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Re: I recently started Metformin for IR, but am having a lot of gut issues,even after 2 weeks . Thoughts about other possible supplements?
Not related to gut issues, but metformin seems to cause me a lot of leg cramps. So much so that I discontinued its use (twice daily at 500mg per dose) Any guidance on how to alleviate this effect?…
- Patrick_McHargue
- 5 yrs ago
- General Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells
I was able to get mine from Bonhoa.
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Suppliers for Metformin(Glycomet), Rapamycin(Sirolimus) and Dasatinib(Sprycel)

For Metformin(Glycomet) https://www.alldaychemist.com/glycomet-500mg-sr.html For Rapamycin(Sirolimus) https://www.alldaychemist.com/siromus-1mg.html For Dasatinib(Sprycel) https://www.bonhoahealth.…
- Patrick_McHargue
- 5 yrs ago
- 224
- 1
- Self-Experimentation
Re: Rapamycin Cost
@Don It seems that they only carry books - at least that's all I see under 'All Products' I use 'AllDayChemist.Com' for rapamycin and metformin. Still looking for a supplier of dasatinib (sprycel)…
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Senolytics
@Sam Biller These folks require a prescription but will send you a list of clinics in your area that may be able to assist with that. We'll see 2what happens.
- Patrick_McHargue
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Don How did you pay IAS? Is the 'wire transfer' option the only payment option available?
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Charles Grashow All Day Chemist
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Metformin in practice
This is a new study that casts some aspersions on the use of metformin late in life. There have been some comments about it in other threads that detail the study's limitations - use of nematodes,…
- Patrick_McHargue
- 5 yrs ago
- General Discussion
- Reported - view
Re: Sources of dasatinib
@GEdwards But then there are studies that seem to question to use of metofrmin later in life. (like me) https://www.biorxiv.org/content/10.1101/863357v1
- Patrick_McHargue
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Late life metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy metabolism

Not sure how to take this. Anyone more knowledgeable care to comment? https://www.biorxiv.org/content/10.1101/863357v1
- Patrick_McHargue
- 5 yrs ago
- 3replies
- 165
- Self-Experimentation
Re: Reversing arteriosclerotic disease
@David Hanson Here's hoping that the animal models pan out, and the FDA allows for the treatment to go forward.
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
@Jason Understood. (and me, just joining a gym)
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
@Jason Thank you very much for compiling this. I hope that many can use this to support their case to their own doctors. I'll be sending this to my o0wn today.…
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Reversing arteriosclerotic disease
DHEA supplements are something you might consider. Inexpensive, and there is evidence of efficaciousness. https://www.ncbi.nlm.nih.gov/pubmed/2969922
- Patrick_McHargue
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
@Jason What studies? I have sent studies I though to be helpful, but my doctor still will not write a presdcription for Metofrmin.
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Good Metformin Research Paper to convince doctor
@Anar Isman This is a great resource. Thank you.
- Patrick_McHargue
- 5 yrs ago
- General Discussion
- Reported - view
Re: High quality, affordable rapamycin (and other anti-aging meds)
@CSC I appreciate the transparency that's being shown. I will continue to use the product line.
- Patrick_McHargue
- 5 yrs ago
- Announcements
- Reported - view
Re: Sources for Metformin?
@JGC I'm glad it worked out for you. I've tried a number of sites, and some work while others don't. Usually, it's payment options that are the problem.…
- Patrick_McHargue
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
There's this website. Easy enough to order, reasonably inexpensive, and payment options work.…
- Patrick_McHargue
- 6 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Quercetin recomendations
@Michael Avenoso Yep. eCheck seems to have worked for me.
- Patrick_McHargue
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
@angie4life Angie - I used ALlDayChemist to order metformin. I then used https://www.antiaging-systems.com/ to order dasatinib. The www.antiaging.clinic just could not get their act together to…
- Patrick_McHargue
- 6 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Sources for Metformin?
@Jim Rice Thanks for posting the AllDayChemist link.
- Patrick_McHargue
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: dasatinib (Dasa-Pro)
@William Gilbert Thank you, sir. I have visited the Bonhoa website and placed an order. Payment instructions are to follow (an empty stump in the woods maybe) We'll see what works.
- Patrick_McHargue
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: dasatinib (Dasa-Pro)
@William Gilbert Thanks for sharing bonhoa! I haven't been able to pay antiaging.clinic, and I've tried a number of ways. Also, they don't provide guidance on how to pay them.
- Patrick_McHargue
- 6 yrs ago
- Self-Experimentation
- Reported - view
Re: Quercetin recomendations
For those that figure out how to pay via wire transfer, please post the steps you used! I have tried a number of ways, but the information they provide for a Western Union transfer is insufficient,…
- Patrick_McHargue
- 6 yrs ago
- Self-Experimentation
- Reported - view

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