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Re: Recent Plasma-Replacement Results
@dale koester I went to a plasma-only facility only once (about an hour away and crowded). Decided to just do local blood bank donations even though they limit me to once a month.…
- Peter.2
- 1 yr ago
- Young Plasma Infusions
- Reported - view
NAD+ Concentration conversion

One maker of a NAD+ booster is claiming their trial was a success based on seeing a 17 ng/ml increase in intracellular NAD+. But they did not provide baseline or control NAD+ levels.…
- Peter.2
- updated 1 yr ago
- 54
- 1
- NAD+ Restoration
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Thanks. I will look at the information and data with that in mind.
- Peter.2
- 3 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Thanks for paper. Was aware of this work but haven't looked at details. I do pay attention to inflammation as it may have an upstream effect on many aging pathways.…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@JGC You might want to check back as age limits at some places have changed recently (I used CSL plasma at age 67 - think their limit is not 72). Aside from plasma-only facilities,…
- Peter.2
- 3 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Thanks for your comments, Fred. I've got all the Conboy's papers, read them thoroughly, and listened carefully to their interviews and Irina's presentations.…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
Kiprov has shown no data which supports using his very expensive TPE vs simply donating plasma (for free), either at a blood bank, or a plasma-only center.…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Lou Hawthorne Key point missed by most I think.
- Peter.2
- 3 yrs ago
- General Discussion
- Reported - view
Re: Recent Plasma-Replacement Results
@dale koester Are you still doing plasma donations? Now that some time has passed have there been any noticeable changes? Or changes in blood work? I've done 800 mls donations a week apart and 500…
- Peter.2
- 3 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Which would you pick, young plasma or plasma dilution?
Conboy Plasma Dilution. I started plasma dilution earlier this year as I found a plasma-only donation center (they pay you), and also donate via my local blood bank.…
- Peter.2
- 3 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Only difference between donating plasma, or platelets/plasma, and whole blood is the time it takes somewhat longer. I've had no side effects. Needle placement process is the same.…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud Thanks. I do need o be systematic. I track most of these except for IL-6, oxLDL, and IGF-1. My hsCRP tends to be low already, always <0.5 as does oxLDL and insulin (about 5).…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
@Fred Cloud I'm not sure how to check for blood changes which are atributable solely to plasma loss. I get the standard CBC panel plus hsCRP and plug into Morgan Levines DNAPhenoage.…
- Peter.2
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now
You have to search them out, but there are plasma donation centers here in Florida (as opposed to blood donation centers) where you can make two donations a week of 600 yo 800 mls.…
- Peter.2
- 3 yrs ago
- 2
- General Discussion
- Reported - view
Re: Recent Plasma-Replacement Results
@Fred Cloud @Fred Cloud Separation of components is done by sedimentation or centrifuge. No mention of membrane or any kind of filtration.
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Levon Since my original post I've learned that my blood bank solicits plasma donations where they remove 600 to 800 mls of plasma and replace with saline. This can be done every month.…
- Peter.2
- 4 yrs ago
- 2
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
Plasma Donation Info As noted in prior posts I've restarted blood donations every 2 months, and just gave my 5th donation. I also received feedback from the donor center about plasma donation as…
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Jim N Thanks for suggestion, but the relatively small volume of blood loss suggest NK cell number might go down by about 8% for a short period. These cells have a half-life of about 2 weeks so will…
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Fred Cloud Thanks for pointing this out. To date I've given whole blood, but have questions in to donation center about their platelet and plasma donation process.…
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Levon No. Nothing physical. But didn't expect that right away. Conboy mentions positive effects on liver, muscle, and hippocampal tissues. Her paper also shows a lot of proteomic changes,…
- Peter.2
- 4 yrs ago
- 2
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Jim N That big drop is consistent with the literature. 53 ng/ml is a much better value that 250 ng/ml, much closer to optimum.
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Jim N Thanks for the heads up on this.
- Peter.2
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
@Levon My ferritin levels tend to be low, < 30 ng/ml. Papers on phlebotomy show major reduction in irons stores with just one donation. Low ferritin can be associated with neurological issues in…
- Peter.2
- 4 yrs ago
- 1
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results
On the recent Conboy study (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288913/pdf/aging-12-103418.pdf ) replacing 50% plasma with saline and albumin,…
- Peter.2
- 4 yrs ago
- 2
- Young Plasma Infusions
- Reported - view

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