Is Young Plasma Really a Worthwhile Treatment for Aging?
The RAADFest 2018 Special Report of September 20, 2018 lists administration of blood plasma taken from young donors as one alternative in Step 4 in dealing with aging. Today a news article in the Huffington Post entitled "He Hawks Young Blood As A New Miracle Treatment - All That’s Missing Is Proof" examines the $8,000 Ambrosia Corp. young-plasma treatment and portrays it as questionable medicine by a marginal MD who never finished his residency at a Boston hospital and is barred from medical practice in Massachusetts.
The article points out that in the often-quoted test with young and old mice with joined circulatory systems, the young mice were negativity impacted by the test far more than the old mice were helped. One of the scientists involved in the test questioned whether it made any sense to administer 2 liters of young plasma to an aged human in a couple of days, based on their mouse experiment.
I question whether the Age Reversal Network should be promoting this scheme.
FWIW my small opinion is that I'm skeptical of the young plasma treatment. One, because it's difficult and expensive.
Two, because it seems so obvious. It makes intuitive sense that giving young blood to old would be rejuvenating, but it's too convenient. If you consider the history of invention, it's usually the not obvious that ends up being a solution to a problem. For example consider Metformin. A diabetes drug that we find has longevity effects - huh? This is unexpected, but most discoveries are like this.
Finally it's as you say, not only do we have no evidence, but we have no idea of the mechanism. Sure it seems obvious that 'something' in the blood must be doing good, but it could be like fecal transplants. You know, the idea that healthy people have healthy gut bacteria so all you got to do is put that bacteria in unhealthy people. Sure - except the unhealthy lifestyle of those people continues to promote unhealthy gut bacteria. Could be the same here, that you might get a 'cocktail' temporary boost but little long term effect as your aged body continues to do what it does.
It could work though, sure. If I was older and richer I might try it.
I think JGC is very right to question this intervention at this point. I have read very little on it but was discussing it with a friend MD regarding the impact on Alzheimer disease. I think it is not at all clear the age the young donor should be, how many transfusions are beneficial and of course the side effects you all have mentioned and they are too many of them for me at this stage.
Taking a step back - what is the purpose of blood? Mainly to transport stuff around the body. In itself it serves little purpose AFAIK, unlike say the liver which performs many complex tasks (converts one thing to another, stores and releases another (glucose), filters out other stuff and moves it to the urine). So by comparison, it's clear that if we, for example, replace the damaged liver of an old person with that of a young they will get a beneficial youthful liver again. Same goes for any other organ, but blood? Here today gone tomorrow.
To be fair I think Bill's take on it is that there are <somethings> in young blood that old blood lacks. So the idea is it's kind of a super supplement. Again that sounds good but we need more evidence in this case given the risks and costs (IMHO).
JGC, there is no question in my mind that young plasma is a very effective anti-aging treatment, I have seen it with my own two eyes! I even paid for the treatment for my girlfriend in Thailand.
Also, I would not take any "hit piece" published in HuffPo too seriously (or much else they print, for that matter IMO)!
Apparently, using a blood transfusion to treat heart disease and high blood pressure is pretty common in Thailand, though it's not considered to be "anti-aging." More like "anti-heart disease and high blood pressure," - which of course are effects of aging.
In my GF's case, she was having chest pains and difficulty breathing for several months, at one point even was on oxygen. "Not enough blood going to the heart," the doctor told her, also he diagnosed the high-blood pressure. He told her she would need a blood transfusion and that she should come back with her son (he's 22 years old).
When she returned, the doctor took a half-liter from the son and administered it to my GF. She walked out of that clinic a few hours later and was fine! She has been healthy ever since, even though the doctor said she must return after 6 months for a second dose (she never did). She certainly looked and acted a lot healthier when I saw her 3 months later. She runs around now and exercises regularly without any heart issues at all! It's been about 2 years since the treatment, I think.
The only thing I question about this Ambrosia company is the $8,000 price tag. My GF was charged for this treatment a whopping 5,000 Baht, which is about $150 US. I know that for a fact because I wound up paying the bill!
IMO the effects of young blood seem pretty similar the the cardiovascular benefits reported for +NAD or GDF11. I suspect the young blood has high levels of both, plus probably some other important molecules we don't know about yet.
My GF still looks her age, and still has gray hairs BTW. But she will obviously live a lot longer from the treatment clearing up the cardiovascular problems. So in that way, it's definitely "anti-aging."
Hi everybody. Just joined. Excited about all the research and potential. Very skeptical about young blood transfusion being a big benefit. Blood cells don't live very long then what ever effect would be gone. $8000.00 for that!?
What about transplanting young bone marrow from accident victims? Not a scientist but it would make more sense. Sure someone did that already.
One component of young blood which may be missing with age is GcMAF. This subjects the individual to aging, infirmity and disease. A supplement was available on the market made from source plasma called GOleic until the FDA banned it as an unapproved drug. No matter to the FDA that GOleic actually brought health back to sick people. The Japanese have found another source for GcMAF. It is called colostrum MAF and can be ordered over the internet. Look at these links for more info. Amazing stuff.
JCG - I use a colostrum GcMAF cream. It costs a little over $250 for 30 ml airless pump jar. You just pump out enough to cover the finger tip and spread on the desired spot or a place that will permit reaching the blood stream. This jar can last up to 3 months. It is kept refrigerated. It works because my Nagalase level has been decreasing to avoid prostate cancer which runs in my family. I don't want to give you my supplier because I am afraid that the evil socialist FDA will try to raid them in the states like they did the doctors who were prescribing GOleic for autism. The pharmaceutical industry is deathly afraid of GcMAF because it cures so many diseases, disorders, syndromes and conditions. It even regrows hair. Look at those links for just a sampling of what it does in the body. It is anti-aging.