Will Glycine Supplementation Reduce Homocysteine?
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Thank you Michael, insightful as usual with your posts :-)
A couple of comments not in order:
- I cycle from time to time with NAC and when I do I use Glycine, see GlyNAC evidence ...
- Be careful in measuring homocysteine after strenuous exercise: there is evidence of induced increase, e.g. see Deminice R, Ribeiro DF, Frajacomo FTT. The effects of acute exercise and exercise training on plasma homocysteine: a meta-analysis. Bearden SE, ed. PLoS ONE. 2016;11(3):e0151653, https://journals.plo...al.pone.0151653
- I am tracking homocysteine since many years and somehow succeed to keep it in check, not as I wished (say ~7) but trending down over 16 years, from ~14 to ~11 now at 67 yo. NR (form of B3), supplementation with other vitamins of the B group and possibly Glycine might have been useful but cannot prove it.
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Thanks albedo . Based on the glycine-->serine conversion, and then the conversion of homocysteine-->cystathionine-->cysteine, NAC may not be necessary, as you'd have 2 of GSH's 3 component amino acids (cysteine and glycine).
The 2 days prior to every blood test are purposefully limited in terms of exercise so that the results aren't impacted by my usual workout.