Dr Green new Rapamycin high dose

Dr Green has moved up from 10mg a week to 20mg every 2 weeks. Technically that is the same dose, he just doubles it up and waits twice as long before redosing.

I am shocked that he isnt getting the mouth sores at that kind of dose. I wonder if the older you are and the slower your cell division is that maybe you can tolerate these higher doses without side effects?

Is anyone else experimenting with extreme doses or what is your limit?

Here is the clip discussing it.

https://youtu.be/JiyJ_X3YBew?t=2197

53 replies

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    • Hello_World
    • 3 yrs ago
    • Reported - view

    I've noticed several mentions of a slight increase in TC. Does anyone know if there is an impact on sdLDL-P? That would be my biggest concern.

    • MAC2
    • 3 yrs ago
    • Reported - view

    You could of course measure sdLDL (best), but TG/HDL is an excellent, readily tested proxy for sdLDL. So if your TG/HDL became dysregulated solely on Rapamycin intake, something perhaps triggering a deeper look.

     

    https://www.jstage.jst.go.jp/article/jat/10/3/10_3_186/_pdf

    https://scienceofhumanpotential.files.wordpress.com/2016/11/tg-hdl-particle-size.pdf

    https://sci-hub.se/https://doi.org/10.1007/s00380-018-1247-9

    • Brad_Jensen
    • 3 yrs ago
    • Reported - view

    c an i get the fresh grtapefruit juice at a supermarket? I mean in a bottle?

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