to take pot shots at plant foods " This statement is really bizarre, and hyperbolic in the extreme. Literally no one I know is recommending avoiding plant foods in their entirety.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Need more emphasis on diet @Dan Please read Dr Perlmutter's book. It's about far more than gluten. Grains are not a necessary part of any diet. The evidence is overwhelming that in the long run, they are bad for your brain.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging? @Dan I don't think I am misunderstanding you, though. If you're saying, "here today, gone tomorrow" -- well, no. The parabiosis experiments in mice make it very clear that young blood has the…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Phosphatidylcholine IV Fascinating; I'd never heard of an IV for this before. Do you have any links?
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: NAD+ and Cancer @Dan I agree with Dan on this; I would not worry about this at all. The risks of NOT increasing NAD levels seem a lot higher than the risks of increasing them.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Possible negative response to oral NAD+ Dan, the more I've looked into increasing NAD+ levels, the more I've come to prefer NMN over nicotinamide riboside. It seems to be a lot more effective at actually raising NAD levels.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: LDL-C reduction with diet and supplements (no statins) @Paul Tozour It's interesting that these results seem to match with https://healthcorrelator.blogspot.com/2009/12/total-cholesterol-and-cardiovascular.html
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: LDL-C reduction with diet and supplements (no statins) Maximus, I think your niacin supplementation is great. But the more I look into cholesterol, the more I think it's one of the least important things to be looking at -- and total cholesterol in…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave As long as they make it into your intestines, they should work fine. The alternative is to do what Dave Asprey and Joe Mercola discussed on the Bulletproof podcast,…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @BobM Alcohol is the opposite of an anti-aging supplement. I'd cut it back close to zero if you're actually trying to live longer. There's some data showing that alcohol may have a very mild…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @karl kuffner I am generally a fan of LEF supplements but since the Senolytic Activator is just quercitin plus some theaflavins, you're probably better off buying the quercitin by itself from a…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC This is awesome data, JGC! Thank you!
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin JPA, check out the Bulletproof Radio podcast where Dave Asprey interviews Joe Mercola -- episode 588. They discuss creating a customized suppository to supplement with things fisetin and NR…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging? @HRS It's not just about the blood cells. Blood also includes things like GDF11 -- Google Steve Perry's research on this. As far as transplanting young bone marrow from accident victims -- not sure…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging? @Dan That's not really the case, though. Blood carries all sorts of hormones, enzymes, and other chemical messengers, as well as stem cells. GDF11 in particular seems to have a dramatic impact;…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Need more emphasis on diet @Dan Sourdough bread? Anything with bread in the diet is not a good idea. https://www.drperlmutter.com/about/grain-brain-by-david-perlmutter/
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: KLOTHO and GABA for Brain Enhancement Thanks for the recommendation, JGC! I just added this to my supplement regimen.
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: Whole genome sequencing for $700-750? Brian, I recently downloaded my DNA file from AncestryDNA and was able to get it scanned through a bunch of free or nearly-free sequencers (FoundMyFitness, Athletigen, Promethease, Geneticgenie).…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view
Re: My doctors will not even discuss anything unapproved @Gage Gage is spot-on. If you need surgery or prescription meds, ask your doctor. For good diet, an exercise plan, good supplements, or anything else for actually increasing healthspan & lifespan,…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- 1
- General Discussion
- Reported - view
Re: New guy here. HRS -- slow aging enough, and you effectively slow it to zero. Naked mole rats have extremely long lifespans because their rate of aging is effectively almost zero.…
- Paul Tozour
- Paul_Tozour
- 2 yrs ago
- General Discussion
- Reported - view

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