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Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud I subscribe to the "inflamm-aging" theory of aging, which states that "inflammation is one of the seven evolutionarily conserved mechanistic pillars of ageing that are shared by…
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud The comparison strikes me as a good experiment to try. Keep in mind that the main value of both TPE and donation is not in decreased target concentration as measured immediately…
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud TGF-beta, like the inflammatory cytokines, is pleiotropic. It's responsible for positive homeostatic functions in healthy people and also drives multiple pathologies,…
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud – TGF-beta has a couple of negative effects as it rises. It's an immune inhibitor that cancer uses to protect itself. It's also pro-fibrotic driving various fibrotic pathologies.…
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Burgundy Summer - Very interesting. I'm looking forward to going down that rabbit hole. It makes sense. I had all the mercury-based fillings removed from my teeth about 10 years back,…
- Lou_Hawthorne
- 4 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Burgundy Summer – My wife never had the vaccine, at least not against Covid (her immunologist told her she was one of the rare individuals for whom it's truly contraindicated).…
- Lou_Hawthorne
- 4 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud - Thanks! Interesting article. I agree with the targets they highlight: TGF-beta, IL-6 and TNF-α.
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Burgundy Summer – Yes she tried several rounds of red light therapy a few years ago. She liked it but it didn't help her autoimmune condition.
- Lou_Hawthorne
- 4 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
PS. 60% dilution effectively removes 1.8L of plasma components. Compared with 660mL to 800 mL of plasma removed in a single plasma donation, Kiprov is removing 2.25x to 2.…
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Not exactly. First, plasma volume in the average person is 3L (see link below). Second, there is a difference between diluting and exchanging.…
- Lou_Hawthorne
- 4 yrs ago
- 2
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Yes that's correct. My wife also had 4 treatments. That was enough to put her into remission from an autoimmune condition she's had for 10 years. Her last treatment was 2.5 months ago.…
- Lou_Hawthorne
- 4 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud – I've sat through 4 TPE treatments and watched them change the bottles each time. Pretty sure it's in the May Conboy publication too; you can look that up yourself.
- Lou_Hawthorne
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Burgundy Summer – My wife is in remission from a 10 year autoimmune disease following 4 sessions of TPE (stable for 2.5 months now). Could she have achieved the same end point by some other means?…
- Lou_Hawthorne
- 4 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud The difference is volume. A plasma donation is 660-800 mL, whereas TPE replaces 3 liters of plasma with saline/albumin. The hypothesis is that there's a threshold effect;…
- Lou_Hawthorne
- 4 yrs ago
- 2
- General Discussion
- Reported - view

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