Will eating mitigate the effects of Rapamycin?

Rapamycin is targeting the AMPK related pathway which mtor antagonizes. Eating activates mtor and rapamycin reduces mtor.

So what gives? All the dosing in humans just mentions x1 a week every other week but no clarification about the effects of other lifestyle factors that mediate mtor

It stands to reason that a person should should fast while rapamycin, right? Is mtor going to stay suppressed while on rapamycin regardless of eating?