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Re: Fisetin to Clear Senescent Cells @JGC I agree. Because clinical studies haven't been done with the 2 together, it would just be self experimentation. The nice thing about these plant compounds is that they are well studied in other…
- Fairy8i8
- Fairy8i8
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Sebastian Fisetin was found to reduce senescent cells in fat tissue as well. There is really only 1 study on Fisetin as a senolytic. They looked at several possible polyphenols,…
- Fairy8i8
- Fairy8i8
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Jay Orman Also, he us was not taking any prescription medications during the time he took vitamin K. He did take the blood thinners for a year after DVT, but is now off them.…
- Fairy8i8
- Fairy8i8
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Jay Orman He wasn't on blood thinners at all before getting deep vein thrombosis. I was saying that blood thinners work by blocking vitamin K. He got deep vein thrombosis- a blood clot.…
- Fairy8i8
- Fairy8i8
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Brian Valerie I don't experience any side effects, and I take the 20mg/kg for 3 days in a row every 2 weeks. I think it's better if you don't experience negative side effects.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Aaron Interesting symptoms. I felt like I had a sunburn the first time I took it and some random pains. I do get tired when I take it. I no longer get any pains while taking it, but some fatigue.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Florin Thanks for clarifying. I'm really glad you commented! I always got so caught up with the initial groups, that I failed to contemplate the significance of the final group.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Florin I am not familiar with those studies. Would you please provide links to them? Also, most people here are following a conservative approach aligned with the Phase 2 trials being conducted by…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Need Help What was your dose and ingestion method? What else do you take?
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells Just wanted people to know. Apparently, people other than just my uncle and I have experienced a decrease in arthritis symptoms with fisetin use. The Navy is sponsoring a study to look at the…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith Are you personally taking any of these senolytics? It would be nice to get a study combing the 3. However, I think cocktails like that are more likely to be studied by one of the many…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Van Thanks for the list. I would be careful of the doxycycline. It has side some side effects. From Podiatry Today: "Researchers have now shown fluoroquinolones triple the risk of tendon rupture…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Fred Cloud If you look at the Figures 2, it will be clear that it IS possible when you are looking at specific time points. After the first round, the number decreased.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith They have done safety studies on fisetin. The standard ones to determine toxicity of a substance. It doesn't seem to be very toxic. It's also been a supplement and taken for over a decade…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Fred Cloud Yes, you read that right. Fisetin does NOT get rid of 100% of senescent cells. It decreases the number. Here is the study. Look at Figure 2B & 2C.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith Thanks! I'll look at the metastudy. I was referring to the study information included with the drug, which referenced the 40% of people saw a reduction (no specific amount of reduction…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith You bring up some interesting points. 1) I am not familiar with CD38 inhibition, but I do take Elysium (a nicotinimide riboside supplement) to increase NAD+ production.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Fred Cloud Many of the experts are starting companies to clear senescence, so they are looking at making drugs that would clear a lot more cells than just fisetin alone.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson Thanks for reminding me! I only take 1 Broccomax capsule a day, which is a low dose (autistic children were given more daily than me), so I won't be in a hurry the increase my dose.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith I agree with you on combining things. Fahey did do a study comparing sulphoraphane with curcumin, but I haven't looked at it yet. High doses of curcumin have some senolytic effects,…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson Glad to hear you can get Broccomax, although if you are ever in France, Prostaphane could be even better.
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith The only problem is that it takes 2 capsule of Avmacol to get at least the same listed amount as Broccomax. I looked a little deeper, and Broccomax used to not have myrosinase,…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith Sorry, did not see this sooner. I found a 2.5 hour interview Dr. Patrick did with with Fahey. https://youtu.be/Q0lBVCpq8jc I haven't looked at it yet,…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @David H I looked up the podcast. The Alpha Brain reference is linked to Onnit's Alpha Brain supplement. I would be cautious of relying on a competitor's testing as a reliable source for potency.…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith I agree. I would be very interested to know who did the testing and under what conditions. I would also be interested to see how it compares to broccoli sprouts,…
- Fairy8i8
- Fairy8i8
- 3 yrs ago
- Self-Experimentation
- Reported - view

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Fairy8i8

Fairy8i8

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Joined: Mon Oct 14 02:57:58 UTC 2019

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