Rapamycin and hgh
I’m thinking of beginning rapamycin and I’m in very good physical condition and I’m wondering if anyone who is in excellent condition has started the program and noticed any effects? Also I am 70 years old so I’m going to try it but I have been taking HGH for the last 13 years and thought it was very beneficial. Has anyone taken HGH with rapamycin?
I did read an interesting article which implied HGH could be beneficial because it promotes MTOR2 and rapamycin suppresses MTOR1.
However Dr. Green thinks growth hormone is inconsistent is it promotes Tor and aging.
obviously I will experiment with taking rapamycin without growth hormone and then adding it back in probably taking it days4,5,6, after taking rapamycin.
But I would appreciate anyone who has actually experience relaying their observations.
-
I am currently only on DHEA/Testosterone, my FMD dosen't feel strongly about anything else currently. 55 yo male, excellent health/fitness, strict keto/OMAD.
I did a bit of a deep dive on HGH, and from what I've read, it's PRO-AGING.
Here's a fresh September 2020 review article.
Growth hormone and aging
https://sci-hub.se/10.1007/s11154-020-09593-2
I wrote to the author, since the article pretty much cites evidence that HGH is pro-aging, although he referenced the FAHY HGH trial.
He replied:
"I feel VERY STRONGLY that GH accelerates aging"
-
I see Blagosklonny made a tweet mentioning the same.
https://mobile.twitter.com/Blagosklonny/status/1404903538321465354
-
Hi, John -- I recently joined, & noticed your post. I'm 74, have been taking HgH for about 20 years; recently had 2 courses of F + Q, & would like to start Rapamycin. I sent e-mail last week to Dr. Green, but no response. However, I think some MDs closer to me, near Atlanta, GA, will give me Rx
I was skeptical of Green's position re negatives of HgH, but have heard various arguments over the years, even from holistic MDs. My basic position is we know HgH, DHEA, Testosterone, etc, decline dramatically with age, & if all were so dangerous, the hospital would be filled with 20 year olds, rather than those with nil levels of those hormones.
However, HgH could react negatively with Rapa, etc Any updates with your experience? Thanks.
-
Hi Michael, I find it very interesting that you have been using HGH for 20 years, may I ask you to share some details?
What dosage regimen have you utilize for HGH, and has it changed over the years?
Have you maintained your body weight, height?
Have you had any arthritis, joint or back issues, and weight problems?
What is your subjective opinion about how you seem to be doing compared to your 70’s year old friends' & family?
How’s your hair on your head look?
Have you had any of the epigenic tests done?One thing from firsthand experience I found is rapamycin does raise blood sugar substantially and that if you want to reduce it, metformin while it does reduce blood sugar during HGH usage somewhat, metformin did not reduce blood sugar levels when taking rapamycin for me no matter the dosage (though it did with my wife mimicking this mouse study below), now is that bad or good I have no clue, but I would like to find out.