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Re: Intro to rapamycin
@Van Van, which Glycol are you referring to? is it propylene glycol or glycerol or PEG 200, 400? Transuctol itself is a glycol. If you use these in creams ,…
- Viktor_Andre
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Intro to rapamycin
@Van Topical sirolimus 0.1% for treating cutaneous microcystic lymphatic malformations in children and adults (TOPICAL): protocol for a multicenter phase 2, within-person, randomized, double-blind,…
- Viktor_Andre
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Intro to rapamycin
@Van Van, you haveto solubilize rapa first in solvent!! I recommend Transuctol for dissloving the drug , in 3ml of Transuctol you can dissolve 100mg of Rapa if not more once you get a clear solution…
- Viktor_Andre
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Juvan’s Neel skin gel
I can see a few issues with the cosmetic gel.First of all it very expensive, not to mention that cosmetic are formulated not to penetrate stratum corneum plus GHK Cu is a water soluble molecule…
- Viktor_Andre
- 2 yrs ago
- Questions & Answers
- Reported - view
Re: Intro to rapamycin
@Jay Orman also DMSO is mentioned here a lot for solubilization...the problem with DMSO is that it will irritate the skin for lon term use even in very small concentration...…
- Viktor_Andre
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Intro to rapamycin
@Jay Orman Jay, You can have a look at Vanicream commercially available ...usually used for topical drug delivery/
- Viktor_Andre
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Making sirolimus cream---Tried to grind a 2mg rapamune pill with a grinder and then dissolve in DMSO to put in cream.
@Laur @JGC You could try Transuctol as a solubilizer since DMSO will cause irritation in along run even in very small concentration
- Viktor_Andre
- 2 yrs ago
- Self-Experimentation
- Reported - view

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