What alternative clinics or strategies should be taken into account for pancreatic cancer Patients ?

Because cancer is directly associated with aging I would like to ask in this forum, what are some of the alternative clinics and treatment strategies I could look into, regarding pancreatic cancer. There are a lot of studies on PubMed regarding metformin,  rapamycin, fisetin, in cell lines, and in patients. I have a family member that has relapsed from pancreatic cancer, and I'm trying to collect the best actionable information. I would welcome any tips of clinical trials or any other information that you guys could point me to. Thanks 

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  • Sorry to hear that. You can compile a doc like this. (50 pages of articles about "kidney cancer <bla>"). I actually strongly encourage compiling a doc like this, and research the supplements listed in this doc via "pancreatic cancer curcumin" etc Google searches. In a nutshell,

    i) There's observational evidence that Metformin, Statins increase your chances of survival against a variety of cancers.  Those are some of the first things to research and consider. 

    ii) Weekly Rapamycin, I believe, shouldn't hurt. Evorilimus is an FDA approved drug for many cancers including pancreatic cancer.  Weekly rapamycin should supress mTOR and improve anti-cancer, immunity I believe. You can get a prescription from an anti-aging Dr (even online) or try to order overseas (I couldn't). 

    iii) Consult with careoncology.com (telemedicine Dr in USA to get prescriptions for metformin, statin, mebendazole etc). 

    iv) A bunch of supplements (probably curcumin and others) and other drugs like aspirin (anti-metastatic effects) , 20mg melatonin, Vit D, etc. I'd research each of them. 

    v) LDN may be something to consider. The evidence base is weaker but some interesting anecdotal examples. Very safe. ldndirect.com for online (legit) prescription.

    vi) Become a member of Jane McLelland Off Label Drugs (Facebook group), check out things like my cancer story rocks (blog + FB group), Chris beat cancer (book + FB group etc). 

    vii) CBD and full spectrum oil have ardent supporters, and some anectodal evidence. 

    Just sharing what I know. Hope this helps. Please research for your particular condition and/or consult with an MD. 

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      • JPA
      • JPA
      • 4 mths ago
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      Gokhan Thank you for all this information, I will definitely try to compile all the information into a google doc as in the example you have shown. 

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  • Because this is a ton of work, I can see that finding a clinic who's done this work for you would be awesome.

     

    1) careoncology is a starting point, but their treatment will probably be limited to metfomin, statin, antibiotic, de-wormer, anti-histamine, medicinal mushrooms, melatonin. I guess it's a good start. 

     

    2) This is another doc (they do liquid biopsies, plus probably a bunch of other things). 

    > We do have telemedicine consultations. If interested please go to our website medicorcancer.com in the downloads you will find new patient forms they would have to be filled out and returned, directions are given in the package, once sent you may email to see if we had received and we can go from there and make an appointment. A telemedicine consult is $950.00 Cdn.

    Medicor Cancer Centres

    info@medicorcancer.com

    P) 416-227-0037

    I haven't used their services. So I'm not super sure what treatment options they offer. 


    3)  Melanoma Survivor Story: Healing Stage 4 Melanoma in 6 Weeks! (Bailey O'Brien)

    https://www.youtube.com/watch?v=6tRhkYQ9q-g -- very inspiring video if you've exhausted your conventional options. 

    https://www.baileyobrien.com/what-i-did

    * Gerson Therapy Q&A with Dr. Patrick Vickers of Northern Baja Healing Center

    https://www.youtube.com/watch?time_continue=195&v=XCLQN4W3nwc

     

    Feel free to PM me for anything else. Best. 

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      • JPA
      • JPA
      • 4 mths ago
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      Gokhan I live in Portugal, so I'm going to try to find an Intergrative Oncologist in Europe, thank you for these links to Integrative Oncologist clinics

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      • JPA
      • JPA
      • 4 mths ago
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      Gokhan Regarding Mushrooms, I have found these cases, that seem worth looking at:

      https://pubmed.ncbi.nlm.nih.gov/27257527/

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890100/

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890094/

      They are cases that Researcher Paul Stamets has talked about in some interviews, of how turkey tail mushrooms increase NK cells activity. In one of the cases, it was of his mother, who was the only survivor of a Herceptin clinical trial with 50 patients. Herceptin has recently been approved for Pancreatic Cancer so it's something I found would be worth looking at

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  • https://youtu.be/wiGVsUtCZwI

    Stage 4 cancer success story... Fasting with proper nutrition while fasting.

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      • JPA
      • JPA
      • 4 mths ago
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      Andrew P K Yap Thank you 

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  • https://www.cancer.gov/about-cancer/treatment/cam/patient/vitamin-c-pdq

    Studies of IV vitamin C alone

    Two studies found that patients who received IV vitamin C had better quality of life and fewer side effects than those who did not.

    In a study of healthy volunteers and cancer patients, vitamin C was shown to be safe at doses up to 1.5 g/kg in patients who do not have kidney stones, other kidney diseases, or G6PD deficiency. Studies have also shown that vitamin C levels in the blood are higher when given by IV than when taken by mouth, and last for more than 4 hours

    "Cancer and vitamin C"

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  • Apigenin in cancer therapy: anti-cancer effects and mechanisms of actio
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629766/

    Apigenin is a common dietary flavonoid that is abundantly present in many fruits, vegetables and Chinese medicinal herbs and serves multiple physiological functions, such as strong anti-inflammatory, antioxidant, antibacterial and antiviral activities and blood pressure reduction.

    "Apigenin and cancer"

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  • https://newatlas.com/medical/new-chemical-willow-trees-various-cancer-cells/

    Scientists from the UK’s Rothamsted Research and cancer biologists from the University of Kent have now discovered another chemical in willow trees with plenty of potential. Called miyabeacin, the researchers are particularly excited about how it might prove useful in treating cancers resistant to existing drugs.

    "miyabeacin and cancer"

    Like 1
  • https://www.nature.com/articles/s43018-019-0018-6

    The drug *tepoxalin*, for example, which was originally developed for use in people but later approved for treating osteoarthritis in dogs, worked by attacking a target called MDR1 that’s expressed on the surface of cells and protects them from chemotherapy.

    Corsello said cancer patients who develop resistance to chemotherapy often have high levels of this protein.

    *Antabuse*, a drug approved to treat alcohol dependence, showed activity in cancers that lack a portion of chromosome 16, which commonly occurs in some breast cancers.

    Other drugs showing anti-cancer properties included a compound originally developed to treat diabetes called *vanadium, and levonorgestrel*, a hormone used in contraceptives.

    Like 1
  • Medical News Bulletin: Certain oral microbiota linked to pancreatic cancer, study finds.
    https://medicalnewsbulletin.com/oral-microbiota-and-pancreatic-cancer/
    Gum diseases link to changes in oral microbiota

    Like 1
  • https://www.medicalnewstoday.com/articles/322009.php#1

    The drug itraconazole is typically used in the treatment of fungal infections.

    brand new use for this substance — namely, as a treatment that is able to eliminate dormant tumor cells in colorectal cancer.

    Like 1
  • https://youtu.be/vu45hE9yxN0

    Dog de worming meds for cancer

    Like 1
  • Same as above

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/

    Dog meds to treat cancer

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      • JPA
      • JPA
      • 4 mths ago
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      Andrew P K Yap Thank you for the link

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  • The Times of Israel: In possible breakthrough, molecule destroys pancreatic cancer cells in mice https://www.timesofisrael.com/in-possible-breakthrough-molecule-destroys-pancreatic-cancer-cells-in-mice/

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      • JPA
      • JPA
      • 4 mths ago
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      Andrew P K Yap This one is a little frustrating because there doesn't seem to be a way to get access to this drug, but I will try to look into any way this may be possible

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  • Wrong premise. Children get cancer - of the most vicious forms. Where is aging's role in those instances?

    The best thing to do in this specific instance, is to look everywhere else but pubmed.

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  • I wouldn't hold my breath on rapamycin, metformin or anything else mentioned with a relapse of pancreatic cancer.

    Intravenous application of pharmaceutical grade this that or the other vitamins: what? A, C, D...  What doc is going to pass that nonsense onward?

    Hydrogen peroxide and Hallucinogens.  What else is realistic at this stage?

    Nothing. 

    Do it.

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