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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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NAD+ and Cancer
A post on Longecity.org four days ago entitled " NAD+ and Cancer" links to a recent Wistar Institute news release that cautions that boosting NAD+ levels in older animals leads to increased risk of…
Bob S.
Bob_S
5 yrs ago
14
replies
572
Last reply
Jay Orman
2 yrs ago
Self-Experimentation
LDL-C reduction with diet and supplements (no statins)
Hi everyone, I recently came across some interesting videos about the optimal levels of LDL-C at the website, http://plantpositive.com/ . The author of the videos includes screenshots of the…
Maximus Peto
Researcher, website & forum admin
Maximus
5 yrs ago
14
replies
483
2
Last reply
Ajax
4 yrs ago
Self-Experimentation
dasatinib (Dasa-Pro)
'NOTICE: By the end of July IAS will be offering dasatinib (Dasa-Pro) in 12x 40mg double-scored tablets for $99.99 this will be uploaded to www.antiaging.…
CSC
CSC
4 yrs ago
13
replies
521
4
Last reply
Erik A Aronesty
2 yrs ago
Self-Experimentation
Bio-Fisetin, a x25 Boost in Bioavailability?
One of the big problems with senolytic flavenoids like Fisetin and Quercetin is that they have a very low solubility in water and poor survival in the digestive tract,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
13
replies
1058
4
Last reply
UB
2 yrs ago
Self-Experimentation
Fisetin and Sleep
I am trying to find out more about the interplay between Fisetin and sleep. I noted there is another thread that looks more widely at Fisetin in which some sleep problems are mentioned.…
John Hemming
John_Hemming
2 yrs ago
12
replies
486
1
Last reply
Moonlitnight
4 mths ago
Self-Experimentation
Calorie Restriction, Eat Once Every Other Day (EOD Diet)
I'm thinking about doing this. I'm not sure if I will have the will power to do so. The EOD Diet will reduce my calorie intake by more than 50%. My goal is to reduce my epigenetic age.…
Jimmy
Jim_N
updated
2 yrs ago
12
replies
300
Last reply
Michael
2 yrs ago
Self-Experimentation
Paul's Anti-Aging Efforts
Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…
Paul Mason
Paul_Mason
5 yrs ago
12
replies
1359
4
Last reply
Simon Lee
3 yrs ago
Self-Experimentation
Rapamycin and APOE4 gene.
According to Dr. Alan Green, Rapamycin is particularly effective in APOE4 carriers, ameliorating the effects of atherosclerosis and Alzheimer's. Does anyone have any experience with either of these…
Jonathan Horwitz
Jonathan_Horwitz
4 yrs ago
12
replies
315
Last reply
MAC
4 yrs ago
Self-Experimentation
The purity of Lucidias-brand Dasatinib
Last year I obtained a 60-tablet bottle of 50 mg Lucidias-brand Dasatinib from BonHoa Pharmacy in New Deli, India, link https://www.bonhoa.com. It seems to be manufactured by Lucius Pharmaceuticals…
JGC
Retired Professor of Physics
JGC
5 yrs ago
12
replies
470
5
Last reply
Louise B Andrew
4 yrs ago
Self-Experimentation
Biological Age Test #4 in 2020: Getting Better or Getting Worse?
michael lustgarten
michael_lustgarten
3 yrs ago
11
replies
226
Last reply
MAC
3 yrs ago
Self-Experimentation
EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks
Andrew P K Yap
Andrew_P_K_Yap
3 yrs ago
11
replies
260
Last reply
Rhett Barret
3 yrs ago
Self-Experimentation
Reversing arteriosclerotic disease
I think the forum could benefit from the topic “reversing arteriosclerotic disease”. This since arteriosclerosis is one of the main culprits that shorten the life of many human beings.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
11
replies
355
3
Last reply
Staffan Olsson
4 yrs ago
Self-Experimentation
Kidney Function Declines During Aging-Can It Be Reversed?
In the video: Data for changes in kidney function during aging, kidney function values that are associated with an increased risk of death for all causes What's my data for kidney function,…
michael lustgarten
michael_lustgarten
3 yrs ago
10
replies
302
Last reply
Edward Meininger
3 yrs ago
Self-Experimentation
Senolytic Self-experiments and COVID-19
There is evidence that the TOP2 receptor that the COVID-19 virus uses to enter cells is more prevalent in senescent cells. Also, clearing accumulated senescent cells from the immune system probably…
JGC
Retired Professor of Physics
JGC
3 yrs ago
10
replies
262
1
Last reply
Andrew P K Yap
3 yrs ago
Self-Experimentation
Lisinopril and Self Experimentation.
Has anyone had any problems with metformin whilst on Lisinopril drug ? Possible interactions are mentioned on advice sites. Dasatinib and Lisinopril also get a mention in this regard.…
Seaside
Seaside
4 yrs ago
10
replies
130
Last reply
MSS
3 yrs ago
Self-Experimentation
Low-Dose Oral Minoxidil for Hair Regrowth
There is an interesting article in today's New York Times describing an accidental discovery by an Australian MD. He found that Minoxidil (trade name Rogaine) when taken orally at very low dose…
JGC
Retired Professor of Physics
JGC
1 yr ago
9
replies
312
3
Last reply
Alerk Kross
1 yr ago
Self-Experimentation
D.I.Y. patches for supplement delivery
Is anyone else interested in making your own patches for supplement delivery? Patches are not strictly about age-reversal. They can be used for other vitamins & supplements, too.…
Mike Almerjanski
Mike_Almerjanski
updated
4 yrs ago
9
replies
448
3
Last reply
Michael_123
1 yr ago
Self-Experimentation
Berberine and Melatonin - can this reverse aging of cells?
I am using an unusual mix of Melatonin (taken in the middle of the night,early morning really) and Berberine. This video explains the reasons why this has the potential to demethylate the epigenome…
John Hemming
John_Hemming
2 yrs ago
9
replies
647
1
Last reply
John Hemming
2 yrs ago
Self-Experimentation
Do doctors prescribe rapamycin to people in their 20s?
I'm looking to experiment with Rapamycin. Does anyone have experience with getting it in their 20s?
rapalogical
rapalogical
3 yrs ago
9
replies
302
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
mark t
I was wondering how you made your cream the 2mg in 4oz? 4oz of what? Thank you.
curious
curious
3 yrs ago
9
replies
230
Last reply
Andrew
2 yrs ago
Self-Experimentation
Kaufmann Protocol Analysis
Dr. Sandra Kaufman, an MD anesthesiologist with an interest in aging, wrote a 2017 book entitled The Kaufmann Protocol: Why We Age and How to Stop It, in which she describes her approach to…
JGC
Retired Professor of Physics
JGC
4 yrs ago
9
replies
308
2
Last reply
Dan
moderator
4 yrs ago
Self-Experimentation
An alternative criterion for evaluating a senolytic.
I apologize in advance for my bad English! Quantifying the effectiveness of senolytics is a task for which methodologies are still being developed. Throughout the years,…
Spasov
Spasov
2 yrs ago
8
replies
223
2
Last reply
Michael_123
1 yr ago
Self-Experimentation
Gingernone A is a Better-than-D+Q Senolytic
A post in Lifespan.io discusses a recent paper published last month in PLoS One in which the polyphenol Gingernone A, a strong component of Ginger Root Extract,…
JGC
Retired Professor of Physics
JGC
1 yr ago
8
replies
372
3
Last reply
Karl
1 yr ago
Self-Experimentation
Safe Rapamycin and Metformin mimetics
EGCG and Ginseng are safe mimetics to rapamycin and metformin respectively based off one of Insilico Medicine's AI. I only have a bachelor's degree in biomedicine,…
Robert Ridge
Robert_Ridge
2 yrs ago
8
replies
320
Last reply
UB
2 yrs ago
Self-Experimentation
My Rapamycin Experiment: Male / Early 30s / Non-US Based
Hi, So I'm currently at the early stages of experimenting with Rapamycin, and thought, if I'm going to take an experimental drug, I might as well document the process and see if it can benefit the…
rapa_experimenter
rapa_experimenter
2 yrs ago
8
replies
249
2
Last reply
rapa_experimenter
2 yrs ago
Self-Experimentation
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