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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet?
I've been reading the research on how low-dose lithium looks to be helpful in age mitigation as outlined in links below. I want to try it at the level of 5mg to 10mg a day.…
Brin Chikovski
Brin_Chikovski
updated
3 yrs ago
28
replies
429
1
Last reply
aribadabar
3 yrs ago
Self-Experimentation
Replacing Hormones to Optimal Levels
I’ve been experimenting with exogenous testosterone for over 15 years. At almost 73 I have been able to build and keep muscle. I eat a diet high in protein, lower in carbs and healthy fats.…
Sharon Smith
Sharon_Smith
2 yrs ago
27
replies
576
5
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
Sources for Metformin?
Suggestions? The best source is via your GP. I have script for Metformin due to an undiscovered elevated glucose (check yours first thing in the morning,…
Dan
moderator
skipping my funeral
dantheman
updated
4 yrs ago
27
replies
1066
2
Last reply
Mermaid
4 yrs ago
Self-Experimentation
Current longevity protocol: Should I add rapamycin?
This is my first post here, and I’m hoping to get some insights from people with similar protocols. In particular, I’m curious to hear people’s perspective on rapamycin given my current regimen.…
Simon Smith
Simon_Smith
2 yrs ago
26
replies
552
2
Last reply
Peter H. Howe
1 yr ago
Self-Experimentation
Anti-Aging Self-Experiment with Epitalon (AEDG)
There is a body of evidence, coming primarily from the publications of Vladimir Kh. Khavinson and his group at the Institute of Bioregulation and Gerontology (IB&G) in Moscow,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
25
replies
1187
6
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Mechanism for Immortality
OK guys, here goes. This is controversial so I apologize beforehand. All you need is NMN because it repairs DNA damage and it boots energy via the mitochondria.…
Chan
Chan
4 yrs ago
23
replies
920
Last reply
Chan
2 yrs ago
Self-Experimentation
Dasatinib from Bon Hoa
A couple weeks ago, I placed an order for Lucius Dasatinib from Bon Hoa. So far, I've taken 200 mg on two consecutive days. It had zero effect on me...no nausea, no tiredness, nada.…
Kevin A
Valued_Customer
4 yrs ago
23
replies
236
Last reply
RobH
4 yrs ago
Self-Experimentation
Help: Drastic results on DNA biological age test
Hi I’m a long time reader and first time poster. Advice needed please. I just received my results from myDNAGE which shows my biological age as 69 when my chrono age is 47.…
Vega Rejuvinated
Vega_Rejuvinated
2 yrs ago
22
replies
600
1
Last reply
Bruce B
8 mths ago
Self-Experimentation
Any results from D & Q course?
Has anyone noticed any perceivable results from a D & Q treatment?
Jared
Jared77
2 yrs ago
22
replies
432
Last reply
Michael_123
1 yr ago
Self-Experimentation
Apigenin: An Alternative Way of Boosting NAD+
At the recent Ending Age-Related Diseases 2021 online conference, Dr. Eric Verdin of the Buck Institute gave a talk in which he described the mechanism behind the well-known drop in NAD+ with age,…
JGC
Retired Professor of Physics
JGC
2 yrs ago
22
replies
646
5
Last reply
Staffan Olsson
2 yrs ago
Self-Experimentation
Resveratrol -- value, dose, source?
There is controversy over resveratrol, and its advocates. What is the value of resveratrol as part of an age reversal supplement program? One highly visible individual recommends Resveratrol that is:…
JohnnyAdams
moderator
Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
JohnnyAdams
4 yrs ago
22
replies
874
Last reply
Stevan Lieberman
2 yrs ago
Self-Experimentation
Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age
A recent study published in Nature indicates that as mice age, the autophagy mechanism that clears old and damaged red blood cells falters, reducing the effectiveness of their blood circulation.…
JGC
Retired Professor of Physics
JGC
3 yrs ago
22
replies
358
3
Last reply
aribadabar
2 yrs ago
Self-Experimentation
Can any meaningful conclusions of efficacy/harm ever be drawn form individual experience/"self experimentation"?
Hi. This post might irritate, but I mean well. It's prompted by a useful article I read this morning...about the nocebo effect with statin's. https://www.nejm.org/doi/full/10.…
Steve Roedde
Steve_Roedde
3 yrs ago
22
replies
239
Last reply
John Mcgough
3 yrs ago
Self-Experimentation
Dasatinib update
Just finished a 3 day course of D & Q. The Dasatinib was purchased from Taylor Made Compounding. Dosage was 100 mg D &1000 mg Q. Cost for 6 @50 mg capsules, including shipping was USD $33.…
Charles Grashow
Charles_Grashow
3 yrs ago
21
replies
726
1
Last reply
Jared
1 yr ago
Self-Experimentation
Where to buy rapamycin?
Hey everyone, I’m new to the group. Really cool to see everyone’s experience with Rapamycin. I’m looking to get some myself. I’m actually more interested in it for my cat’s heart condition.…
Stefan Pougatchev
Stefan_Pougatchev
2 yrs ago
21
replies
1110
2
Last reply
Karina
1 yr ago
Self-Experimentation
blood work
OKAY BRAINIACS! After putting off doing blood Dr. Green requested for over a month, and going without fasting, what do these results indicate. 1) heavy smoker 2) Whiskey drinker 3) No breakfast.…
Michael
Michael.1
3 yrs ago
21
replies
231
Last reply
Michael
2 yrs ago
Self-Experimentation
Is it me or is Apigenin not so hot in this forum
Treatment of cells with apigenin or quercetin inhibits CD38 and promotes an increase in intracellular NAD+ levels. An increased NAD+ level decreases protein acetylation through sirtuin activation. ..…
Andrew P K Yap
Andrew_P_K_Yap
3 yrs ago
21
replies
681
Last reply
Michael
3 yrs ago
Self-Experimentation
Quercetin recomendations
I have just ordered some Dasatinib using the link in the other thread here. I have started to look to get Quercetin as well and I see many options to order it online.…
Jeff Fuja
Jeff_Fuja
4 yrs ago
20
replies
561
Last reply
Gleb Merkurev
3 yrs ago
Self-Experimentation
Monitoring Senescent Cell Clearance with Cytokine Levels
Many of us have been attempting to clear our senescent cells with large senolytic doses of Fisetin and/or Dasatinib plus Quercetin. There have been many anecdotal reports of "feeling better" or…
JGC
Retired Professor of Physics
JGC
5 yrs ago
20
replies
513
2
Last reply
Dan Nave
4 yrs ago
Self-Experimentation
Phosphatidylcholine IV
Ray Kurzweil is a fan of Phosphatidylcholine, and seems to be alone in this. Bill and others don't make much truck with it AFAIK. Ray has said he does both IV's and oral supplementation.…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
19
replies
498
1
Last reply
garland
3 yrs ago
Self-Experimentation
Possible negative response to oral NAD+
Hello, My wife and I (~50) have started a NAD+ regime in addition to rest of the other life long regime (vegan, exercise, other suppls). We started with 250mg (sourced from Life Extension),…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
18
replies
1125
2
Last reply
Jay Orman
10 mths ago
Self-Experimentation
Canagliflozin - A One Month Report, Its Good
I've been using Canagliflozin for the past month and really like it. It moderates blood glucose levels and makes it really easy to lose weight. I've lost about 10 lbs in 3 weeks,…
Brin Chikovski
Brin_Chikovski
updated
2 yrs ago
18
replies
816
6
Last reply
Alex K. Chen
1 yr ago
Self-Experimentation
Is spontaneous hair colour restoration normal?
So, I am a 44yo male with a speckling of grey hair, and I have been taking a mix of compounds that are often discussed in the forums. I started in about mid-January this year.…
David Ng
David_Ng
updated
2 yrs ago
17
replies
1340
2
Last reply
Allen DeLaney
2 mths ago
Self-Experimentation
My 80 year old father's proposed regimen. What do you think?
Hi, I'd appreciate a few moments of your time. This is for my 80 year old father. He takes no prescription meds but is in rough shape due to his age and years of less than ideal lifestyle (which we…
cjacek
cjacek
1 yr ago
17
replies
264
1
Last reply
Spasov
1 yr ago
Self-Experimentation
HBOT and Rapamycin protocol
Greetings! I just signed up to this forum. I've been looking for something like this so I could bounce ideas off the group. I recently bought a Hyperbaric Chamber and have been using it off and on.…
Bart Balder
Bart_Balder
2 yrs ago
15
replies
312
3
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
1
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