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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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Menin, D-serine, and Neurological Age Reversal
There is a new report published in PLOS Biology by a Chinese group led by Lige Leng that provides evidence of a correlation between decline in the protein Menin secreted by the hypothalamus and a…
JGC
Retired Professor of Physics
JGC
1 yr ago
3
replies
134
3
Last reply
DrOhw
1 yr ago
Self-Experimentation
Tracking progress of my experiment
Hi everyone, I wanted to try a self experiment to see if diet and exercise had an effect on my biological age. It has been a while and I wanted to check my progress,…
Dave A
Dave_A
3 yrs ago
5
replies
134
Last reply
Michael
3 yrs ago
Self-Experimentation
CYP3A5 gene and Rapamyacin
I did a full genome last year and just received an updated report of my variants and possible drug tolerances. Checking I found the following on Rapamyacin and the CYP3A5 gene "Patients with the CC…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
134
Self-Experimentation
Rapamycin and Blood Pressure Pills
Is anyone here taking Rapamycin along with high blood-pressure pills (Ace Inhibitors and amLODIPine)? I’m curious, as I’ve been doing a lot of research and the combo doesn’t seem all that positive.…
Paula Marie
Paula_Marie
3 yrs ago
3
replies
133
1
Last reply
Paula Marie
3 yrs ago
Self-Experimentation
Recent constellation has had an effect... again
I wish I had more scientific data to bring, but in messy real life we end up trying various things and it muddies the waters. I've got existing benefits from a heap of stuff already,…
Jack Black
Jack_Black
2 yrs ago
1
reply
130
1
Last reply
Jack Black
2 yrs ago
Self-Experimentation
Lisinopril and Self Experimentation.
Has anyone had any problems with metformin whilst on Lisinopril drug ? Possible interactions are mentioned on advice sites. Dasatinib and Lisinopril also get a mention in this regard.…
Seaside
Seaside
4 yrs ago
10
replies
130
Last reply
MSS
4 yrs ago
Self-Experimentation
Here is another Doctor Who prescribes rapamycin in Las Vegas.
I thought I would provide the name of my Doctor who does prescribes rapamycin but his practice is different from Dr. Green in New York. I have found him to be very knowledgeable and extremely…
John Mcgough
John_Mcgough
4 yrs ago
130
1
Self-Experimentation
Dasatinib testing -- Information about ordering testing for dasatinib and rapamycin, and other compounds
Information about ordering testing for purity and content of dasatinib and rapamycin, and other compounds, has been created. That info, and a lot more that's needed for their safe use,…
JohnnyAdams
moderator
Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
JohnnyAdams
4 yrs ago
2
replies
130
1
Last reply
Maximus Peto
4 yrs ago
Self-Experimentation
Yeast-Displayed GDF11 and Oral Delivery
Through the work of Steve Perry, it appears that taking growth differentiation factor 11 (GDF11) provides definite health benefits and some evidence of rejuvenation.…
JGC
Retired Professor of Physics
JGC
1 yr ago
4
replies
127
1
Last reply
Jay Orman
1 yr ago
Self-Experimentation
Self Administered Anesthetic Dental Injections
Anyone have experience with it? Any recommendations on administration and compounds used? Thank you, CHAMPIONS!
Michael
Michael.1
2 yrs ago
3
replies
127
Last reply
Michael
2 yrs ago
Self-Experimentation
Inflammation and time to change
I've often expressed skepticism at folks who take a supplement and are immediately convinced of its efficacy. I've been on a two year journey to reduce inflammation by reducing Omega 6 and…
Paul Beauchemin
Paul_Beauchemin
2 yrs ago
123
1
Self-Experimentation
Virgin Olive Oil Study
Anyone see this? It's from 2019. Recommended dose? A LITRE a WEEK! https://youtu.be/Uklt4zVVtS0?t=2976
Michael
Michael.1
1 yr ago
1
reply
116
Last reply
Allen DeLaney
3 mths ago
Self-Experimentation
Melatonin - some thoughts
I find melatonin quite interesting not just for its sleep effects, but also for its other effects in terms of cellular health. Hence I have done a video about that.
John Hemming
John_Hemming
2 yrs ago
2
replies
114
2
Last reply
John Hemming
2 yrs ago
Self-Experimentation
My anti-aging journey - How long for the collagen?
Family and I will be addressing the 9 hallmarks of aging, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing,…
Luke Duran
Luke_Duran
6 mths ago
4
replies
112
1
Last reply
Luke Duran
6 mths ago
Self-Experimentation
Hyperbaric oxygen therapy
Hi, What is hyperbaric oxygen therapy and how it will helpful for patient? Researcher Shai Efrati share complete information regarding such question. Hope this will help many patients.
Cherith
Cherith
4 yrs ago
1
reply
111
Last reply
Mark Thimineur
4 yrs ago
Self-Experimentation
immediate release Metformin (irM) possible side effect: bladder/ prostate irritation
I started taking metformin about 1.5 months ago [2x500mg/day] and have noticed an increased urge to urinate. my bladder or prostate, possibly both, seems to react in a very bad way.…
Cristian Lapusan
Cristian_Lapusan
updated
5 yrs ago
1
reply
110
Last reply
Shauna
4 yrs ago
Self-Experimentation
Cimetidine
Cimetidine for immune system modulation here LE article COPL Bill doesn't recommend it for daily use, but on occasion (for example in December for some individuals - not sure why that specifically,…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
108
1
Self-Experimentation
Ray Kurzweil is a mental case
Thoughts? Discuss...discuss
Michael
Michael.1
2 yrs ago
105
Self-Experimentation
Can Senolytic drug cure Chronic kidney disease ?
Could you help to advise about senolytic drug and CKD ?
PuRi
PuRi
3 yrs ago
2
replies
103
Last reply
hellscreamer
3 yrs ago
Self-Experimentation
Immunosenescence anyone?
Hi all! Just dropping by to ask if anyone has been diagnosed with immunosenescence. During some tests to check for auto-immune conditions (I suddenly developed extremely mild peripheral neuropathy…
Moonlitnight
Medical Writer working on age reversal for over 20 yrs
Moonlitnight
updated
9 mths ago
5
replies
100
Last reply
Moonlitnight
7 mths ago
Self-Experimentation
My story (your suggestions) Dr Arvind Poswal
Hi. I am new here. Would like to know your thoughts. I begin by detailing my major life health points. I think I am a good candidate for knowing the effects of many of the anti-ageing medicines.…
Arvind Poswal
Arvind_Poswal
2 yrs ago
99
2
Self-Experimentation
Mitochondria and the Epigenome
I have done another video based upon more recent research.
John Hemming
John_Hemming
2 yrs ago
3
replies
98
Last reply
John Hemming
2 yrs ago
Self-Experimentation
cell metabolism article--that says metformin, resveratrol and rapaymcin dampen the response from good nutrients--Would love to hear thoughts
linda
linda
linda_
2 yrs ago
2
replies
98
Last reply
linda
2 yrs ago
Self-Experimentation
Bkcaffee's experiment experience
I just received my dasatinib (70 mg ). Before I start taking it I'm wanting to contact a dr in the area (alabama) for review. In the meantime I'm gathering info to do this right.…
Brandon Caffee
Brandon_Caffee
updated
3 yrs ago
2
replies
97
Last reply
Jimmy
3 yrs ago
Self-Experimentation
Ferulic acid
How to use ferulic acid and where to buy ferulic acid as supplement for oral use? My plan is to try Ferulic acid and EGCG (Green tea). My aim for this experiment is to see if this combo can clear…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
reply
97
Last reply
Staffan Olsson
4 yrs ago
Self-Experimentation
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