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Re: Exosomes
Thank you Max. Here is what I found on the site: Umbilical Cord Plasma Concentrate ("Exosomes") Safety Study in Elderly Subjects. Goal: The question seeking to be answered by this Phase 0 pilot…
- albedo
- 6 yrs ago
- General Discussion
- Reported - view
Exosomes

In the last Faloon's letter update where he describes the Betterhumans charity where he directed the last generous $1mio donation he writes: "It is via this fast-tracked approach that regenerative…
- albedo
- 6 yrs ago
- 2replies
- 121
- General Discussion
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
Anyone here who tried to compare aging.ai and Levine's Phenotypic Age results?
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: young.ai
Anyone here who tried to compare aging.ai and Levine's Phenotypic Age results?
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: Need more emphasis on diet
@Lee said: Has anyone else here used the PhenoAge spreadsheet by JGC to measure the results of their dietary/lifestyle/supplement choices? I used both the Phenotypic Age and the Aging.ai tools.…
- albedo
- 6 yrs ago
- General Discussion
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels
@JGC said: I note that LifeExtension offers an Interleukin-6 (IL-6) test for $75, an Interleukin-8 (IL-8) test for $199, and a Cytokine Panel test that includes Interleukin-1 beta (IL-1β),…
- albedo
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels
@JGC said: I note that LifeExtension offers an Interleukin-6 (IL-6) test for $75, an Interleukin-8 (IL-8) test for $199, and a Cytokine Panel test that includes Interleukin-1 beta (IL-1β),…
- albedo
- 6 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Another AI/ML tool for biological age?
Looking at the top 5 biomarkers the paper gives very similar results in terms of their relative importance to predicted age to those already published in 2016 by the team at Insilico Medicine which…
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Another AI/ML tool for biological age?

This is quite interesting but it is still in peer-review status waiting for publication: Wood T, Kelly C, Roberts M and Walsh B. An interpretable machine learning model of biological age [version 1;…
- albedo
- 6 yrs ago
- 1reply
- 83
- Assessing Biological Age
Re: DNA methylation test
@DanMcL Interesting, thank you. Wrt repeated tests with Zymo remember to take into account the variability of their measurements at different points in time.…
- albedo
- 6 yrs ago
- 1
- Assessing Biological Age
- Reported - view
Re: New blood tests can reveal your life expectancy
@albedo @albedo said: Just curious when the Levine et al paper on Phenotypic age which Dan refers to in his original post will be published. For the moment it is still at preprint level.…
- albedo
- 6 yrs ago
- 1
- Assessing Biological Age
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
@JGC @DanMcL Thank you for your replies. Food for thought ...
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
@JGC I understand and I am a bit disappointed this is not addressed in the paper, neither it is in the Phenotypic Age paper yet to be published though.…
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: New blood tests can reveal your life expectancy
Just curious when the Levine et al paper on Phenotypic age which Dan refers to in his original post will be published. For the moment it is still at preprint level.
- albedo
- 6 yrs ago
- 1
- Assessing Biological Age
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
@albedo said: JGC Along the lines of the answer you got from Dr. Horvath (thank you), Dr. Levine answered my note on the relative roles played by the clinical biomarkers used for the phenotypic age…
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: Fisetin to Clear Senescent Cells
You might know about already, I did not: clinical trial to follow at Mayo. I might start with Fisetin after the first results appear, will see ... https://clinicaltrials.…
- albedo
- 6 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging?
@Dennis Yes but you seem to imply that a quantity and frequency are defined or there is some supporting evidence. I am not sure but I am referring mostly to AD.…
- albedo
- 6 yrs ago
- General Discussion
- Reported - view
Re: Need more emphasis on diet
Bruce, I tend to agree with you. You likely know this all but just pop into this review (it is from 2016 though) you migh like. Dato S, Bellizzi D, Rose G, Passarino G.…
- albedo
- 6 yrs ago
- 1
- General Discussion
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging?
I think JGC is very right to question this intervention at this point. I have read very little on it but was discussing it with a friend MD regarding the impact on Alzheimer disease.…
- albedo
- 6 yrs ago
- General Discussion
- Reported - view
Re: DNA methylation test
Hi Dan. Do you know how many CpG sites the DNAage probes? The original Horvath's clock uses 353 sites while the "new" one (Levine's 2018) aka DNAm PhenoAge uses 513.The two only partially overlap.
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: Metformin in practice
I must be the only one in this community trying a low dose 250 mg (sometimes 500 mg) when compared to other experimenters. I am trying this since about 3-4 years,…
- albedo
- 6 yrs ago
- 1
- General Discussion
- Reported - view
Re: DNA methylation test
Hi Dan. No rush but just wonder if you got results. Sorry if I overlooked them in case you posted in another thread. BTW, I wish to congratulate for your activity in this Forum and your posts.…
- albedo
- 6 yrs ago
- Assessing Biological Age
- Reported - view
Re: Fisetin to Clear Senescent Cells
@JGC said: ...The table below summarizes the results: .. Thank you for sharing your results and also look forward to the D+Q tests! In my case I have noticed large variations in the aging.…
- albedo
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: "Senolytic Activator" and Extended Fasting …
@DanMcL Just in case, as I understand you have also read Aubrey's book, I posted something I guess relevant for senolytics and biomarkers here, on the Loncecity Forum.
- albedo
- 6 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: "Senolytic Activator" and Extended Fasting …
@DanMcL said: My approach is that the LE activator is cheap and easy so I'll give it a shot. The problem is none of us have any measure for senolytic activity,…
- albedo
- 6 yrs ago
- 1
- Self-Experimentation
- Reported - view

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