
Kaufmannprotocol
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- Jennifer Klein
- Sam_Rela
- 5 yrs agoSat. July 20, 2019 - 11:46 am
- 125replies
- giovanna salas3 yrs agoWed. January 19, 2022 - 7:08 pm
Anybody following Dr. Sandra Kaufmann's protocol?
I would like to hear about your experience.
Thanks
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- Ira GoodmanIra MD
- Ira_GoodmanIra_MD
- 5 yrs ago
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Reading the book now. Have not started the protocol yet. Tell me your results please
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
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Thank you for your answer, I am female, 57 and have been taking practically all the recommended molecular agents for 10 months now. My results: definitely more energy, far better sleep, better mental sharpness, probably better skin, lost weight eating the same (didn't have any big issues with weight to start with but still lost about 3 kg) and a good overall feeling (maybe only due to the fact I am doing something against aging). The cons: loads of pills to swallow.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
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I'm getting the book soon and will use it to create a program for us. I've got a number of supplements we take already but it's a hodgepodge made up of what we happened to come across reading the research on our own. I'm hoping to use it to trim down what we're doing and cut the cost of the supplements.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
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Dan That would be great, looking forward to getting this new program. In the meantime, where can I find a list of those anti-aging supplements you guys are taking already?
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
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Jennifer Klein I have a post somewhere detailing but I can't seem to find it. Anyhow the core is NAD, ALA/ALC, Phosphatidylcholine, CoQ10 (Ubiqinol), Quercetin and Resveratrol (enhanced by having taken a NAD regime). Those are the core ones, we take a amino acids to fill in since we're vegan (creatine and another), the rest is mainly plant derivatives.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
Dan Thanks Dan, many of the supplements/adjuvants that you mentioned are included in the Kaufmann Protocol. Amino acids -as Leucine- are included too to prevent sarcopenia in the case of taking Metformin. Looking forward to your feedback once you read the book.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
- Reported - view
Jennifer Klein OK! Thanks for the encouragement, I've been meaning to get around to it and just got the Kindle version. Perusing it this is fantastic, I'm a engineer (nee scientist) so appreciate her digging into the details.
For the ALA/ALC look up Bruce Ames who created the Ames test, which is what is used to detect the effect of (e.g. carcinogenic) compounds on it. There's several videos of him showing the research, this one isn't great but anyhow the point is that the combination of ALA and ALC restores mitochondrial energy production to youthful levels in mice, but fixing the CoQ10/etc production mechanism.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
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Dan Thanks Dan for the video, I will look up more videos and do more reading about the ALA/ALC combination.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
- Reported - view
Jennifer Klein Yes specifically the two together address mitochondrial disfunction, ALC by itself only addresses part of that problem. One thing to note is you need to have sufficient biotin in your diet or supplementation, they found some people with low biotin could suffer from skin flushing.
Otherwise I've done a scan of her book. Excellent work, not as expansive as I expected - I had thought she'd cover more supplements, but she certainly has all the big guns in there. On effects I've talked about I do notice a drop in 'pep' when I go off of them. (Pure anecdotal hand waving) - it could be placebo but I don't think so, it appears to be that without the supplements my general pep goes down, presumably from the mitochondria not functioning as well. Example of this was a period were I simply forgot to take my supplements and didn't notice, but I did notice a drop in energy and focus. Resuming fixed it and my energy came back.
In terms of this the ones that make the biggest difference, that I notice, is ALA/ALC, CoQ10 and PtC.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
Dan There are so many anti-aging supplements and adjuvant out there that one is confused and at loss about what to take. So when I came across this protocol that addresses all aspects of aging, I found in it a perfect guide to what to take. I hear that the doctor is expanding the protocol and up to now there are over 30 molecular agents targeting all the different cellular damage caused by time. There will even be more that she is still working on. So for now I will stick to this list and to date, other than noticeable general improvement (specially energy-wise) I have nothing negative to say about it (other than the inconvenience of too many pills to pop. All the same I appreciate your comments about ALC, CoQ10 and PTC that are not included in the Protocol ... so far.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs ago
- Reported - view
Dan Thanks for reading the book! The list in the book is only 15 of the Agents. There are 30 on the website, KaufmannProtocol.com, and I am constantly working to expand the list.
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- Edward Sutherland
- Edward_Sutherland
- 5 yrs ago
- Reported - view
Hello, I have been doing the Kaufmann protocol "panacea" for a few months now and one result has been to rid myself of inflammation in my right shoulder, that I had for years. I corresponded with Dr. Kaufmann already, and she suggested adding EGCg (green tea extract) to the protocol which I have done. I do not know if there will be many noticeable effects in the near future, but just the idea that it will be possible to outlive my expected expiration date is a huge turn on for me! It is hard for me to remember to take all the capsules in a day so I put all the days ration in one little vial that I carry around with me. A challenge is travelling and taking the immortality supplements along. It can be quite an ambitious task explaining to customs agents that all the 200 colored capsules you are carrying are just your one week ration for age reversal!
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
Edward Sutherland I know exactly what you're talking about with so many pills to take and carry around when not home. I also have that good feeling of doing something to prevent the degeneration that comes with age and not just stand still arms folded. My knee pain is still there but with less intensity and I am hopeful it will eventually disappear altogether. I do take all the anti-inflammatory agents on the protocol. Sometimes I worry whether all those pills are bad for the liver and the kidney. I will soon have some blood tests done and I really hope to see some good results.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs ago
- Reported - view
Edward Sutherland I realize that the plethora of capsules is a pain in the butt! I just ordered the most awesome containers for folks that want to be organized and/or travel a lot to make life a little easier for everyone. I'll post a pic when they arrive.
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- Edward Sutherland
- Edward_Sutherland
- 5 yrs ago
- Reported - view
sandra kaufmann Great idea, maybe it would be possible to put on a sticker like "Notice, contains anti-aging food supplements for personal use only" to soothe customs agents !!
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
sandra kaufmann That is a great idea indeed and I hope there will be for international shipping as well.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
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Edward Sutherland You can temporally come off some of the pills when travelling - it's even recommended such as with Carnosine - and only take the basics "Panacea. This doesn't work of course if you travel most of the time and in this case good luck with the customs agents.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs ago
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Edward Sutherland excellent idea!
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- Edward Sutherland
- Edward_Sutherland
- 5 yrs ago
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Jennifer Klein
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- Edward Sutherland
- Edward_Sutherland
- 5 yrs ago
- Reported - view
Jennifer Klein Yes, the possible side effects and the interaction of the different molecules are a source of concern for me also. Since the supplements I am taking are getting stronger and more potent over time I watch what I take and when. I would never take a high potence Curcumin on an empty stomach for example. Not only liver and kidney, but the whole intestinal tract can be influenced. If I get a bad stomach upset then I take nothing that day anymore for a precaution. The problem now is still that the thresholds for efficacy of many age reversal products are not yet known, so different companies recommend starkly differing dosages !
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
Edward Sutherland Indeed, it is a bit of a gambling game we are playing here, still I believe it is better than sitting back and do nothing. Both my parents had bad old age with an array of many degenerative diseases. They did have the healthy Mediterranean diet and were quite active, but it still caught up with them. So just a healthy lifestyle is not enough... Of course there maybe interactions and side effects with all those molecular pills... we should each do our homework and research and maybe also help each other with remarks and feedback.
Curcumin should be taken with meals, its best absorbed with fatty food, also with black pepper I read. Me, the green tea extract on an empty stomach upsets it, yet it should be taken that way, so it is then up to me to decide.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
- Reported - view
Edward Sutherland If there's bad interactions between supplements then you might as well ask why there aren't the same between all the different parts of food. Eat an Indian dish, I make one and count some 20 ingredients, 1/4 of which are spices. It's vegan, so these are all plants with hundreds of different molecules in each. Plus we add other vegetable sides. A handful of supplements is swamped by the variety of molecules we get from a varied diet.
On supplements, FWIW I'm a decent exerciser, but only do 4 miles a week on the track and the rest of the week 1/2 hour on a stationary bike, plus some Pilates. Yet I run with a buddy who has been doing it his whole life and was competitive, plus daily swimming and biking. Interestingly I'm the one carrying the conversation, he can't run and talk but I can, even though he's the super athlete compared to me. What's different is I'm careful about what I eat and do a lot of supplements/NAD/Metformin and so on. Anecdotal, but I've found that yes it does have impact, as long as you are checking all over your other boxes (diet, exercise, sleep, relationships, creative work, etc).
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- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- Reported - view
Jennifer Klein
Hi!
I have also experienced an upset stomach when I took Green tea extracts (EGCG mega extract) on empty stomach. I could reduce the discomfort in a few ways.
- Take the extract after a cup of real green tea.
- Take the extract with quercetin. (I only use the Quercetin Phytosome).
- Do not use extract at all but try to increase absorption from real green tea in a radical way and drink a fair amount of green tea and:
Drink real green tea on empty stomach and together with a small amount of vitamin C and piperine/black pepper and quercetin.
+ Let the tea water reach boiling before you pour it into the teacup.
+ Let the tea leaves spend a long time with the tealeaves.
As far as I have read these are measures to draw more catechins out of the tea leaves and to get a better absorption from real green tea. Otherwise, when it only comes to prepare a good cup of tea, they don't recommend that green tea should be prepared by using boiling water and they usually recommend that the tea leaves only to be a short time with the leaves. But the longer time and the higher the temperature the more of the healthy substances will come into the tea.
Vitamin C, piperine and quercetin seems to increase the absorption of real green tea. And therefore it is easier to get a meaningful amount of EGCG and other catechins from drinking green tea. I would like to mention that some time ago I wanted to try green tea extracts again.
Then I took the extract with quercetin phytosome and also this time It did not upset my stomach. it is also anecdotal but these are my personal experiences and also based on the information I have been able to find.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs ago
- Reported - view
Staffan Olsson Not surprised about the stomach upset - green tea in its native form is known to give people upset stomachs, never mind concentrating it. There's a chemical in there that a significant portion of the population is sensitive to, I forget the name of it. You can get used to it, when I first started drinking green tea decades ago after discovering it in Japan I could get a bit of a stomach upset, but that disappeared eventually. Don't know if that's possible with a pill - my answer would be to just drink it straight.
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- Jennifer Klein
- Sam_Rela
- 5 yrs ago
- Reported - view
Staffan Olsson Thank you for your tip, also thank you Dan. Green tea contain tannin which is a beneficial antioxidant but does irritate the stomach. I had to try many brands until I found one that doesn't upset my stomach. I try to take green tea in both forms, the extract in pills and the brewed leaves and yes I make sure it is strongly brewed even if it gets bitter and upsets the stomach more. It's very true that you get used to it after some time and the discomfort is minimum. Sometimes I eat a piece of fruit first then the tea, and it works, and if you say that vitamin C helps with the absorption then even better.
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- Edward Sutherland
- Edward_Sutherland
- 5 yrs agoMon. August 26, 2019 - 9:46 pm
- Reported - view
Jennifer Klein
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- Staffan Olsson
- Staffan_Olsson
- 5 yrs agoWed. August 28, 2019 - 4:24 pm
- Reported - view
Dan
Thanks Dan. I did not know that there is a specific substance in green tea that can effect stomach in that way. I can have gotten used to it.
I drink plenty of green tea and quite strong. And usually I take some c-vitamins with green tea - first thing in the morning. Lately I add quercetin to reap the potential synergies with Q. Then some time ago I also tried to add double dose of mega green tea extract to the tea. And that combination did not affect my stomach at all. But when I first tried strong green tea extract (EGCG) I felt really nauseated. Maybe I have gotten used to green tea, as you say is possible.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoTue. September 3, 2019 - 1:39 pm
- Reported - view
Edward Sutherland To answer some of these questions, I never or rarely suggest taking the manufactures recommendations in terms of several capsules of anything a day. I think a slower, more constant infusion of the agents allows for an improved risk/ benefit ratio.
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- Michael
- Michael.1
- 4 yrs agoSun. November 8, 2020 - 8:15 pm
- Reported - view
sandra kaufmann Is there benefit/risk to emptying the capsules and mix as a smoothie, with the remaining agents? Thank you
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- sandra kaufmann
- sandra_kaufmann
- 4 yrs agoMon. November 9, 2020 - 2:44 pm
- Reported - view
Michael As long as they are soluble in whatever you are putting them in, it should be fine. Keep in mind, some of these things taste terrible!!
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- Michael
- Michael.1
- 4 yrs agoTue. November 10, 2020 - 4:36 am
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sandra kaufmann
Thanks for emailing me!
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoTue. August 27, 2019 - 1:42 pm
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This is Dr. Kaufmann of the Kaufmann Protocol. I would love to hear feedback about anyones experience so that I can tweak the system to make it even better! I am continuously looking at new agents ( it takes a while per agent) and will be posting up too date info on the website. KaufmannProtocol.com
I regret that folks are struggling with so many pills, but at the moment there are no other options- But I'm in the same boat, and I'm working on a solution!
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- Jennifer Klein
- Sam_Rela
- 5 yrs agoTue. August 27, 2019 - 2:54 pm
- Reported - view
sandra kaufmann
So great to have you in the forum Dr. Sandra.
Talking about the possible interaction of the different molecular agents, are there any supplements/adjuvants in the protocol that should not be taken together as they may cancel each other's benefit?
As for the relative inconvenience of taking so many pills, I still prefer that to the pricy, unaffordable unpractical methods like NAD infusion, Stem cell therapy, or young blood transfusion.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoTue. August 27, 2019 - 3:10 pm
- Reported - view
Jennifer Klein
Things don't exactly cancel each other out, but if you are going to take several anti-oxidants, I would spread them out over the day. The half lives of these are usually in the 4 to 8 hour mark, so that by late afternoon/evening you still have some coverage.
And I agree, the cost of the other treatments is a bit ridiculous at the moment!
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoWed. August 28, 2019 - 1:05 pm
- Reported - view
sandra kaufmann great to see you here, thanks for joining.
On the ALA I'm glad to see it in your protocol, but are you aware of Dr Bruce Ames (nee Ames Test) work on this and ALC? His research is published and there are also videos on YouTube (linked below) where he gives a talk on this. The point being is that he found while ALA addresses some part of mitochondrial aging, if you combine it with ALC (Acetyl-L-Carnetine) you'd address the rest of it. The two were necessary, and in mouse models he was able to get old mice to nearly as well as young with these two together.
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- ChrisR
- ChrisR
- 5 yrs agoSun. September 1, 2019 - 8:53 pm
- Reported - view
sandra kaufmann I started the PANACEA one month ago. I'm 59, I'm a lean endurance runner and free thinker, I feel better in both area. More endurance and I'm sharper. I also can sleep less... but I wonder if it is really a good news? Also I had a Seborrheic Keratosis on my head, doctor told it was not here to dessapear, but it did (Could it be the Astaxanthin?).
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoTue. September 3, 2019 - 1:31 pm
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Excellent questions! Your body is going to naturally titrate the amount of sleep that you require. If your cells are becoming optimized and getting what they require with less sleep, then great! In general however, most older folks get too little sleep stemming from a sirtuin deficiency which then gets reversed on the protocol and they can finally sleep. In terms of the keratosis, it has components of an inflammatory nature, so both the astaxanthin and the curcumin should help.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoWed. September 4, 2019 - 1:15 pm
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sandra kaufmann This is great to hear. I'm having sleep issues at the moment - typical mid life stuff and probably also aging itself. For focusing on sleep specifically what supplements would you recommend?
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoThu. September 5, 2019 - 1:34 pm
- Reported - view
Dan You need to boost your sirtuins with either pterostilbene or resveratrol, and then make sure you are getting enough NAD replacement.
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- Jennifer Klein
- Sam_Rela
- 5 yrs agoFri. September 6, 2019 - 11:56 am
- Reported - view
sandra kaufmann
I have had sleep issues as well, now I sleep like a baby. I do take both Resveratrol and Pterostilbene, then I take NAD and Melatonin every night, all within your recommended dosing. It works like a charm but I hope I am not overdoing it.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoFri. September 6, 2019 - 12:24 pm
- Reported - view
sandra kaufmann Got all that covered thanks, fortunately it's doing much better, was other issues ... Another good one for sleep is 5-HTP, a serotonin precursor, before bed, and a magnesium to help relax the muscles.
By the way, FWIW your suggested melatonin doses give me a 'melatonin hangover'. I tried them long before reading your book, they're common recommendations and most of the supplements come in these sizes, but they're like sledgehammers. They put me down so deep I don't dream and probably don't get any REM. I use the 300 microgram time release from LE which is pretty perfect, and even at that I'll drop it for a few days every other week or so.
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- Jennifer Klein
- Sam_Rela
- 5 yrs agoFri. September 6, 2019 - 1:27 pm
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Dan I see that every person is a world and reacts differently to medicine/supplements/adjuvants. Me Melatonin gives me way to many dreams... sometimes I have a feeling I have been dreaming the whole night. So at times I get worried that I am getting too much of the REM Sleep and too little of the deep sleep.
I take 4 mg each night and for almost a year now.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoFri. September 6, 2019 - 4:07 pm
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Jennifer Klein Exactly - yeah I can't even imagine 4 mg! I've always been a great sleeper so maybe produce a lot of melatonin already.
Reminds me of another one for sleep which is Glycine, an amino acid I believe. Hibernating bears have loads of it in their brains. Take it before you sleep and you'll have great dreams.
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- Staffan Olsson
- Staffan_Olsson
- 5 yrs agoFri. September 6, 2019 - 7:33 pm
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Dan
I like to mention that I get a good night’s sleep from 300-400 mg standard folic acid that is taken before I lay down in bed. I take it alone or with different kinds of magnesium. But no effect from magnesium threonat, which does not not improve my sleep.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoFri. September 6, 2019 - 7:49 pm
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Staffan Olsson magnesium is just a muscle relaxant I believe, similar to taking an epsom salt bath. I don't find it a huge effect but it does seem to help.
Speaking of which since we've veered into talking about sleep, I've found relaxation exercises to work wonders. I use the Muse EEG headset and their meditation programs to relax the body and calm the mind an hour or two before bed. Really does wonders.
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- Jennifer Klein
- Sam_Rela
- 5 yrs agoSat. September 7, 2019 - 5:29 pm
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Dan
Men in general sleep better than women, maybe it's the testosterone. Your endogenous production of Melatonin must still be good. I know I don't have much left . I do prefer Melatonin to all the other sleep aids because I also want to get the anti-aging benefits it has, the dosing of which (in the protocol) starts at 3 mg.
Here is an anecdote for you: I went to my doctor a few years ago to get some help for my sleep problems and she told me that I could take Melatonin up to 30 mg/night that she herself was taking with no problem. She prescribed 10 mg for me to start with (have been taking smaller doses before) and build up to higher doses but my body didn't like it so I stopped. So my happy medium now after trial and error is the 4 mg.
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoSat. September 7, 2019 - 6:39 pm
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Jennifer Klein Good info thanks. My wife's hormones crashed a bit ago in her 50's and she wasn't sleeping. Her doctors told her that Progresterone promotes good sleep. Once she was on that and estrogen it cleared up, and she also uses the 300 mcg that I use.
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- sandra kaufmann
- sandra_kaufmann
- 5 yrs agoMon. September 23, 2019 - 3:11 pm
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Jennifer Klein Awesome!!! It takes about a month for the SIRTUINS and NAD to kick in to improve the circadian rhythms. And no, you are not overdoing it!
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- charles smith
- Anesthesiologist in Texas
- charles_smith
- 5 yrs agoWed. September 4, 2019 - 1:46 pm
- Reported - view
I have been on the panacea since November, but kicked it into high gear in January with the addition of most of the tier two suggested supplements/adjuncts on the Kaufmann app. I have never felt,looked, or performed better. Dr Kaufmann does not link anti-aging with athletic performance, but I am proof positive that her protocol is making a huge difference for my cycling endeavors. If anyone follows "strava" you can see that I have claimed 'KOM" (king of the mountain..fastest times) on many routes since January. I know Dr Kaufmann has developed the NFL playbook (patent pending) for athletes, but look at the additional supplements and most of them are part of the playbook (spoiler alert, sorry Dr K)!!
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- Danmoderator
- skipping my funeral
- dantheman
- 5 yrs agoFri. September 6, 2019 - 12:26 pm
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charles smith I've also noticed athletic differences. Been running/cycling for decades but nothing special, 30min on an exercise bike and a 4 mile run on the weekend. However my VO2max is 50 - equivalent of a college athlete. I'm 53! During a run I can carry a conversation. I can only attribute this to the healthy living and supplementation.
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- charles smith
- Anesthesiologist in Texas
- charles_smith
- 5 yrs agoFri. September 6, 2019 - 3:04 pm
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Dan I feel ya! However, as you mention, and as Dr Kaufmann notes repeatedly in her book, the supplementation and antiaging protocol is not about diet and exercise, but I feel a lifestyle of consistent exercise and moderation in diets, gives you amazing results. I just wish I had read Dr k's book a decade ago!! As with everything in life, I believe consistency is the key ( along with the protocol, of course)
You Go College Man !!
Charles
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- David H
- David_Hanson
- 4 yrs ago
- Reported - view
sandra kaufmann I think you should consider adding spermidine supplement to your list. Spermidine induces autophagy, suppresses tumors, modulates immune system, protects from cardiovascular diseases, protects brain from brain diseases, and improves stem cell function. It has been proven to lengthen the lives of mice, One of the foods that contains spermidine, a polyamine, is natto. Spermidine can be bought as a supplement. I have found two USA supplement vendors that sell it. A review summary that I am current reading is titled "Spermidine in Health and Disease", DOI: 10.1126/science.aan2788.
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- Curtis Smith
- Curtis_Smith
- 4 yrs ago
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David H Can you mention spermidine sources you'd recommend, IE who you buy frrom for your personal experiments? Is there a cost / dose logic possible like there is for fisetine where some source for spermidine maybe cheaper but less concentrated bu take more?? tnx
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- David H
- David_Hanson
- 4 yrs ago
- Reported - view
Curtis Smith I am aware of three sources of spermidine for consumers in the USA. I have tried two of them and have the third in our fridge which we will take when we finish the others.
1. The first one that I found was from LZRLabs: https://lzrlabs.net/order-37061865
LZRLabs is located in South Carolina - if you buy in quantity their spermidine has the lowest cost. Instructions are to take 1 capsule per day.
2. The second one we have tried is: https://spermidinelife.us/
They are located in California but the manufacturing process is in Austria. (All three of them use natural spermidine from wheat germ.). This one is the most expensive of the three. You take 2 capsules per day.
3. The most recent one that we have is: https://www.primeadine.com/
They named their product primeadine, I suspect because the name spermidine (which is the name given to the active ingredient which was originally discovered in human semen but later found to be in all the cells in our bodies) is controversial and even repugnant to some consumers. They don't hide the fact that primeadine is spermidine. As for me, I have heard a few dozen research papers on spermidine and the name doesn't bother me nor my wife. (It seems to bother women more than men is my observation from reading posts online.)
Primeadine is more expensive than LZRLabs' spermidine but less than SpermidineLife's spermidine. You take 3 capsules of Primeadine each day. (The amount of Spermidine in the 2nd and Primeadine I believe is the same.)
We plan to use Primeadine mostly because I trust the founder of the company. I have been on a zoom session with her and have corresponded with her by email quite a few times already. Oxford University scientists are also involved with the company.
Instagram: https://www.instagram.com/primeadine/
Facebook: https://www.facebook.com/primeadine/
Youtube: https://www.youtube.com/watch?v=dluDCZg87OA
The founder has had her own health problems and she is very concerned and knowledgeable about health. I have no financial arrangement with her or anyone else selling spermidine.
I do believe that everyone should be taking spermidine. My wife and I bought a 6 months supply of Primeadine for our adult son who recently suffered a concussion during an automobile accident.
Finally, we take our spermidine with our evening meal. It seems to us that it much improves our sleep quality after we changed to take it in the evening.
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- Curtis Smith
- Curtis_Smith
- 4 yrs ago
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David H and to all,
Thanks for that great getting started post above!!! Tnx
Might folks comment on their efficacy / value of their spermidine sources?
Other forums discuss fisetin sources and varying efficacy as well. One here buys from alibaba / China which may have product variability (or not). Tnx
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- Jennifer Klein
- Sam_Rela
- 4 yrs ago
- Reported - view
sandra kaufmann Rhodiola : A Promising Anti-Aging Chinese Herb... Whether it's true or not... another agent to examine please Dr. Sandy.
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- sandra kaufmann
- sandra_kaufmann
- 4 yrs ago
- Reported - view
Jennifer Klein I love rhodiola- there will be a chapter on it in the next bnook I can currently working on
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- Jennifer Klein
- Sam_Rela
- 4 yrs ago
- Reported - view
sandra kaufmann Can't wait to read your second book.
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- Staffan Olsson
- Staffan_Olsson
- 4 yrs ago
- Reported - view
David H I find that spermidine makes me sleepy and that it improvs my sleep. So I take it with my evening meal.
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- David H
- David_Hanson
- 4 yrs ago
- Reported - view
Staffan Olsson One of our sons and his wife found that spermidine taken in the evening greatly aids their sleep.
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- Dorian Gray
- Dorian_gray
- 4 yrs ago
- Reported - view
David H This is very interesting. Seeing from the Primeadine Facebook page that spermidine is a prime ingredient in soybeans, why not just make them a regular part of the diet as the Japanese do? Certainly a lot less expensive.
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- David H
- David_Hanson
- 4 yrs ago
- Reported - view
Dorian Gray Leslie Kenny the owner of Oxford Health, the company that sells Primeadine, recently mentioned in a podcast that if you eat natto, you don't need Primeadine. Her comment led me to researching the amount of spermidine in natto. I eat 150gm of homemade natto daily and my wife eats 200gm daily. I believe the amount of spermidine in this amount of natto is 20mg or more while the spermidine supplements have 1mg per daily serving. So when our Primeadine supply is gone, we won't buy it again. If my memory is correct, and I don't know the reason, tofu has little or no spermidine. Soybeans themselves have more spermidine themselves than natto by weight. We will stick with natto for two reasons - 1. Unfermented cooked soybeans causes us to have intestinal distress 2. There are multiple nutritional advantageous changes to soybeans when they are fermented and become natto.
The problem with natto for the general public is that most western people don't like the taste and texture of natto. My wife and I are willing to eat any nutritious vegan food so we don't care about the taste. We have been eating it for one and 1/2 years and we both like it. We do think that homemade natto tastes better than store bought previously frozen natto (which is mostly available in the USA).
My wife's family is Chinese and I have convinced one of her sisters to try natto. I explained that it would very difficult to find a food that is better than your health than natto. Japanese children start eating it early, less than one year old per YouTube videos.
You are right, natto is much less expensive. We pay about about $40 for a 20 lb bag of small soybeans (small is best for natto). We buy it direct from a North Dakota soybean farmer who has told us that she doesn't use chemical sprays on the soybeans and the soybeans are not GMO.
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- Dorian Gray
- Dorian_gray
- 4 yrs ago
- Reported - view
David H Great that you and your wife don't mind putting in a bit of effort and thinking to achieve such a positive thing. It's a rare thing today in the age of "packaged" everything. While I don't eat it on a daily basis, I do consume it frequently. My wife is Japanese so we have been eating the healthy aspects of that culture for forty years now. We have Japanese markets close by so it is easy for us a lot of the things that aren't in regular stores. For natto, we usually get this brand: https://www.meguminatto.com Although she has made it herself often as well as Kimchi which we have regularly also.
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- J Man
- J_Man
- 3 yrs ago
- Reported - view
sandra kaufmann On the page from https://kaufmannprotocol.com/a-note-from-sandy you mentioned that your vision improved. I have read about astaxanthin and carnosine, but I'm interested in what you did if you don't mind telling me more. Thanks.
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- sandra kaufmann
- sandra_kaufmann
- 3 yrs ago
- Reported - view
Jay Orman In addition to the astaxanthin and oral carnosine, I use visomitin (SKQ1) eye drops and NAC eye drops daily. I'm sure the other 50 agents are probably helping a bit as well!
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- J Man
- J_Man
- 3 yrs ago
- Reported - view
sandra kaufmann I am now investigating SKQ1. It may be a viable option. My experience with Can-C for about a year is negative for what my opthalmologist calls a baby cataract in one eye. I researched Can-C (N-alpha-acetylcarnosine eye drops) thoroughly with pubmed documents before trying it and afterward. This simple article seems to sum up my thoughts of Can-C at this time : https://www.eyenews.uk.com/education/the-truth-behind-the-headlines/post/the-truth-behind-the-headlines-aprmay-2018 . The SKQ1 route looks interesting.
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- David H
- David_Hanson
- 3 yrs ago
- Reported - view
Jay Orman My wife and I have been using a 4% NAC product from the UK for the last 16 months. I haven't seen an ophthalmologist nor optometrist during that time. But my cataracts were worsening my vision so that I needed a new prescription every six months for the year before I started with the NAC. My vision, as far as I can tell, has not changed during the last 15 months.
That's the link for them - but I have been ordering it on ebay.
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- J Man
- J_Man
- 3 yrs ago
- Reported - view
David H Do you have time to explain your process for making homemade natto?
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- Michael
- Michael.1
- 4 yrs ago
- Reported - view
Just started it. Every pill. Loads of energy! Pretty amazing.
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- sandra kaufmann
- sandra_kaufmann
- 3 yrs ago
- Reported - view
Michael Fantastic!!!!
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- Curtis Smith
- Curtis_Smith
- 4 yrs ago
- Reported - view
For those who have problems with too many pills; I suggest getting a personal blender. I use a Tribest. Theres a bullet blender... Try the tribest pb-250 for $69.
Add a few inches of water, your pills, blend and drink.
I agree no sense dealing with a hundred pills 2x a day. Tribest comes with lids you can pack a lunch time mix in your lunch bag...
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- Michael
- Michael.1
- 4 yrs ago
- Reported - view
Curtis Smith I found the easiest way to get it over with - in three gulps - is to make an avocado banana yogurt smoothie (to which I also add my Collagen). Might shoot absorption to hell but literally, three piles of pills along with three smoothie gulps; done.
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- Curtis Smith
- Curtis_Smith
- 4 yrs ago
- Reported - view
Michael I'm envious!!!! I have a tolerable form of hietal hernia, which prevents easily swallowing even one pill. I have to open or grind into a smoothie every pill. The personal blender is both convenient and effective for my mountain of morning and evening nutricals. The tribest blender is good little work horse. Just $70 per base and holders. I go through one every year or 2. I have at least one on the shelf as backup since I'm dead in the water without one. Take care with your gulps! :) :)
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- Michael
- Michael.1
- 4 yrs ago
- Reported - view
Curtis Smith LOL Thank you, my brother. Last week I DID ask Dr. Kaufmann about removing the contents from those in capsule form to add directly to a smoothie and she was kind enough to email back saying "There is no reason you cannot put the agents in a smoothie, but some of them taste terrible and you might not enjoy it. As well, you can only do the ones that are water soluble." So, I paid my Daughter to empty the contents of every bottle into sixty individual baggies. My morning routine consists of digesting a bag with a smoothie in 3 gulps and hitting the treadmill for two hours.
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- sandra kaufmann
- sandra_kaufmann
- 3 yrs ago
- Reported - view
Michael Excellent use of your children!!! well done!
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- Michael
- Michael.1
- 3 yrs ago
- Reported - view
sandra kaufmann
lol
I still need to get back in touch with you for consulting.
As an aside, I was considering Viome. Any experience with them?
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- giovanna salas
- giovanna_salas
- 3 yrs ago
- Reported - view
Hello
new to the group, i have been following the protocol for about 5 months, i don't know if i am just not sensitive, i tried a couple of weeks not to take anything, not even my magnesium at night and then i started again the next week and i don't feel a difference. I am taking the recommended dosage. but i won't stop anyways, it may take longer for me, who knows.
My question is about taking them with and without food. I take NAC first thing with EGCG and NAD at waking time and go to workout. when i come back i have my first meal with creatine and whey protein and the supplements listed in panacea plus some other ones like saw palmetto for hair growth. BTW I am a woman, almost 53 years old. i look and feel younger, no pains or aches, lift weights and some cardio.
in the book, Dr Kaufmann only lists ALA to take without food, i used to take it before workout, but then i moved it to in between bfast and lunch, but since i still want to put it as far as i can from food, i put it at 7:00pm, my last meal is usually between 3 to 4pm to increase its benefits with the fasting time while i sleep for autophagy, what do you think about that?
lastly, what about fisetin? when it is best to take it?
thanks
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