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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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Red Blood Cells Decline During Aging, But Can Be Increased Through Diet
https://www.youtube.com/watch?v=3JpyDiNxNeE&feature=youtu.be
michael lustgarten
michael_lustgarten
3 yrs ago
5
replies
155
Last reply
Michael
2 yrs ago
Self-Experimentation
Exercise Mimetics
[Not medical advice or a recommendation. Sharing for information only.] Exercise being something of an anti-aging aid, the idea of exercise mimetics comes up.…
Jack Black
Jack_Black
2 yrs ago
5
replies
157
1
Last reply
Vasiliy
2 yrs ago
Self-Experimentation
Epithalon
Anyone inject Epithalon? 1) Any suggestions on both reformulating 50mg Epithalon and daily dose? 2) Anyone have experience mixing in a facial cream? (ALA Mark's rapamycin cream as found all over…
Michael
Michael.1
3 yrs ago
5
replies
173
Last reply
Michael
3 yrs ago
Self-Experimentation
High dose nicotinic acid with acetyl-carnitine restores hair color?
I found out that high dose nicotinic acid (3+ grams) with high dose acetyl-carnitine (1+ grams) seems to be able to at least partially restore hair color in my father in his 70s,…
Big Guy
Big_Guy
3 yrs ago
5
replies
449
1
Last reply
Ludovic Debels
3 yrs ago
Self-Experimentation
Tracking progress of my experiment
Hi everyone, I wanted to try a self experiment to see if diet and exercise had an effect on my biological age. It has been a while and I wanted to check my progress,…
Dave A
Dave_A
3 yrs ago
5
replies
134
Last reply
Michael
3 yrs ago
Self-Experimentation
Rapamycin
I have done bio identical hormones for 3 1/2 months before I start Rapamycin. Do I take 5 mg once a week for 3 months and then take a month off and start again?
Suzanne
Suzanne
4 yrs ago
5
replies
286
Last reply
Larry
4 yrs ago
Self-Experimentation
Share, Please
I've seen a post or two of someone talking about taking dasatinib + quercitin. I've even seen a detailed dosage schedule and mention of a list of compounding pharmacies that I can't find.…
Rob8311
Rob8311
5 yrs ago
5
replies
274
3
Last reply
Peter5.0
5 yrs ago
Self-Experimentation
Hair regrowth using topical resveratrol and fisetin?
Anyone combine the two into a topical for hair regrowth? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593534/
Michael
Michael.1
10 mths ago
4
replies
199
Last reply
Michael
1 mth ago
Self-Experimentation
First post!.... Introducing myself!
Hi everyone!!! Just call me Lucky So, I'm currently 61 years old and I've been a lifetime exercise and diet enthusiast. In my late teens and early 20's I was a competitive powerlifter and…
Donkey Hotie
Donkey_Hotie
11 mths ago
4
replies
93
2
Last reply
Moonlitnight
4 mths ago
Self-Experimentation
My anti-aging journey - How long for the collagen?
Family and I will be addressing the 9 hallmarks of aging, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing,…
Luke Duran
Luke_Duran
6 mths ago
4
replies
112
1
Last reply
Luke Duran
6 mths ago
Self-Experimentation
Quality of various NMN products
So following the work of Dr David Sinclair ....about 5 months ago I added NMN to my daily supplement regime, taking 500mg on an empty stomach every morning about 7am.…
Donkey Hotie
Donkey_Hotie
10 mths ago
4
replies
68
1
Last reply
Curtis Smith
10 mths ago
Self-Experimentation
Yeast-Displayed GDF11 and Oral Delivery
Through the work of Steve Perry, it appears that taking growth differentiation factor 11 (GDF11) provides definite health benefits and some evidence of rejuvenation.…
JGC
Retired Professor of Physics
JGC
1 yr ago
4
replies
127
1
Last reply
Jay Orman
1 yr ago
Self-Experimentation
Tracking daily steps
Just got on the steps band wagon. Who is tracking their daily steps? What are you averaging? What changes have you noticed? To provide some value, here's a link. https://www.nih.…
Michael
Michael.1
1 yr ago
4
replies
85
Last reply
Michael
1 yr ago
Self-Experimentation
Self-experimentation with variety of supplements and drugs
Greetings, I am 67, male, with type 2 diabetes, heart disease and high blood pressure. Current prescription drugs I take per doctor's order: 2000 mg metformin, 45 mg actos, 80 mg lipitor, 2.…
Kim Mackey
Kim_Mackey
4 yrs ago
4
replies
581
Last reply
JOHN
4 yrs ago
Self-Experimentation
Rapamycin and muscle mass
I often hear rapamycin touted as a way of preserving muscle mass but mTOR is vital for muscle hypertrophy? Can anyone explain this apparent contradiction?…
DAVID W
DAVID_WOODHOUSE
2 yrs ago
4
replies
240
1
Last reply
Michael
2 yrs ago
Self-Experimentation
GDF11 rejuvenation
Has anybody here participated with GDF11 Rejuvenation? Results, experience?
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
4
replies
259
1
Last reply
Dan
moderator
4 yrs ago
Self-Experimentation
Did this paper about D + Q and tumorigenesis concern anyone here?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218402/ Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, which develops in the context of fibrosis and cirrhosis caused by…
Phoenix
phoenix
4 yrs ago
4
replies
153
Last reply
Dan
moderator
4 yrs ago
Self-Experimentation
Menin, D-serine, and Neurological Age Reversal
There is a new report published in PLOS Biology by a Chinese group led by Lige Leng that provides evidence of a correlation between decline in the protein Menin secreted by the hypothalamus and a…
JGC
Retired Professor of Physics
JGC
1 yr ago
3
replies
133
3
Last reply
DrOhw
1 yr ago
Self-Experimentation
Who Else taking Acarbose for longevity?
I started taking Acarbose about 6 months ago after reading the ITP studies that showed a that it and rapamycin are the only two drugs approved for human use that have been shown to significantly…
Brin Chikovski
Brin_Chikovski
updated
3 yrs ago
3
replies
427
Last reply
Alex K. Chen
1 yr ago
Self-Experimentation
Blood Test #4 in 2022: Supplements, Diet
https://www.youtube.com/watch?v=RFGtc6cj1AU
michael lustgarten
michael_lustgarten
1 yr ago
3
replies
62
Last reply
Michael_123
1 yr ago
Self-Experimentation
Deprenyl (Selegiline) as a Longevity Drug?
Prompted by UW Professor Matt Kaeberlein's participation in a panel discussion on ARDD 2022 this morning, I listened to the audio of Kaeberlein's long podcast interview with Tim Ferriss.…
JGC
Retired Professor of Physics
JGC
1 yr ago
3
replies
158
1
Last reply
Staffan Olsson
1 yr ago
Self-Experimentation
Rapamycin cost
Well-studied results show a huge increase in lifespan across the board among mammals with rapamycin (sirolimus CAS 53123-88-9) dosing. Why is not everyone taking it?…
Bart Bear
Bart_Bear
2 yrs ago
3
replies
278
1
Last reply
Laur
1 yr ago
Self-Experimentation
Blood Test #1 in 2022: Supplements, Fitness, Diet
https://www.youtube.com/watch?v=46_Xkj9xQug
michael lustgarten
michael_lustgarten
2 yrs ago
3
replies
94
1
Last reply
shirleyscaringi
1 yr ago
Self-Experimentation
Self Administered Anesthetic Dental Injections
Anyone have experience with it? Any recommendations on administration and compounds used? Thank you, CHAMPIONS!
Michael
Michael.1
2 yrs ago
3
replies
127
Last reply
Michael
2 yrs ago
Self-Experimentation
Biomarkers for those taking Rapamycin....?
Hi all, can I ask what biomarkers those of you who are taking Rapamycin are testing and frequency etc? I've had a quick search but can't seem to find anything.…
Natalie S
Natalie_S
1 yr ago
3
replies
84
Last reply
Brin Chikovski
1 yr ago
Self-Experimentation
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AMPK Activation
GDF11 Restoration
Mesenchymal Stem Cells
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Rapamycin Discussion
Senolytics Discussion
Thymus Regeneration
Young Plasma Infusions
Questions & Answers
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