Can one meal a day mitigate the effects of higher protein?

Higher protein intake, specifically Leucine and Methionine is associated with reduced longevity in animal studies. However, total length of time mtor is active each day is playing a large role in longevity too. Staying chronically fed prevents AMPK and autophagy activation by keeping mtor active, even if protein is low.


I don't see any research on protein and longevity that is controlling for length of feeding.


It stands to reason that a person could increase their leucine and methionine to optimize muscle protein synthesis from resistance training while only eating in 2hr period per day and not see diminished longevity.


There is a longevity youtuber named Siim Land that informed me of this idea as seen in this video:

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